Modeling epithelial wound closure dynamics with AI: A comparative study across cell types [0.03%]
用AI模拟上皮伤口闭合动力学的跨细胞类型比较研究
Xueyao Cai,Weidong Li,Wenjun Shi et al.
Xueyao Cai et al.
Background: Skin wound healing exhibits complex spatiotemporal heterogeneity that challenges traditional static assessment methods. Current artificial intelligence (AI) approaches often treat segmentation and temporal mod...
No simple way to averaging out: Pooled mesenchymal stromal cells do not reflect average donor characteristics [0.03%]
没有简单的方法可以平均化出来：汇集的间充质基质细胞不能反映供体的平均特征
Dea Kukaj,Sabine Niebert,Christoph Biehl et al.
Dea Kukaj et al.
Background: Mesenchymal stromal cells (MSCs) are promising candidates for numerous regenerative therapies. Still, clinical translation is complicated by the heterogeneity of MSCs and related shortcomings in preclinical re...
NN15-017 promotes human pluripotent stem cell proliferation and generation [0.03%]
NN15-017促进人类多能干细胞增殖和生成
Shizuka Fujigaki-Yamazaki,Ryoko Nakatani,Osamu Hirata et al.
Shizuka Fujigaki-Yamazaki et al.
Introduction: The nutrient requirements for culturing human pluripotent stem cells (hPSCs) have been studied in relation to the development of chemically defined media. Most hPSC media contain FGF2, which is critical for ...
Research trends on platelet-rich plasma in improving ovarian dysfunction: A bibliometric and visualization analysis [0.03%]
富血小板血浆改善卵巢功能障碍的研究热点及趋势：基于文献计量与知识图谱的分析
Fangyu Liu,Jiajia Li,Jin Li et al.
Fangyu Liu et al.
Introduction: Platelet-rich plasma (PRP) has attracted attention due to its potential to restore or enhance ovarian function. However, resources for evaluating the research trends of PRP in improving ovarian dysfunction a...
A comprehensive review of clinical trials and Progress in stem cell therapies for advanced heart failure [0.03%]
心力衰竭干细胞治疗临床试验进展的综合述评
Thi-Thu-Hien Tran,Thuy-Linh Tran,Ha-Tung-Chi Nguyen et al.
Thi-Thu-Hien Tran et al.
Heart failure (HF) is a global epidemic with a rising burden on individuals and healthcare systems. Advanced HF is characterized by severe symptoms at rest and marked limitations in physical activity. Stem cell therapies potentially address...
Anastomotic leakage prevention using dry-preserved fibroblast cell sheets in esophageal reconstruction [0.03%]
干燥保存的成纤维细胞片在食管重建中预防吻合口漏的研究
Hiroshi Kurazumi,Ryunosuke Sakamoto,Koji Ueno et al.
Hiroshi Kurazumi et al.
Background: Anastomotic leakage is a common and serious complication of esophageal reconstruction, and new methods are required for its prevention in clinical settings. We herein developed dry-preserved fibroblast cell sh...
Cholangiocyte-derived exosomal miR-381-3p promotes hepatic stellate cell activation and cholestatic liver fibrosis via targeting Klf6 [0.03%]
胆管细胞来源的外泌体miR-381-3p通过靶向Klf6促进肝星状细胞活化和胆汁淤积性肝纤维化
Yang Gao,Yonglin Chen,Yuanyi Mang et al.
Yang Gao et al.
Introduction: The activation of hepatic stellate cells (HSCs) is a central mechanism driving the progression of chronic cholestatic liver diseases (CCLD). MicroRNAs (miRNAs) have been increasingly recognized for their reg...
Advancing the understanding of alveolar regeneration: Global research trends, thematic evolution, and emerging frontiers [0.03%]
推进肺泡再生医学研究：全球科研趋势、主题演化及前沿方向分析
Si-Cheng Zhou,Ying-Xian Dong,Jie Tian et al.
Si-Cheng Zhou et al.
Background: Alveolar regeneration represents a critical research direction in respiratory disease treatment. Despite the surge in studies following the COVID-19 pandemic, comprehensive bibliometric analysis to systematica...
Optimized personnel flow with minimal contamination: development and validation of an air-barrier cleanroom for cell products processing [0.03%]
一种新型气帘洁净室的构建及验证：最小污染下的人员物料流向优化——用于细胞治疗产品的制备过程
Mitsuru Mizuno,Hideaki Tani,Kaori Nomura et al.
Mitsuru Mizuno et al.
Introduction: Cell processing facilities for regenerative medicine require strict prevention of cross-contamination. However, the typically employed sealed, multi-room layout increases energy demands and capital costs due...
Recombinant production of canine vitronectin for optimizing the culture of canine induced pluripotent stem cells [0.03%]
重组犬维生素K依赖蛋白的生产以优化犬诱导多能干细胞培养条件
Kohei Shishida,Yui Ikuta,Hiroko Sugisaki et al.
Kohei Shishida et al.
Introduction: Canine induced pluripotent stem cells (ciPSCs) have attracted attention as valuable tools in veterinary regenerative medicine and disease modeling. Feeder-free culture of ciPSCs using iMatrix-511 has become ...