Ex vivo expansion of corneal endothelial cells enabled by small molecule inhibitors of LATS kinase [0.03%]
LATS激酶的小分子抑制剂使角膜内皮细胞能够在体外扩增
Natsuki Abe-Fukasawa,Ryuhei Hayashi,Mio Morita et al.
Natsuki Abe-Fukasawa et al.
Introduction: Transplantation of expanded corneal endothelial cells (CECs) has been regarded as a promising approach for treating corneal diseases caused by CEC damage or dysfunction. However, an efficient method for expa...
Method standardization of secretome production, collection, and characterization: New insights and challenges [0.03%]
分泌组的产生、收集和表征的方法标准化:新见解与挑战
Nivisti Singh,Yahya E Choonara,Pradeep Kumar
Nivisti Singh
Stem cell transplantation remains at the centre of regenerative therapy. Recent, studies have demonstrated that the therapeutic effect of stem cells originates from paracrine reactions from cellular products (secretome) rather than direct c...
Cisplatin-induced acute kidney injury is alleviated by BMSCs-derived exosome via mmu-miR-874-3p-mediated activation of the wnt/β-catenin signaling pathway [0.03%]
骨髓间充质干细胞衍生的外泌体通过mmu-miR-874-3p介导的Wnt/β-catenin信号通路激活缓解顺铂引起的急性肾损伤
Deyang Kong,Zhuohang Yang,Xiaoting Zhang et al.
Deyang Kong et al.
Background: Acute kidney injury (AKI) results from cisplatin chemotherapeutic agents in 30 %-46 % of patients, but clinically effective preventive and therapeutic approaches are lacking. Bone marrow mesenchymal stem cells...
Corrigendum to "Advances in sciatic nerve regeneration: A review of contemporary techniques" [Regen Ther, Volume 29C, (June 2025), 563-574] [0.03%]
关于“坐骨神经再生进展:当代技术综述”的勘误声明[发表于《再生疗法》第29卷C期(2025年6月),页码563-574]
Sardar Ali,Ming Sun,Muhammad Nadeem Khan et al.
Sardar Ali et al.
[This corrects the article DOI: 10.1016/j.reth.2025.04.016.]. © 2025 The Author(s).
Published Erratum
Regenerative therapy. 2025 Aug 23:30:691. DOI:10.1016/j.reth.2025.08.013 2025
Printable biomaterials for 3D brain regenerative scaffolds: An in vivo biocompatibility assessment [0.03%]
用于三维脑组织再生支架的打印生物材料:体内生物相容性评估
Maylis Combeau,Nina Colitti,Julien Clauzel et al.
Maylis Combeau et al.
Background: Brain regeneration after injury is a challenge being tackled by numerous therapeutic strategies in pre-clinical development. There is growing interest in scaffolds implanted in brain lesions. Developments in 3...
Conditioned plasma promotes full-thickness skin defect healing in a rat model [0.03%]
调控血小板丰富血浆促进大鼠全层皮肤缺损愈合
Majid Zamani,Saeid Kaviani,Mehdi Yousefi et al.
Majid Zamani et al.
Introduction: Blood derivatives may enhance wound healing, but each possesses distinct characteristics and has yielded varying outcomes in patient treatment. This research seeks to examine the efficacy of conditioned plas...
Resolve D1 promotions the repair of cornal epidemiological damage in diabetes by regulating epidemiological response and oxidative stress [0.03%]
D1修复糖尿病角膜病变的流行病学机制研究及对流行病学反应和氧化应激的影响
Jiayang Xu,Yuanyuan Qi,Ying Zhu et al.
Jiayang Xu et al.
Objective: It aimed to thoroughly analyze the promotive outcome of Resolvin D1 (RvD1) on the repair of corneal epithelium (CE) damage in diabetes mellitus (DM) mice and its molecular mechanisms. ...
Extracellular vesicles-delivered circDB promotes ischemic muscle repair through the miR-34a/USP7/Notch1 signaling pathway [0.03%]
胞外囊泡递送的环状RNA DB通过miR-34a/USP7/诺太克1信号通路促进缺血性肌肉修复
Lijuan Jiao,Qingfang Han,Yan Xu et al.
Lijuan Jiao et al.
Introduction: The incidence of lower limb ischemic diseases has been rising steadily in recent years, often leading to severe outcomes such as limb amputation. Given the limited availability of effective treatments, there...
The therapeutic potential of neuroglobin-overexpressing human neural stem cells in a photothrombosis model [0.03%]
神经球蛋白过表达的人神经干细胞在光凝血模型中的治疗潜力
Eun-Jung Yoon,Jiwon Jeong,Jisu An et al.
Eun-Jung Yoon et al.
Background: Neuroglobin (NGB) is an oxygen-binding protein with neuroprotective properties under hypoxic and ischemic conditions. It promotes cell survival, reduces oxidative stress, and activates survival-related signali...
Polydactyly bone marrow-derived mesenchymal stem cell-conditioned medium can prevent cartilage degeneration and alleviate knee pain in a rat model of osteoarthritis [0.03%]
多指骨髓源间充质干细胞条件培养基可预防骨关节炎大鼠模型软骨退变及缓解膝痛
Shunsuke Akai,Tomoya Iseki,Yoshitaka Nakao et al.
Shunsuke Akai et al.
Background: Osteoarthritis (OA) is characterized by progressive degeneration of joint cartilage and has substantially increased worldwide. Recently, Mesenchymal stem cells (MSCs) have been explored as a cell-based therapy...