Comparison of Mir122 expression in children with biliary atresia and healthy group [0.03%]
胆道闭锁组与正常对照组外周血中mir-122表达量的对比研究
Nasrin Motazedian,Negar Azarpira,Kimia Falamarzi et al.
Nasrin Motazedian et al.
Biliary atresia (BA) is the primary cause of neonatal jaundice with various pathological mechanisms. Many BA patients may experience progressive liver dysfunction and eventually need a liver transplant. Therefore, identifying potential non-...
Valproic acid and/or rapamycin preconditioning protects hair follicle stem cells from oxygen glucose serum deprivation-induced oxidative injury via activating Nrf2 pathway [0.03%]
丙戊酸和/或雷帕霉素通过激活Nrf2通路保护毛囊干细胞免于氧糖血清剥夺诱导的氧化损伤
Fatemeh Keshavarzi,Mohammad Saied Salehi,Sareh Pandamooz et al.
Fatemeh Keshavarzi et al.
Among leading causes of the ischemic stroke pathogenesis, oxidative stress strongly declines rate of stem cell engraftment at the injury site, and disables stem cell-based therapy as a key treatment for ischemia stroke. To overcome this the...
A survey of resistance mutations to reverse transcriptase inhibitors (RTIs) among HIV-1 patients in northeast of Iran [0.03%]
伊朗东北部HIV-1感染者逆转录酶抑制剂耐药突变调查分析
Zahra Mazaheri,Sahar Tahaghoghi-Hajghorbani,Kazem Baesi et al.
Zahra Mazaheri et al.
The use of a combination of three-drug regimen has improved HIV-1 infected patients' life span and quality; however the emergence of drug-resistant strains remains a main problem. Reverse transcriptase inhibitors (RTIs) consist of a main pa...
The effects of NLRP3 rs10754558 and rs4612666 polymorphisms on preeclampsia susceptibility, onset, and severity: a case-control study and in silico analysis [0.03%]
NLRP3基因多态性与子痫前期易感性、发病及严重程度的关系：病例对照研究和计算机模拟分析
Mahnaz Rezaei,Marzieh Ghasemi,Mohsen Saravani et al.
Mahnaz Rezaei et al.
Preeclampsia (PE) is one of the serious complications of pregnancy and its exact etiology is unknown. Inflammasomes are multiportion complexes whose relation with PE has been described. Evidence showed the effect of NLRP3 inflammasome in PE...
The role of miR-133a in silibinin-mediated inhibition of the PI3K/AKT/mTOR pathway in MCF-7 breast carcinoma cells [0.03%]
白杨素通过miR-133a抑制PI3K/AKT/mTOR信号途径在MCF-7乳腺癌细胞中的作用研究
Mohammadjavad Hossein-Tehrani,Roghayeh Abbasalipourkabir,Nasrin Ziamajidi
Mohammadjavad Hossein-Tehrani
Breast cancer is particularly severe in women. Research highlights the crucial role of miRNAs in key cellular processes, showcasing their intricate interactions with the oncogenic PI3K/AKT/mTOR (PAM) signaling pathway and underscoring their...
Phylogenetic position inferred on SSU rDNA sequence gene and description of a new parasitic cnidarian (Endocnidozoa: Myxobolidae) infecting Markiana nigripinnis (Teleostei: Stevardiinae) from a small marginal lake floodplain, Brazil [0.03%]
基于SSU rDNA序列基因的系统发生位置推断及巴西一小型泛滥湖滨鱼类Markiana nigripinnis（鲈形目：史特凡迪鱼亚科）新寄生刺胞动物（内刺胞动物：黏体虫科）的描述
Maria E B P Mota,Patrik D Mathews,Tiago Milanin et al.
Maria E B P Mota et al.
Herein, a detailed molecular phylogeny analysis was developed to determine the phylogenetic position of a new freshwater histozoic myxosporean cnidarian, Henneguya markiana sp. nov. from the world's largest tropical wetland area, Pantanal, ...
S A Smiline Girija
S A Smiline Girija
Epigenetic mechanisms attribute to the resistance and virulence of Acinetobacter baumannii sparking a renewed area of research. Unveiling the targets pertained to the epigenetic modulation in the bacterium would aid in the curbing its compl...
The effects of thymidylate synthase 3'UTR genotype on methylation of tumor-specific genes promoter in 22 colorectal cancer patients from southern Iran [0.03%]
叶酸代谢关键酶基因多态性对22例南方伊朗结直肠癌患者发生影响的研究及其机理探讨
Maryam Niknam,Fakhraddin Naghibalhossaini,Mozhdeh Zamani et al.
Maryam Niknam et al.
To investigate the effects of thymidylate synthase (TS) 3'UTR genotype on promotor methylation of tumor-related genes in 22 patients with sporadic colorectal cancer (CRC) from southern Iran. We evaluated the correlations of TS 3'UTR genotyp...
Association study of the polymorphisms rs2228611 of the DNMT1 gene and rs1569686 of the DNMT3B gene with bladder cancer development in a sample of the Algerian population [0.03%]
阿尔及利亚人群DNA甲基转移酶基因多态性与膀胱癌关联研究
Zohra Touala-Chaila,Rym-Khadidja Abderrahmane,Slimane Kerroumi et al.
Zohra Touala-Chaila et al.
Bladder cancer (BC) is a multifactorial disease with a poorly understood main cause. In this study, we aimed to evaluate the effect of the polymorphisms rs2228611 of the DNMT1 gene and rs1569686 of the DNMT3B gene on the susceptibility to d...
Examining the expression of low-density lipoprotein receptor (LDLR) and low-density lipoprotein receptor-related protein 6 (LRP6) genes in breast cancer cell lines [0.03%]
乳腺癌细胞系中低密度脂蛋白受体(LDLR)和低密度脂蛋白相关受体6(LRP6)基因的表达研究
Hamid Behrouj,Mehran Erfani,Pooneh Mokarram
Hamid Behrouj
Cholesterol and the Wnt/β-catenin pathway have an effective role in the proliferation, survival, drug resistance, immune exhaustion, and metastasis of all types of cancer cells. Considering the role of LDLR and LRP6 proteins in cholesterol...