Systemic MyoAAV-saRNA delivery activates endogenous utrophin and rescues dystrophic pathology in mdx mice [0.03%]
全身递送肌组织MyoAAV-saRNA激活内源性 Utrophin 并在mdx 小鼠中恢复营养不良的病理状态
Zhikai Xiahou,Tianyuan Wang,Zilian Zhang et al.
Zhikai Xiahou et al.
Background: Therapeutic activation of endogenous utrophin, a homolog of dystrophin, represents a mutation-agnostic therapeutic strategy with considerable potential for treating Duchenne muscular dystrophy (DMD). However, ...
The research landscape and trends of dental pulp stem cell studies (2010-2025): A bibliometric analysis [0.03%]
2010-2025年齿髓干细胞研究的科研版图和趋势:文献计量分析
Yu Zheng,Zhe Tang,Lu Li et al.
Yu Zheng et al.
Background: Dental pulp stem cells (DPSCs) have emerged as a promising therapeutic modality in regenerative medicine, yet systematic bibliometric evaluation of global research landscape has been lacking. ...
Autologous bone marrow mononuclear cell transplantation for osteonecrosis of the femoral head in post-covid-19 syndrome: A case series [0.03%]
新冠后综合征股骨头坏死的自体骨髓单个核细胞移植:病例系列报告
Bruno Adelmo Franco,Saulo Garrido,Thiago Faleiro et al.
Bruno Adelmo Franco et al.
Introduction: The emergence of femoral head osteonecrosis in post-COVID-19 patients, possibly related to corticosteroid use, prompted the search for pathophysiological understanding and minimally invasive treatments, such...
The Platelet-Rich Plasma research ecosystem: From mechanistic insights to precision treatment in knee osteoarthritis [0.03%]
富含血小板的血浆研究生态系统:从膝关节骨关节炎的机制洞察到精准治疗
Isabel Andia,Alain Silvestre,Cristina Del Amo et al.
Isabel Andia et al.
Platelet-rich plasma (PRP) is now one of the most widely used orthobiologics in musculoskeletal medicine, with knee osteoarthritis (KOA) as its main indication. PRP represents a spectrum of autologous preparations with differing cellular an...
Hydrogel microcapsulation technology reduces the DMSO concentration required for stem cell cryopreservation [0.03%]
水凝胶微胶囊技术降低干细胞冻存所需的DMSO浓度
Zhongqin Tang,Ying Wang,Ziling Yang et al.
Zhongqin Tang et al.
Introduction: Stem cell therapy is increasingly advancing towards clinical applications, with cryopreservation playing a critical role in cell transplantation. Previous studies have demonstrated that hydrogel microcapsule...
Regenerative effects of PRP-impregnated collagen-gelatin sponge in a full-thickness skin defect model [0.03%]
富血小板血浆载附的胶原-明胶海绵对全层皮肤缺损模型的修复作用研究
Hajime Matsumine,Hiroshi Fujimaki,Yuuki Hasegawa et al.
Hajime Matsumine et al.
Introduction: Artificial dermis is an essential biomaterial for reconstructing full-thickness skin defects. Pelnac G Plus® is a collagen-gelatin sponge (CGS) that can be impregnated with basic fibroblast growth factor (b...
Blood derivatives as monotherapy and combination therapy: A promising strategy for wound healing [0.03%]
单药和联合用药的血液衍生物:促进伤口愈合的一项有前景的战略
Majid Zamani,Mohammad Masumzadeh,Mohammadreza Mohammadi Hosn et al.
Majid Zamani et al.
Wound healing is a highly orchestrated biological process, and any disruption or delay in its progression can result in the formation of chronic wounds. Such conditions impose a considerable clinical and socioeconomic burden on both patient...
Microbiome-based profiles of airborne bacteria to support microbial risk assessment in cleanroom environments [0.03%]
基于微生物组的清洁室环境空气细菌谱系以支持微生物风险评估
Mitsuru Mizuno,Yusuke Ogata,Yuto Nishihara et al.
Mitsuru Mizuno et al.
Introduction: Maintaining aseptic conditions is essential for cell product processing, as sterilization cannot be applied to living cells. Conventional environmental monitoring relies on particle counts and culture-based ...
Magnesium-based alloys for bone regeneration and beyond: A review of advances and therapeutic prospects [0.03%]
镁基骨科合金的最新研究进展及其生物医学应用前景综述
Lu-Hang Xu,Li-Tian Ye,Jia-Yu Wang et al.
Lu-Hang Xu et al.
Background: Magnesium (Mg)-based alloys have gained significant attention as next-generation biodegradable biomaterials due to their bone-mimetic mechanical properties (elastic modulus: 35-45 GPa), biocompatibility, and a...
Objective evaluation of platelet-rich plasma mesotherapy on facial skin quality: An interim split-face analysis using an advanced imaging system [0.03%]
富血小板血浆微针治疗面部皮肤的客观评价:一种先进的影像系统在面部的中期分裂研究分析结果
Masashi Umeda,Takahiko Tamura,Kohki Okumura et al.
Masashi Umeda et al.
Introduction: Autologous platelet-rich plasma (PRP), which is rich in growth factors, is widely used in aesthetic medicine to improve facial skin quality. However, its efficacy has been largely supported by subjective eva...