In silico analyzing the molecular interactions of plant-derived inhibitors against E6AP, p53, and c-Myc binding sites of HPV type 16 E6 oncoprotein [0.03%]
基于计算机分析植物来源的抑制剂与HPV16 E6癌蛋白p53和c-Myc结合位点的分子相互作用研究
Farzan Nabati,Mohammad Moradi,Hassan Mohabatkar
Farzan Nabati
Human papillomaviruses (HPV) are a group of strong human carcinogen viruses considered to be the fourth leading cause of mortality among women in the world. HPV is the most important cause of cervical cancer, which is the second most common...
Computational approach towards identification of pathogenic missense mutations in AMELX gene and their possible association with amelogenesis imperfecta [0.03%]
计算方法识别AMELX基因中的致病错义突变及其与成釉不全的可能关联
Narendra Shivani,Aseervatham Selvi Smiline-Girija,Arumugam Paramasivam et al.
Narendra Shivani et al.
Amelogenin gene (AMEL-X) encodes an enamel protein called amelogenin, which plays a vital role in tooth development. Any mutations in this gene or the associated pathway lead to developmental abnormalities of the tooth. The present study ai...
Production of transgenic Paulownia tomentosa (Thunb.) steud. using chitosan nanoparticles to express antimicrobial genes resistant to bacterial infection [0.03%]
使用壳聚糖纳米颗粒表达抗细菌感染的抗菌基因以生成转基因 paulownia tomentosa (thunb.) steud.
Eman Tawfik Hussien
Eman Tawfik Hussien
Paulownia tomentosa (Thunb.) Steud. is a very important hard woody plant, an extremely fast-growing tree and produce timber. Therefore, there is a demand to produce transgenic Paulownia plant resistant to bacterial infection. Microbial infe...
Molecular characterization and DNA methylation profile of Libyodrilus violaceous from oil polluted soil [0.03%]
来自石油污染土壤的紫红利比亚 Drake 钻杆虫的分子特征和DNA甲基化分布概貌
Aemere Ogunlaja,Vikas Sharma,Meenu Ghai et al.
Aemere Ogunlaja et al.
Studies on earthworms using molecular markers are rare in Africa except a handful from South Africa. Reports on Libyodrilus violaceous, an earthworm found in West Africa are available including their metal tolerance and bioaccumulation capa...
Association between IL6 gene polymorphism and the risk of chronic obstructive pulmonary disease in the north Indian population [0.03%]
IL6基因多态性与北印度人群慢性阻塞性肺疾病风险的关联分析
Nikhil Kirtipal,Hitender Thakur,Ranbir Chander Sobti et al.
Nikhil Kirtipal et al.
Interleukin-6 (IL6) is encoded by the IL6 gene in human and acts as pro-inflammatory cytokine and an anti-inflammatory cytokine. Recent studies established that IL6 substantially contribute in the diagnosed of systemic inflammation for the pa...
Association study between rs2275913 genetic polymorphism and serum levels of IL-17A with risk of coronary artery disease [0.03%]
rs2275913基因多态性与IL-17A血清水平及冠心病发病风险的相关性研究
Habib Ghaznavi,Mohammad Soleiman Soltanpour
Habib Ghaznavi
Coronary artery disease (CAD) is now considered as a main cause of disability and mortality in Iranian population. Inflammatory processes are the initial events in the development of CAD. Interleukin-17A (IL-17A) is a pro-inflammatory cytok...
Production of phenolic acids in hairy root cultures of medicinal plant Mentha spicata L. in response to elicitors [0.03%]
植物根毛培养生产酚酸类化合物响应次生代谢产物诱导剂的效果研究-以薄荷为例
Shirin Yousefian,Tahmineh Lohrasebi,Mohsen Farhadpour et al.
Shirin Yousefian et al.
In this study, hairy root induction in leaf and stem explants of Mentha spicata using various Agrobacterium rhizogenes strains was established for the first time. Although inoculation of explants by immersion method resulted in tissue necro...
Molecular detection of Mycobacterium leprae using RLEP-PCR in post elimination era of leprosy [0.03%]
后麻风病消除时代麻风分枝杆菌的RLEP基因座PCR检测技术研究
Partha Sarathi Mohanty,Farhah Naaz,Avi Kumar Bansal et al.
Partha Sarathi Mohanty et al.
Leprosy is considered as a contagious disease and is still a health problem in several countries including India. Diagnosis of leprosy is based either on clinical findings or on acid fast bacilli staining. Due to low sensitivity of acid fas...
Genetic polymorphisms of Y-chromosome short tandem repeats (Y-STRs) in a male population from Golestan province, Iran [0.03%]
伊朗戈勒斯坦省男性人口Y染色体短串联重复序列（Y-STR）多态性分布研究
Minoo Sayyari,Ali Salehzadeh,Mohammad Amin Tabatabaiefar et al.
Minoo Sayyari et al.
Short Tandem Repeats (STRs), which are located out of pseudo-autosomal parts of the human Y chromosome and passed-down from fathers to the male offspring in a non-recombinant form, are regarded as appropriate markers for forensic purposes a...
Analyzing Signal Peptides for Secretory Production of Recombinant Diagnostic Antigen B8/1 from Echinococcus granulosus: An In silico Approach [0.03%]
基于计算方法分析细粒棘球绦虫重组诊断抗原B8/1分泌表达信号肽
Seyyed Hossein Khatami,Mortaza Taheri-Anganeh,Farzane Arianfar et al.
Seyyed Hossein Khatami et al.
Recombinant AgB8/1 as the most evaluated antigen for serological diagnosis of Cystic Echinococcosis (CE) can provide early and accurate diagnosis for proper management and treatment of the disease. Thus, the secretory production of this rec...