Electroacupuncture attenuates anxiety caused by chronic mild stress through inhibiting NOX2-derived oxidative stress in ventral hippocampus [0.03%]
电针通过抑制海马腹侧NOX2来源的氧化应激来缓解慢性轻度不可预知刺激引起的焦虑行为
Tong Yin,Yinxin Wang,Chuan&#x;an Zhu et al.
Tong Yin et al.
Anxiety disorders are highly prevalent and often triggered or worsened by chronic stress, yet current pharmacological treatments have limitations. Electroacupuncture (EA), a modern adaptation of traditional acupuncture, has shown promise as...
Ventral hippocampal autophagy and mitophagy dynamics shape behavioral responses to chronic mild stress in adult male rats [0.03%]
成年雄性大鼠慢性轻度应激的行为反应受背侧海马体自噬和线粒体自噬动态的影响
Paola Brivio,Maria Teresa Gallo,Elena Volpari et al.
Paola Brivio et al.
Major depressive disorder (MDD) is a highly prevalent psychiatric condition characterized by a range of symptoms that often lead to reduced quality of life. Although chronic stress is a major risk factor for the development of MDD, only a s...
Intergenerational influences of paternal combat-related trauma on offspring behavioral and brain function [0.03%]
父亲战斗相关创伤对后代行为和大脑功能的跨代影响
Glenn R Yamakawa,James Freeman,Sydney Harris et al.
Glenn R Yamakawa et al.
Post-traumatic stress (PTS) is a debilitating mental health condition that is highly prevalent in Veteran populations owing to their increased exposure to combat-related trauma. PTS is associated with numerous comorbid conditions including ...
Juan Pablo Lopez
Juan Pablo Lopez
Stress is often described as a fleeting feeling, a momentary surge of tension or anxiety, but in my work as a neurobiologist, I have come to understand it as something far more enduring and complex. It is not merely a reaction to external p...
Increased salivary oxytocin correlates with lower self-reported interoceptive accuracy in functional neurological disorders [0.03%]
唾液催产素升高与功能性神经障碍患者的主观内感受准确性降低有关
Natascha Stoffel,Laure von der Weid,Josef Gross et al.
Natascha Stoffel et al.
Introduction: Functional Neurological Disorder (FND) is shaped by psychosocial stress, early adversity, and neuroendocrine dysregulation. Oxytocin (OXT), a hormone central to stress regulation and interoception, remains l...
Metabolic state shapes cortisol reactivity to acute stress: A systematic review and meta-analysis of metabolic and hormonal modulators [0.03%]
代谢状态影响急性压力下的皮质醇反应：代谢和激素调节因子的系统评价和荟萃分析
Madeleine Kördel,Maria Meier,Anne Kühnel et al.
Madeleine Kördel et al.
Individual variability in cortisol stress responses is shaped by multiple physiological factors. Yet the interaction with metabolic and hormonal states remains poorly understood. Therefore, we conducted a systematic review and meta-analysis...
Potential vulnerability and resilience to accelerated brain aging in women exposed to stressful life events: insights from the brain age prediction model [0.03%]
压力生活事件暴露的女性加速脑衰老的潜在脆弱性和韧性：来自大脑年龄预测模型的启示
Hyeonseok Jeong,Yoonji Joo,Youngeun Shim et al.
Hyeonseok Jeong et al.
Brain age prediction models consistently reveal accelerated brain aging in psychiatric disorders, yet associations with stress, independent of formal psychiatric diagnoses, remain uncertain. This study investigated the relationships of emot...
Cardiometabolic and anxiogenic consequences of chronic social defeat stress in male mice [0.03%]
慢性社会挫败应激对小鼠的心血管代谢及焦虑样行为的影响
Karen A Scott,Sophia A Eikenberry,Khalid Elsaafien et al.
Karen A Scott et al.
Social adversity, such as that which occurs during subjugation to a lower social status, has profound psychological and cardiometabolic consequences that are conserved across species. Clinically, such adversity often arises from being of a ...
Interactive effects of early life adversity and adolescent basolateral amygdala activity on corticolimbic connectivity and behavior [0.03%]
早期生活坎坷与青少年基底外侧杏仁核活动对皮质边缘连接和行为的交互影响
Caitlyn R Cody,Emilce Artur de la Villarmois,Anabel M M Miguelez Fernández et al.
Caitlyn R Cody et al.
Corticolimbic development is shaped by the environment and relies on coordinated neuronal activity. Prior work revealed that early life adversity (ELA) leads to hyperinnervation of basolateral amygdala (BLA) projections to the prefrontal co...
Exposure to early-life stress uncovers shared biological signatures underlying vulnerability in the habenula and insular cortex of male and female adult rats [0.03%]
早期压力暴露揭示了侧缰核和-insular-皮层中潜在脆弱性的共享生物学特征
Valentina Zonca,Moira Marizzoni,Samantha Saleri et al.
Valentina Zonca et al.
Early-life stress (ELS) is a well-known risk factor for the development of several mental disorders later in life. The effect of ELS can be twofold: resilient individuals adapt by perceiving stress as minimal, while vulnerable ones struggle...