Comparison of inflammatory molecular mechanisms between osteoarthritis and rheumatoid arthritis via gene microarrays [0.03%]
基于基因芯片的骨关节炎与类风湿关节炎炎症分子机制比较研究
Maziar Oveisee,Akram Gholipour,Mahshid Malakootian
Maziar Oveisee
Osteoarthritis (OA) and rheumatoid arthritis (RA) treatment requires exact arthritis type diagnosis. We compared inflammatory molecular mechanisms between OA and RA to introduce reliable molecular biomarkers. The GSE55235 and GSE100786 micr...
A comprehensive in silico analysis of mutation spectrum of maple syrup urine disease (MSUD) genes in Iranian population [0.03%]
伊朗人群 Maple Syrup Urine 疾病基因突变谱的全面计算分析研究
Nahid Rezaie,Saeedeh Sadat Ghazanfari,Teymoor Khosravi et al.
Nahid Rezaie et al.
Maple syrup urine disease (MSUD) represents an infrequent metabolic disease precipitated by an insufficiency of the enzymatic complex known as branched-chain alpha-keto acid dehydrogenase. MSUD can be classified as classic (severe), interme...
Negar Tafvizi,Mandana Behbahani,Hassan Mohabatkar
Negar Tafvizi
L-asparaginase is a commercial enzyme with a wide variety of applications. Asparaginase is known as an anti-cancer agent that is effective for the treatment of certain lymphomas and leukemias by growth inhibition of human cancer cells. Addi...
Association between rs3761548 polymorphism of FOXP3 and the risk of gastric cancer: a case-control study [0.03%]
FOXP3基因rs3761548多态性与胃癌发病风险的关联研究：病例对照研究
Shamimeh Validi,Iraj Saadat
Shamimeh Validi
Gastric cancer is one of the most prevalent malignancies in the world. Various factors play a role in the development of this disease as risk factors. One of these genes is the FOXP3, which is located on the short arm of the X chromosome (X...
In silico analysis for SARS-CoV-2 detection in the context of genetic variability of the Algerian omicron variant [0.03%]
基于阿尔及利亚omicron变异株遗传变异的SARS-CoV-2检测的计算机分析
Chahinez Amira Dahmani,Asmaa Azzoune,Abdallah Boudjema
Chahinez Amira Dahmani
The risk to public health conferred by the Omicron variant is still not completely clear, although its numerous gene mutations have raised concerns regarding its potential for increased transmissibility and immune escape. In this study, we ...
The hepatoprotective effects of sitagliptin against cyclophosphamide-induced hepatotoxicity in rat [0.03%]
西格列汀对环磷酰胺致大鼠肝毒性保护作用研究
Reza Maleki,Mohammad Foad Noorbakhsh,Nasrin Kazemipour et al.
Reza Maleki et al.
Hepatotoxicity is a serious side effects of cyclophosphamide. Thus, the present research investigates the protective properties of sitagliptin against cyclophosphamide-induced hepatotoxicity. Fifty male rats were randomly divided into five ...
Genome-wide mining and characterization of MATE transporters in Coriandrum sativum L [0.03%]
Coriandrum sativum L.中MATE转运蛋白的全基因组鉴定及特征分析
Deepu Mathew,Ravisankar Valsalan,M Shijili
Deepu Mathew
Multidrug and Toxic Compound Extrusion (MATE) proteins are responsible for the transport of a wide range of metabolites out of plant cells. This helps to protect the cells from toxins and other harmful compounds. MATE proteins also play a r...
Natural compounds solasonine and alisol B23-acetate target GLI3 signaling to block oncogenesis in MED12-altered breast cancer [0.03%]
天然化合物溶声碱和猪殃殃素B23-乙酸酯通过靶向GLI3信号轴抑制MED12改变的乳腺癌的发生发展
Shivani Akula,Cristian G Gonzalez,Sophia Kermet et al.
Shivani Akula et al.
Breast cancer remains to be the second leading cause of cancer deaths worldwide thereby highlighting the critical need to find superior treatment strategies for this disease. In the current era of cancer treatment, personalized medicine is ...
Effects of silymarin as adjuvant drug on serum levels of CTRP3, anti-cyclic citrullinated peptide (CCP), and high-sensitivity C-reactive protein (hs-CRP) in rheumatoid arthritis patients [0.03%]
水飞蓟宾作为联合用药对类风湿关节炎患者血清CTRPS1、抗环瓜氨酸肽抗体及高敏C-反应蛋白水平的影响
Mohammad Ehsan Elahi,Daniel Elieh-Ali-Komi,Farjam Goudarzi et al.
Mohammad Ehsan Elahi et al.
Silymarin is known for its anti-inflammatory and antioxidant properties. We investigated these effects on serum levels of CTRP3, Anti-CCP, and hs-CRP in individuals with Rheumatoid arthritis (RA). In this study, 42 individuals with RA were ...
Clinical profile of FTL3-ITD mutation in West Algerian population with acute myeloid leukemia [0.03%]
西阿尔及利亚急性髓系白血病患者FTL3-ITD基因突变的临床特征分析
Fatima Zohra Moghtit,Wefa Boughrara,Samia Dorgham et al.
Fatima Zohra Moghtit et al.
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the abnormal and rapid growth of cells. The mutation of the Fms-like tyrosine kinase 3 ligand gene (FLT3-ITD) represents an important factor in th...