Alterations in neuronal morphology in infralimbic cortex predict resistance to fear extinction following acute stress [0.03%]
急性应激后外侧杏仁核形态变化预测侧副皮层恐惧消退的抵抗性
Kelly M Moench,Mouna Maroun,Alexandra Kavushansky et al.
Kelly M Moench et al.
Dysfunction in corticolimbic circuits that mediate the extinction of learned fear responses is thought to underlie the perseveration of fear in stress-related psychopathologies, including post-traumatic stress disorder. Chronic stress produ...
Maternal restraint stress delays maturation of cation-chloride cotransporters and GABAA receptor subunits in the hippocampus of rat pups at puberty [0.03%]
母体应激延迟青春期大鼠海马Cl−稳态相关关键蛋白的表达成熟
Bovorn Veerawatananan,Pornprom Surakul,Nuanchan Chutabhakdikul
Bovorn Veerawatananan
The GABAergic synapse undergoes structural and functional maturation during early brain development. Maternal stress alters GABAergic synapses in the pup's brain that are associated with the pathophysiology of neuropsychiatric disorders in ...
Paraquat and psychological stressor interactions as pertains to Parkinsonian co-morbidity [0.03%]
百草枯及心理压力因素的交互作用对帕金森病共病的影响
Chris Rudyk,Darcy Litteljohn,Shuaib Syed et al.
Chris Rudyk et al.
A number of epidemiological and experimental studies have implicated the non-selective herbicide, paraquat, in the development of sporadic Parkinson's disease (PD). While preclinical research has focused mainly on elucidating the nigrostria...
BA11 FKBP5 expression levels correlate with dendritic spine density in postmortem PTSD and controls [0.03%]
PTSD患者和正常人的FKBP5表达量与树突棘密度相关性研究
Keith A Young,Peter M Thompson,Dianne A Cruz et al.
Keith A Young et al.
Genetic variants of the immunophilin FKBP5 have been implicated in susceptibility to post-traumatic stress disorder (PTSD) and other stress-related disorders. We examined the relationship between mushroom, stubby, thin and filopodial spine ...
Krista B Highland,Michelle Costanzo,Tanja Jovanovic et al.
Krista B Highland et al.
The development of PTSD after military deployment is influenced by a combination of biopsychosocial risk and resilience factors. In particular, physiological factors may mark risk for symptom progression or resiliency. Research in civilian ...
Dong Fang Zhao,Guillermo Becerril-Martinez,David Graham
Dong Fang Zhao
Response to neuropeptide Y: Biomarker and intervention for surgical recovery [0.03%]
神经肽Y的反应:外科手术恢复的生物标志物和干预手段
Nicole Enman,Esther Sabban,Elisabeth J Van Bockstaele
Nicole Enman
Jennifer E Khoury,Andrea Gonzalez,Robert D Levitan et al.
Jennifer E Khoury et al.
Research on the hypothalamic pituitary adrenal (HPA) axis has involved a proliferation of cortisol indices. We surveyed recently published HPA-related articles and identified 15 such indices. We sought to clarify their biometric properties,...
Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain [0.03%]
mGlu7受体阴性变构调节可减少应激敏感大鼠品系的内脏高敏感性
Rachel D Moloney,Anna V Golubeva,Richard M OConnor et al.
Rachel D Moloney et al.
Glutamate, the main excitatory neurotransmitter in the central nervous system, exerts its effect through ionotropic and metabotropic receptors. Of these, group III mGlu receptors (mGlu 4, 6, 7, 8) are among the least studied due to a lack o...
Stress as a one-armed bandit: Differential effects of stress paradigms on the morphology, neurochemistry and behavior in the rodent amygdala [0.03%]
压力的双刃剑作用:压力范式对鼠杏仁体形态、神经化学及行为的异质性影响
Marlene A Wilson,Claudia A Grillo,Jim R Fadel et al.
Marlene A Wilson et al.
Neuroplasticity may be defined as the ability of the central nervous system (CNS) to respond to changes in the internal and external environment and it is well established that some stimuli have the ability to facilitate or impair neuroplas...