Recent progress in the identification and in vitro culture of skin organoids [0.03%]
皮肤类器官的鉴定和体外培养最新进展
Yanan Huang,Qing Ye,Jiyuan Wang et al.
Yanan Huang et al.
An organoid is a cell-based structure that shows organ-specific properties and shares a similar spatial organization as the corresponding organ. Organoids possess powerful capability to reproduce the key functions of the associated organ st...
Co-culture with adipose mesenchymal stem cells promotes Blastocyst formation and gene expression in embryos from aged mice [0.03%]
老龄小鼠胚胎与脂肪源间充质干细胞共培养对其基因表达和囊胚形成率的影响
Yan-Der Hsuuw,Yu-Ting Su,Wen-Hsiung Chan et al.
Yan-Der Hsuuw et al.
Recent studies have highlighted the positive effects of co-culturing embryos with stem cells on embryo development in various mammalian systems. Stem cells secrete numerous factors, including cytokines, growth factors, and microRNAs, which ...
MSC-derived extracellular vesicles: Precision miRNA delivery for overcoming cancer therapy resistance [0.03%]
基于间充质干细胞的外泌体：用于克服癌症治疗耐药性的精准递送miRNA疗法
Ahsas Goyal,Muhammad Afzal,Kavita Goyal et al.
Ahsas Goyal et al.
Cancer remains a prominent worldwide health concern, presenting existing therapies with frequent difficulties, including major toxicity, limited effectiveness, and treatment resistance emergence. These issues highlight the necessity for nov...
Human corneal organoid has a limbal function that supplies epithelium to the cornea with limbal deficiency [0.03%]
人角膜类器官具有对角膜缘缺损供应该类器官上皮细胞的功能
Kazunari Higa,Mifuyu Ishiwata,Reona Kimoto et al.
Kazunari Higa et al.
Introduction: Patients with limbal dysfunction, which occurs when corneal epithelial stem cells are depleted, require the transplantation of donor corneal epithelial stem cells or donor-independent cell sources. This stud...
Apoptotic vesicles inhibit bone marrow adiposity via wnt/β-catenin signaling [0.03%]
凋亡小体通过Wnt/β-连环蛋白信号抑制骨髓脂肪生成
Yuan Zhu,Yaoshan Liu,Kunkun Yang et al.
Yuan Zhu et al.
Background: There is currently increasing focus on aging-related diseases. Osteoporosis is a common disease the incidence of which increases with age. In older patients with osteoporosis, bone marrow mesenchymal stem cell...
Amendment of the Act on the Safety of Regenerative Medicine: A new voyage of regenerative medicine in Japan and the dawn of a new era for young investigators [0.03%]
日本再生医学安全法的修订案——日本再生医疗的新航程与青年研究者的黎明时刻
Ryo Yokomizo,Satoshi Hosoya,Akihiro Umezawa et al.
Ryo Yokomizo et al.
Aiming to promote the safe and appropriate provision of regenerative medicine (RM) in Japan, the Japanese government implemented the Act on the Safety of Regenerative Medicine (RM Act) on November 25, 2014. A supplemental rule of the RM Act...
Novel breast reconstruction technique using ex vivo mononuclear (RE-01) cells and adipose-derived mesenchymal stem cells [0.03%]
一种新型乳房再造技术使用体外单个核(RE-01)细胞和脂肪源间充质干细胞
Ayana Shikanai,Satomi Furukawa,Sen Jiang et al.
Ayana Shikanai et al.
Introduction: Breast reconstruction using fat grafts presents challenges; for example, fat necrosis owing to inadequate blood flow results in reduced engraftment rates. Supplementation of adipose tissue with adipose-deriv...
Actin mesh in Re-epithelialization during skin regeneration in adult newt (Cynops pyrrhogaster) [0.03%]
成年日本火红链新蹄蟾皮肤再生过程中表皮重建时的肌动蛋白网状结构
Yu Liou,Nobuko Moritoki,Tomoko Shindo et al.
Yu Liou et al.
Introduction: Studies have highlighted the role of actin cables in embryonic scarless wound healing across various species. However, evidence for similar structures in adult animals remains lacking. Adult newts, known for...
Fabrication of gelatine/fucoidan nanogel-coated silver nanoparticles for the treatment of wound healing therapy and nursing care [0.03%]
用于伤口愈合治疗和护理的明胶/褐藻胶纳米凝胶包被银纳米粒子的制备
Jiao Hao,Xiaozhen Liu,Yaomiao Du
Jiao Hao
Microbial infections and tissue damage by dressing removal are common problems in wound healing. In this study, gelatine/fucoidan nanogel coated with silver nanoparticles (Ag@Gel/Fu) by simple polymerization technique to assess the antibact...
In vivo evaluation of biocompatibility and biodegradation of porcine collagen membranes [0.03%]
体内评价猪源胶原膜的生物相容性和降解性
Seon Ae Kim,Eun Jeong Go,Bo Seung Bae et al.
Seon Ae Kim et al.
Introduction: Collagen-based materials differ in absorption time, biodegradation patterns, and inflammatory cell infiltration. This study aimed to evaluate the biocompatibility and biodegradation of native, differently pr...