MiR-200c-3p expression may be associated with worsening of the clinical course of patients with COVID-19 [0.03%]
MiR-200c-3p的表达可能与COVID-19患者的临床病程恶化相关
Ruan Pimenta,Nayara I Viana,Gabriel A Dos Santos et al.
Ruan Pimenta et al.
COVID-19 represents a public health emergency, whose mechanism of which is not fully understood. It is speculated that microRNAs may play a crucial role in host cells after infection by SARS-CoV-2. Thus, our study aimed to analyze the expre...
In silico identification of promising inhibitor against RNA-dependent RNA polymerase target of SARS-CoV-2 [0.03%]
计算识别SARS-CoV-2复制酶(NRP)蛋白的潜在抑制剂
Pushpendra Singh,Manish Kumar Tripathi,Mohammad Yasir et al.
Pushpendra Singh et al.
The severe acute respiratory syndrome is a viral respiratory disease recognised as COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Formerly, no precise remedies are available, and many studies regarding COV...
Telomeric zinc-finger associated protein (TZAP) in cancer biology: friend or foe? [0.03%]
端粒C末端结合蛋白(TZAP)在癌症生物学中的作用：是敌是友？
Gabriel Arantes Dos Santos,Nayara Izabel Viana,Ruan Pimenta et al.
Gabriel Arantes Dos Santos et al.
The new identified protein telomeric zinc-finger associated protein (TZAP) is a negative regulator of telomere length. Since telomere length and telomere maintenance mechanisms are essential to cancer progression, TZAP is considered a new p...
Role of SALL4 and Nodal in the prognosis and tamoxifen resistance of estrogen receptor-positive breast cancer [0.03%]
SALL4和Nodal在雌激素受体阳性乳腺癌预后及托瑞米芬耐药中的作用
Arad Boustan,Fatemeh Mosaffa,Rosa Jahangiri et al.
Arad Boustan et al.
Despite the discovery of a number of different mechanisms underlying tamoxifen resistance, its molecular pathway is not completely clear. The upregulation of SALL4 and Nodal has been reported in breast cancer. Nevertheless, their role in ta...
Prokaryotic expression of chimeric GFP-hFc protein as a potential immune-based tool [0.03%]
作为潜在的免疫学工具的融合了GFP的hFc蛋白的原核表达
Thanh-Tan Nguyen,Hai-Vy Vo-Nguyen,Hieu Tran-Van
Thanh-Tan Nguyen
GFP is an old-yet-powerful protein marker, which has been widely used in molecular biotechnology due to its capacity of exhibiting bright green fluorescence when exposed to ultraviolet light. The hFc region of IgG antibodies is a specific b...
In vitro osteogenic induction of human adipose stem cells co-treated with betaine/osteogenesis differentiation medium [0.03%]
甜菜碱与骨诱导分化培养基共处理对人脂肪干细胞体外成骨诱导的影响
Tayebeh Sadat Tabatabai,Maryam Haji-Ghasem-Kashani,Meysam Nasiri
Tayebeh Sadat Tabatabai
Human adipose-derived stem cells (hADSCs) are widely used in regenerative medicine and affected by many biochemical and biophysical stimuli in vivo. Betaine has been reported to be a type of osteogenic stimulating biochemical factor. This s...
Enhanced inulin production by hairy root cultures of Cichorium intybus in response to Pi and Fe starvation [0.03%]
磷和铁缺乏对刺激菊芋毛状根培养体系中果糖的影响
Somayeh Tabatabaee,Forough Sanjarian,Tahmineh Lohrasebi et al.
Somayeh Tabatabaee et al.
Cichorium intybus is rich in inulin and has several pharmacological applications. Hairy roots culture is a valuable biotechnological tool used to produce plant secondary metabolites. Agrobacterium rhizogenes-mediated genetic transformation ...
Abundance of antibiotic resistance genes in bacteria and bacteriophages isolated from wastewater in Shiraz [0.03%]
设拉子废水中的细菌和噬菌体中抗生素抗性基因的丰度
Sahar Zare,Abdollah Derakhshandeh,Ali Mohammadi et al.
Sahar Zare et al.
Generally, the high widespread presence of antimicrobial resistance, and the next freeing into aquatic environments which provide a situation for transmission of these genes in water is because of the abuse of the antimicrobial drugs in bot...
Cloning and expressing of interleukine 2 in amniotic membrane-derived mesenchymal stem cells, as a potent feeder layer [0.03%]
从羊膜中分离培养的间充质干细胞的IL-2基因克隆及表达研究
Saeid Anvari,Farshad Foroughi,Mehdi Azad et al.
Saeid Anvari et al.
The application of mesenchymal stem cells (MSCs) is rapidly expanding due to their unique properties in cell therapy, especially as the feeder layer in the ex-vivo expansion of immune cells. Also, Interleukin 2 (IL-2) is an essential human ...
Experimental validation of a predicted microRNA within human FVIII gene [0.03%]
人F8基因中预测的microRNA的实验验证
Shahabeddin Jalali-Qomi,Majid Motovali-Bashi,Halimeh Rezaei et al.
Shahabeddin Jalali-Qomi et al.
Hemophilia A is an X-linked bleeding disorder that occurs due to the deficiency of Factor VIII (FVIII) protein clotting activity. The mutations in the F8 gene, which encodes FVIII coagulating protein have been widely reviewed. However, ther...