HIV-1 reverse transcriptase subtyping revealed CRF35-AD as a current subtype in the northeast of Iran [0.03%]
HIV-1逆转录酶亚型分类显示CRF35-AD是伊朗东北部当前的亚型
Zahra Mazaheri,Masoud Youssefi
Zahra Mazaheri
Previously, the sequence of the HIV-1 reverse transcriptase gene was analyzed to identify mutations associated with drug resistance. We statistically analyzed the relationship between a set of additional data and increasing mutations. Exist...
Comprehensive computational analysis of deleterious nsSNPs in PTEN gene for structural and functional insights [0.03%]
PTEN基因有害nsSNPs的全面计算分析以获得结构和功能见解
Divyanshi Sharma,Harasees Singh,Aryan Arya et al.
Divyanshi Sharma et al.
Single nucleotide polymorphisms (SNPs) are pivotal in understanding the genetic basis of complex disorders. Among them, nonsynonymous SNPs (nsSNPs) that alter amino acid sequences can significantly impact protein structure and function. Thi...
Jayaseelan Vijayashree Priyadharsini,Anitha Pandi
Jayaseelan Vijayashree Priyadharsini
Diabetes mellitus has been linked to an increased risk of oral cancer, with hyperglycemia and chronic inflammation contributing to malignant transformation. Accumulating evidence has highlighted the role of specific genes and biomarkers ass...
Effect of 30-day Ramadan fasting on autophagy pathway and metabolic health outcome in healthy individuals [0.03%]
为期30天的Ramadan禁食对健康个体自噬途径和代谢健康结果的影响
Sanaz Dastghaib,Morvarid Siri,Nasim Rahmani-Kukia et al.
Sanaz Dastghaib et al.
During Ramadan, Muslims fast to spiritually prepare their bodies and spirits. The autophagy pathway restores cellular homeostasis and is being studied as a therapy for a variety of disorders. According to previous studies, fasting or calori...
Pathogenic variants of BUB1 and BUBR1 genes are not prioritized in screening tests of couples with aborted aneuploid fetuses [0.03%]
患病的BUB1和BUBR1基因在流产夫妇的筛查测试中不会优先考虑
Raziyeh Gorji,Parnaz Borjian-Boroujeni,Masood Bazrgar
Raziyeh Gorji
Chromosome aberrations certainly aneuploidie are the cause of the majority of spontaneous abortions in humans. BUB1 (budding uninhibited by benzimidazole 1) and BUBR1 (BUB1 mitotic checkpoint serine/threonine kinase B) are two key proteins ...
Computational analysis of Ayurvedic herbs to explore their potential role as anti-cervical cancer agents [0.03%]
计算分析传统草药以探索其作为抗宫颈癌药物的潜在作用
Suhani Dange,Neha Aggarwal,Rivi Verma et al.
Suhani Dange et al.
Cervical cancer is one of the common types of cancer in women. Treatment regimens include use of chemotherapy but it leads to certain side effects thereby creating a need for safer therapeutic options. Ayurveda has a great potential to prov...
Clinical relevance of plasma-derived exosomal long non-coding RNAs (lncRNAs) CCAT1 and XIST in colorectal cancer patients [0.03%]
血浆来源的长链非编码RNA（lncRNA）CCAT1和XIST在结直肠癌患者中的临床意义
Fatemeh Dana,Soleiman Mahjoub,Zahra Shokati Eshkiki et al.
Fatemeh Dana et al.
The expression level of exosomal long non-coding RNAs (lncRNAs) can be relevant for clinical diagnostic approaches. The object of our study was to evaluate the differential expression of lncRNAs colon cancer associated transcript 1 (CCAT1) ...
Nasim Rahmani-Kukia,Fatemeh Keshavarzi,Mohammad Saied Salehi et al.
Nasim Rahmani-Kukia et al.
Human Epidermal Neural Crest Stem Cells (hEPI-NCSCs), as a transient population of multipotent migratory stem cells can differentiate into multiple types of neural and non-neural cells and tissues in the body. Here, we tried to determine th...
Investigation methylation status of tumor suppressor gene NR4A1 and NR4A3 and frequency of rs1569686 polymorphism of DNMT3B gene in patients with acute myeloid leukemia [0.03%]
急性髓系白血病患者抑癌基因NR4A1和NR4A3的甲基化状态及DNMT3B基因rs1569686多态性的频率研究
Baharan Rahmani,Shahrbano Rostami,Yousef Mortazavi et al.
Baharan Rahmani et al.
Acute myeloid leukemia (AML) is the most frequent type of leukemia among adults. Investigating AML heterogeneity based on DNA methylation can improve clinical diagnosis and prognosis. This study was conducted to investigate NR4A1 and NR4A3 ...