The importance of examining the Hardy-Weinberg Equilibrium in genetic association studies [0.03%]
在基因关联研究中检验Hardy-Weinberg平衡的重要性
Mostafa Saadat
Mostafa Saadat
Arginine to glutamine mutation in the substrate binding region impaired the isopentenyl activity of Mycobacterium tuberculosis MiaA [0.03%]
底物结合区的精氨酸到谷氨酰胺突变破坏了结核分枝杆菌MiaA的异戊烯基活性
Smitha Soman,Siya Ram
Smitha Soman
tRNAs act as adaptors during protein synthesis and are chemically modified post-transcriptionally for their structural stability as well as accuracy of the translation. Hypomodifications of tRNAs are known to cause various human diseases, i...
MicroRNAs targeting CDKN2A gene as a potential prognostic marker in head and neck squamous cell carcinoma [0.03%]
针对CDKN2A基因的microRNAs作为头颈鳞状细胞癌的潜在预后标记物
Sivakumar Gopalakrishnan,Anitha Pandi,Paramasivam Arumugam et al.
Sivakumar Gopalakrishnan et al.
Epigenetic factors are known to markedly influence the functions of a gene by modification of transcripts, via methylation or acetylation and degradation of mRNA transcripts. The CDKN2A encodes cyclin-dependent kinase inhibitor 2A, a tumour...
Allele and genotype frequencies of β-lactoglobulin gene using PCR-RFLP in Algerian local cattle populations [0.03%]
PCR-RFLP在阿尔及利亚当地牛群中β乳球蛋白基因的等位基因和基因型频率研究
Nadjet Boushaba,Nacera Tabet-Aoul
Nadjet Boushaba
Milk protein genetic polymorphisms are associated with economically important traits in dairy cattle. The objective of this study is to genotype a single nucleotide polymorphism (SNP) responsible for the amino acid changes in the beta-lacto...
Evaluation of Beclin1 and mTOR genes and p62 protein expression in breast tumor tissues of Iranian patients [0.03%]
伊朗乳腺肿瘤组织中Beclin1和mTOR基因及p62蛋白表达的评估
Maryam Adelipour,Mahshid Naghashpour,Mohammad Reza Roshanazadeh et al.
Maryam Adelipour et al.
Autophagy is a cellular process that plays a major role in the fate of tumor cells. Understanding the role of autophagy in cancer therapy is a major challenge, particularly for breast cancer as the sole top cause of mortality among women. I...
In-silico structural analysis of Heterocephalus glaber amyloid beta: an anti-Alzheimer's peptide [0.03%]
裸吻鼠淀粉样蛋白β的计算机结构分析：一种抗阿尔茨海默氏症的肽
Ali Javanmard,Maryam Azimzadeh-Irani,Ghazal Tafazzoli et al.
Ali Javanmard et al.
Heterocephalus glaber, known as the Naked mole-rat, has an extraordinary immunity to Alzheimer's disease. The pathological hallmark of Alzheimer's disease is cerebral accumulations of plaques, consisting of self-aggregated amyloid beta pept...
A comparison of phylogenetic and distance-based approaches for the distinction of genetically closed species, Draba rimarum (Rech.f.) A.R. Khosravi & A. Eslami-Farouji, and Draba aucheri Boiss. (Brassicaceae) as a case study [0.03%]
以Draba rimarum（Rech.f.）A.R. Khosravi和A. Eslami-Farouji以及Draba aucheri Boiss.（十字花科）为例比较遗传封闭物种的系统发育法与基于距离的方法的区别
Atena Eslami-Farouji,Ahmad Reza Khosravi,Mahdi Gholami et al.
Atena Eslami-Farouji et al.
Circumscribing species boundries is necessary in systematic plant biology. Even a mistake in delimiting taxa may lead to incorrect scientific interpretations. Draba rimarum (Rech.f.) A.R. Khosravi & A. Eslami-Farouji is an endemic Iranian s...
Human BKV large T genome detection in prostate cancer and benign prostatic hyperplasia tissue samples by nested PCR: A case-control study [0.03%]
巢式PCR检测人类BK病毒大型T抗原基因在前列腺癌及良性前列腺增生组织中的表达：病例对照研究
Narges Tavassoli,Arastoo Vojdani,Sara Salimi-Namin et al.
Narges Tavassoli et al.
Human BK polyomavirus (BKPyV) is a latent infectious agent in the genitourinary tract associated with hemorrhagic cystitis and nephropathy. This virus can be a risk factor for various human malignancies, including prostate cancer (PCa). It ...
Сytotoxic effect of CAR-T cells against modified MCF-7 breast cancer cell line [0.03%]
CAR-T细胞对修饰型乳腺癌MCF-7细胞系的细胞毒性效应
Aigul Kh Valiullina,Ekaterina A Zmievskaya,Irina A Ganeeva et al.
Aigul Kh Valiullina et al.
The most often diagnosed and fatal malignancy in women is breast cancer. The International Agency for Research on Cancer (IARC) estimates that there are 2.26 million new cases of cancer in 2020. Adoptive cell therapy using T cells with chim...
Genetic association between rs1695 in glutathione S-transferase P1 and risk of periodontitis: a pilot study [0.03%]
关于谷胱甘肽S-转移酶P1基因多态性与牙周炎遗传易感性的病例对照研究：一项初步报告
Rakshitha Vettri Saravanan,Anitha Pandi,Karthikeyan Murthykumar et al.
Rakshitha Vettri Saravanan et al.
The present study aims to determine the association between a genetic polymorphism of GSTP1 (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of ...