The molecular characteristics of colorectal cancer: Impact of Ibuprofen and hyperthermia [0.03%]
结肠直肠癌的分子特征：Indobufen和高温的影响
Farzaneh Zarghampoor,Behnaz Valibeigi,Abbas Behzad-Behbahani
Farzaneh Zarghampoor
Despite various treatment options available for colorectal cancer, the survival rates for patients remain low. This study investigated the effects of hyperthermia and Ibuprofen on human colorectal adenocarcinoma cells (HT-29) viability, pro...
Design and construction of a chimeric peptide, MeICT/IMe-AGAP, from two anti-cancer toxins of Iranian Mesobuthus eupeus scorpion [0.03%]
来自伊朗Eupeasus无棱齿蛇尾蝎的两种抗癌毒素设计构建嵌合多肽MeICT/IMe-AGAP
Razieh Seifi,Hoda Ayat,Ali Mohammad Ahadi
Razieh Seifi
Scorpion venom contains various toxin peptides with pharmacological and biological properties. Scorpion toxins specifically interact with membrane ion channels which play key roles in progression of cancer. Therefore, scorpion toxins have r...
Toxicity and autophagy effects of fluorinated cycloplatinated(II) complex bearing dppm ligand on cancer cells in in-vitro culture and in-silico prediction [0.03%]
含dppm配体氟化二氯铂(II)配合物的毒性及自噬诱导效应的体外和计算机预测研究
Zahra Kamalzade,Elham Hoveizi,Masood Fereidoonnezhad
Zahra Kamalzade
Toxicity and autophagy effects of a new complex of platinum II (CPC) were evaluated on HeLa cells cultured on a PCL/gelatin electrospinning scaffold. HeLa cells were treated with CPC on the first, third, and fifth days and the concentration...
The genetic polymorphisms at the promoter region of HLA-DQB1 gene, creating responsive elements for NF1/CTF and converting the TFII-D binding site to GR-alpha [0.03%]
HLA-DQB1基因启动子区域的遗传多态性，产生NF1/CTF反应元件并把TFII-D结合位点转换成GR-α
Khyber Saify
Khyber Saify
Human leukocyte antigen-DQB1 (HLA-DQB1, OMIM: 604305) is the human major histocompatibility complex (MHC) system. HLA genes are classified into three classes (I, II, and III). The HLA-DQB1 belongs to class II, is mainly involved in the acti...
Investigation and confirmation of differentially expressed miRNAs, as well as target gene prediction in papillary thyroid cancer, with a special emphasis on the autophagy signaling pathway [0.03%]
分化表达的miRNA及其靶基因预测在乳头状甲状腺癌中的研究，着重于自噬信号通路方面的工作
Mojtaba Zehtabi,Zahra Akbarpour,Sepehr Valizadeh et al.
Mojtaba Zehtabi et al.
Papillary thyroid carcinoma (PTC) is the most common endocrine cancer. However, the role of biomechanics in the development and progression of PTC is obscure. The microarray dataset GSE104005 was examined to identify important microRNAs (mi...
Stress adaptation signature into the functional units of spike, envelope, membrane protein and ssRNA of SARS-CoV-2 [0.03%]
SARS-CoV-2刺突、包膜、膜蛋白和ssRNA功能单元的应力适应特征签名
Aniket Sarkar,Anindya Sundar Panja
Aniket Sarkar
Pandemic coronavirus causes respiratory, enteric and sometimes neurological diseases. Proteome data of individual coronavirus strains were already reported. Here we investigated of SARS-CoV-2 ssRNA and protein of spike, envelope and membran...
Mahintaj Dara,Azam Habibi,Negar Azarpira et al.
Mahintaj Dara et al.
Human tears can be used as a noninvasive source of genetic materials and biomarkers in the prognosis and diagnosis of ocular and non-ocular diseases. The present protocol is a novel direct RNA extraction method from tears. This study aims t...
Polymorphisms in CFI and ARMS genes and exudative age-related macular degeneration: Correspondence [0.03%]
CFI和ARMS基因多态性与渗出性年龄相关性黄斑变性：一封信件
Rujittika Mungmunpuntipantip,Viroj Wiwanitkit
Rujittika Mungmunpuntipantip
Phylogenetic analysis and prevalence of Delta hepatitis among HBsAg carriers in Afghanistan [0.03%]
阿富汗乙型肝炎病毒Delta型感染的血清学及基因进化分析
Abbas Ali Husseini,Mehran Rostamzadeh
Abbas Ali Husseini
The molecular profile of hepatitis Delta in Afghanistan remains unclear yet, therefore this study addresses the genotype of HDV among HBsAg carriers in Afghanistan. In total 234 HBsAg-positive sera were examined by chemiluminescent micro-pa...
Genomic analysis of Enterococcus durans NT21, a putative bacteriocin-producing isolate [0.03%]
芽孢杆菌属耐受不了NT21的基因组分析，一种假定的细菌素产生分离株
Nashwa Tarek,Ahmed O El-Gendy,Ahmed S Khairalla et al.
Nashwa Tarek et al.
Enterococcus species are a long-standing and non-pathogenic commensal bacterium, representing an important part of the normal. Enterococcus durans is a rarely isolated species from animals and humans, and it was a tiny constituent of human ...