In silico analysis of suitable signal peptides for secretion of a recombinant alcohol dehydrogenase with a key role in atorvastatin enzymatic synthesis [0.03%]
用于阿托伐他汀酶法合成关键酶重组醇脱氢酶分泌的信号肽的计算机分析
Mortaza Taheri-Anganeh,Seyyed Hossein Khatami,Zeinab Jamali et al.
Mortaza Taheri-Anganeh et al.
An elevated cholesterol level might lead to cardiovascular disease (CVD). Statins block the cholesterol synthesis pathway in the liver. Atorvastatin is the most widespread statin worldwide and, its chemical synthesis requires toxic catalyst...
Baoyan Jia,Xinhua Zhao,Yang Qin et al.
Baoyan Jia et al.
In this study 90 individuals of recombinant inbred lines (RILs) were developed by crossing subspecies of japonica rice cultivar, 'Nagdong' and an indica type cultivar, 'Cheongcheong'. These individuals were used to identify the quantitative...
The 40bp indel polymorphism of MDM2 increase the risk of cancer: An updated meta-analysis [0.03%]
MDM2基因40bp插入/缺失多态性增加肿瘤发病风险的meta分析
Abdolkarim Moazeni-Roodi,Saeid Ghavami,Mohammad Hashemi
Abdolkarim Moazeni-Roodi
This meta-analysis aimed to provide an up-to-date comprehensive evaluation on the association between the MDM2 40bp indel polymorphism and cancer susceptibility. Eligible studies were retrieved by searching Web of Science, PubMed, Scopus, a...
Effects of associated SCF and G-CSF on liver injury two weeks after liver damage: A model induced by thioacetamide administration [0.03%]
两周硫代乙酰胺致肝损伤后联合应用SCF和G-CSF对肝脏的影响模型研究
Mohsen Esmaili,Durdi Qujeq,Ali Asghar Yoonesi et al.
Mohsen Esmaili et al.
The present study aimed at investigating the beneficial effects of co-administering granulocyte colony-stimulating factor (G-CSF) and stem cell factor (SCF) in a model of chronic liver injury induced by thioacetamide (TAA). Biochemical and ...
Heavy metal regulation of plasma membrane H+-ATPase gene expression in halophyte Aeluropus littoralis [0.03%]
重金属对盐生植物海滨棒头草质膜H+-ATP酶基因表达的调控作用研究
Mohsen Jam,Abbas Alemzadeh,Ali Mohammad Tale et al.
Mohsen Jam et al.
The present study was conducted to find the effect of three heavy metals, Ag, Hg and Pb on the expression level of a gene encoding plasma membrane H+-ATPase in Aeluropus littoralis. The experiment was laid out in a completely random design ...
Designing and analyzing the structure of Tat-BoNT/A(1-448) fusion protein: An in silico approach [0.03%]
Tat-BoNT/A(1-448)融合蛋白结构的设计与分析：一种基于计算机模拟的方法
Jafar Amani,Parvaneh Saffarian,Shahin Najar-Peerayeh et al.
Jafar Amani et al.
Clostridium botulinum type A (BoNT/A) produces a neurotoxin recently found to be useful as an injectable drug for the treatment of abnormal muscle contractions. The catalytic domain of this toxin which is responsible for the main toxin acti...
A tri state mechanism for oxygen release in fish hemoglobin: Using Barbus sharpeyi as a model [0.03%]
一种鱼类血红蛋白释放氧气的三稳态机制——以巴巴士鱼为模型物种的研究
Mohammad Reza Dayer,Mohammad Saaid Dayer,Ali Akbar Moosavi-Movahedi
Mohammad Reza Dayer
Hemoglobin is a porphyrin containing protein with an α2β2 tetrameric structure and like other porphyrin compounds shows spectral behavior of species specific characteristics. Researchers tend to relate bands in the hemoglobin spectra to c...
Analysis of nitrate reductase mRNA expression and nitrate reductase activity in response to nitrogen supply [0.03%]
硝态氮供应对小麦根冠硝酸盐还原酶活性及mRNA表达的影响分析
Gholamreza Kavoosi,Sadegh Balotf,Homeira Eshghi et al.
Gholamreza Kavoosi et al.
Nitrate is one of the major sources of nitrogen for the growth of plants. It is taken up by plant roots and transported to the leaves where it is reduced to nitrite in the. The main objective of this research was to investigate stimulatory ...
Screening of CYP1B1 Arg368His as predominant mutation in North Indian primary open angle glaucoma and juvenile onset glaucoma patients [0.03%]
原发性开角型青光眼和青少年型青光眼中北印度人CYP1B1基因Arg368His突变为主要类型的研究
Avneet Kaur,Vanita Vanita,JaiRup Singh
Avneet Kaur
In India, mutations in Cytochrome P450 (CYP1B1) are a predominant cause of not only primary congenital glaucoma (PCG) but also involved in primary open angle glaucoma (POAG) and juvenile onset glaucoma (JOAG). After ethical clearance, 100 P...
Association study between DNA methylation and genetic variation of APOE gene with the risk of coronary artery disease [0.03%]
APOE基因DNA甲基化和遗传变异与冠心病风险的关联研究
Habib Ghaznavi,Ali Asghar Kiani,Mohammad Soleiman Soltanpour
Habib Ghaznavi
Coronary artery disease (CAD) is a common health problem with a high rate of disability and death. Dyslipidemia and altered metabolism of Apo-lipoproteins are involved in the CAD pathogenesis. The current study investigated two common polym...