Female reproductive health-what the classical haematologist needs to know [0.03%]
女性生殖健康-经典血液科医生需要了解什么
Bethany Samuelson Bannow,Imo Akpan,Maureen K Baldwin
Bethany Samuelson Bannow
Haematologists should be prepared to address several key transitions and timepoints during the female reproductive health lifespan to provide safe and equitable care for all patients with haematological disorders. In this Review, we summari...
Inotuzumab ozogamicin in paediatric very high risk first B-cell acute lymphoblastic leukaemia relapse (ITCC-059): a multicentre, single-arm, phase 2 trial [0.03%]
关于Inotuzumab Ozogamicin治疗高危复发性儿童B细胞急性淋巴细胞白血病的多中心、单组、Ⅱ期研究（ITCC-059）
Nicolò Peccatori,Franco Locatelli,Anneke C J Ammerlaan et al.
Nicolò Peccatori et al.
Background: Children with very high-risk first relapse of B-cell acute lymphoblastic leukaemia have very poor outcomes with conventional chemotherapy. Inotuzumab ozogamicin has shown high antitumoral activity in second or...
Real-world patient-reported symptomatic adverse events and concordance with physician assessments after CAR T-cell therapy in patients with aggressive B-cell lymphomas: a prospective study [0.03%]
靶向B细胞淋巴瘤CAR-T治疗患者的现实世界症状型不良事件及其与医师评估的一致性：一项前瞻性研究
Fabio Efficace,Pier Luigi Zinzani,Francesca Bonifazi et al.
Fabio Efficace et al.
Background: Chimeric antigen receptor (CAR) T cells have shown considerable promise in treating patients with haematological malignancies. We aimed to investigate short-term patient-reported symptomatic adverse events in ...
Epcoritamab monotherapy or epcoritamab with lenalidomide as first-line therapy for patients with diffuse large B-cell lymphoma (EPCORE DLBCL-3): primary analysis of an open-label, multicentre, randomised, phase 2 trial [0.03%]
Epcoritamab单药或联合来那度胺作为一线疗法治疗弥漫性大B细胞淋巴瘤（EPCORE DLBCL-3）：一项开放标签、多中心、随机II期试验的初步分析结果
Umberto Vitolo,Juan Miguel Bergua Burgues,Johannes Duell et al.
Umberto Vitolo et al.
Background: Anthracycline-free regimens are needed for older adults with newly diagnosed diffuse large B-cell lymphoma (DLBCL). We aim to evaluate the efficacy and safety of fixed-duration epcoritamab monotherapy versus e...
The Lancet Haematology
The Lancet Haematology
Fabio Torres-Saavedra,Francisco Javier Díaz de la Pinta,Juan Torre-Castro et al.
Fabio Torres-Saavedra et al.
A novel US-based grading system for disease severity in sickle cell disease: the Sickle Cell Outcome Grading System (SCOGS) [0.03%]
一种基于美国的新型分级系统： sickle细胞疾病严重性疾病的SCOGS分级系统
Tarun Aurora,Renee Hodges,Joseph R Wardell et al.
Tarun Aurora et al.
Sickle cell disease is a haematological disorder marked by recurrent events and progressive organ dysfunction, yet a standardised framework to assess disease severity is lacking. We developed a novel US-based severity grading system through...
Donor cell-derived haematological neoplasms after allogeneic haematopoietic cell transplantation: recommendations from the EBMT Practice Harmonisation and Guidelines Committee [0.03%]
造血细胞移植后供者来源的血液系统肿瘤：EBMT实践统一和指南委员会的推荐意见
Carmelo Gurnari,Chris Armstrong,Giorgia Battipaglia et al.
Carmelo Gurnari et al.
Donor cell-derived haematological neoplasms (DDHN) are rare disorders and currently do not have standardised diagnostic criteria and therapeutic management. International experts in allogeneic transplantation and haematological malignancies...
Prediction of bone marrow fibrosis from complete blood count in myeloproliferative neoplasms (FIBOM-AI): a multicentre machine learning model development and validation study [0.03%]
基于完整血液计数的机器学习模型预测骨髓纤维化（FIBOM-AI）：一种多中心建模和验证研究
Marie Donzel,Syrine Khedimallah,Sabrina Barriere et al.
Marie Donzel et al.
Background: Bone marrow biopsy is essential for myeloproliferative neoplasms diagnosis, particularly for assessing bone marrow fibrosis. However, it is an invasive procedure that can be difficult to perform in some patien...
Diagnosis of primary CNS lymphoma through molecular and immune biomarkers in cerebrospinal fluid (PRICELUS): a multicentre, prospective, cohort study [0.03%]
通过脑脊液中的分子和免疫生物标志物诊断原发性中枢神经系统淋巴瘤（PRICELUS）：一项多中心前瞻性队列研究
Josephus L M van Rooij,Peter H Wessels,Johanna M Niers et al.
Josephus L M van Rooij et al.
Background: Primary CNS lymphoma is typically diagnosed by brain biopsy, a procedure with risks and diagnostic delay. Emerging cerebrospinal fluid (CSF) biomarkers, including the myeloid differentiation primary response 8...