Genetic diversity analysis and population structure of some Iranian Fenugreek (Trigonella foenum-graecum L.) landraces using SRAP Markers [0.03%]
基于SRAP标记的伊朗几种香荚蒾地方品种遗传多样性分析及群体结构研究
Marzieh Amiriyan,Abdolali Shojaeiyan,Abbas Yadollahi et al.
Marzieh Amiriyan et al.
Fenugreek is one of the important edible and medicinal vegetables that have a long history of cultivation and consumption. Characterize the extent of the genetic diversity among landraces will provide a good context for future breeding prog...
Hossein Pourghadamyari,Mohammad Rezaei,Ali Ipakchi-Azimi et al.
Hossein Pourghadamyari et al.
Skeletal muscle injuries are one of the most common problems in the worldwide which impose a substantial financial burden to the health care system. Accordingly, it widely accepted that muscle regeneration is a promising approach that can b...
Insertion/deletion polymorphism of angiotensin-converting enzyme and chronic obstructive pulmonary disease: A case-control study on north Indian population [0.03%]
血管紧张素转换酶的插入/缺失多态性与慢性阻塞性肺疾病：一项针对印度北部人群的病例对照研究
Nikhil Kirtipal,Hitender Thakur,Ranbir Chander Sobti
Nikhil Kirtipal
This research aimed to explore the ACE (insertion/deletion) gene association as key factor for chronic obstructive pulmonary disease (COPD) development in north Indian population. A total of 200 clinically diagnosed patients with COPD were ...
Screening of LEP gene polymorphisms as a risk factor for obesity and type 2 diabetes in Iraqis [0.03%]
LEP基因多态性在伊拉克人肥胖和2型糖尿病风险评估中的作用筛查
Maysoon Khudheyer Almyah,Adnan Issa Albadran
Maysoon Khudheyer Almyah
The prevalence of obesity and diabetes changes dramatically with lifestyle and unequal risk among individuals have made scientists interested to understand how the environment interferes with genetic factors to make it so-called genetic pre...
LytU-SH3b fusion protein as a novel and efficient enzybiotic against methicillin-resistant Staphylococcus aureus [0.03%]
LytU-SH3b融合蛋白作为抗万古霉素耐药金黄色葡萄球菌的新型和高效的酶源性抗菌素的研究
Mortaza Taheri-Anganeh,Seyyed Hossein Khatami,Zeinab Jamali et al.
Mortaza Taheri-Anganeh et al.
Methicillin-resistant Staphylococcus aureus (MRSA) is a challenging infectious agent worldwide. The ever growing antibiotic resistance has made the researchers to look for new anti-staphylococcal agents. Autolysins are staphylococcal enzyme...
In silico analysis for determining the deleterious nonsynonymous single nucleotide polymorphisms of BRCA genes [0.03%]
BRCA基因有害非同义单核苷酸多态性的生物信息学分析
Fatemeh Yadegari,Keivan Majidzadeh
Fatemeh Yadegari
Recent advances in DNA sequencing techniques have led to an increase in the identification of single nucleotide polymorphisms (SNPs) in BRCA1 and BRCA2 genes, but no further information regarding the deleterious probability of many of them ...
APOE4 allele in north Indian elderly patients with dementia or late onset depression-a multiple-disease case control study [0.03%]
apoε4基因与印度北部老年人认知障碍和晚发性抑郁的关联：多病种病例对照研究
Anamika Misra,Sankha Shubhra Chakrabarti,Indrajeet Singh Gambhir et al.
Anamika Misra et al.
The objective of the study was to analyze the frequency of APOE4 allele in elderly patients with Alzheimer's or vascular dementia or depression; compare these to age/sex matched controls; compare the results with established literature and ...
Debasish Malik,Utpal Basu
Debasish Malik
Mutation in the dystrophin gene results Duchenne Muscular Dystrophy (DMD), an X-linked fatal neuromuscular disorder. Dystrophin deficiency can be compensated by upregulation of utrophin, an autosomal homologue of dystrophin. But the express...
Novel Isatin-based activator of p53 transcriptional functions in tumor cells [0.03%]
一种异鼠李素衍生物通过激活p53转录功能发挥抗癌作用
Regina Mirgayazova,Raniya Khadiullina,Rimma Mingaleeva et al.
Regina Mirgayazova et al.
Bioinorganic medicinal chemistry remains a hot field for research aimed at developing novel anti-cancer treatments. Discovery of metal complexes as potent antitumor chemotherapeutics such as cisplatin led to a significant shift of focus tow...
Functional investigation of the BRCA1 Val1714Gly and Asp1733Gly variants by computational tools and yeast transcription activation assay [0.03%]
计算工具和酵母转录激活测定对BRCA1 Val1714Gly 和Asp1733Gly变异的功能研究
Fatemeh Yadegari,Leila Farahmand,Rezvan Esmaeili et al.
Fatemeh Yadegari et al.
Mutations in the BRCA1 gene are known to be a major cause of hereditary breast cancer. However, characterizing the point mutations associated with cancer in BRCA1 is challenging because the functional impact of most of them is still unknown...