TRPV1 nociceptors are required to optimize antigen-specific primary antibody responses to novel antigens [0.03%]
TRPV1伤害性感觉器对于优化新型抗原的特异性初次抗体应答是必需的
Aisling Tynan,Téa Tsaava,Manojkumar Gunasekaran et al.
Aisling Tynan et al.
Background: Key to the advancement of the field of bioelectronic medicine is the identification of novel pathways of neural regulation of immune function. Sensory neurons (termed nociceptors) recognize harmful stimuli and...
Unintentionally intentional: unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury [0.03%]
脊髓损伤后电刺激疗法的非预期效应及其在多模式神经康复中的应用价值
Gerson N Moreno Romero,Avery R Twyman,Maria F Bandres et al.
Gerson N Moreno Romero et al.
Electrical stimulation of spinal neurons has emerged as a valuable tool to enhance rehabilitation after spinal cord injury. In separate parameterizations, it has shown promise for improving voluntary movement, reducing symptoms of autonomic...
Using nonlinear auto-regressive with exogenous input neural network (NNARX) in blood glucose prediction [0.03%]
基于非线性自回归投入神经网络的血糖预测模型研究
Fayrouz Allam
Fayrouz Allam
Background: Predicting of future blood glucose (BG) concentration is important for diabetes control. Many automatic BG monitoring or controlling systems use BG predictors. The accuracy of the prediction for long predictio...
Evaluation of the EMulate Therapeutics Voyager's ultra-low radiofrequency energy in murine model of glioblastoma [0.03%]
EMulate Therapeutics Voyager的超低无线电能在胶质母细胞瘤小鼠模型中的评估研究
Rajesh Mukthavaram,Pengfei Jiang,Sandra Pastorino et al.
Rajesh Mukthavaram et al.
Background: Glioblastoma (GBM) presents as an aggressive brain cancer, notorious for its recurrence and resistance to conventional treatments. This study aimed to assess the efficacy of the EMulate Therapeutics Voyager®,...
A novel neuroimmune modulation system for the treatment of rheumatoid arthritis [0.03%]
治疗类风湿性关节炎的新型神经免疫调节系统
Bruno Bonaz
Bruno Bonaz
The vagus nerve has an anti-inflammatory effect through the inflammatory reflex, which inhibits the release of proinflammatory cytokines by macrophages. Recent pilot clinical trials, using implantable bioelectronic devices, have demonstrate...
Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study [0.03%]
新型可植入神经免疫调节装置治疗类风湿性关节炎的临床安全性和可行性：随机、双盲、假手术对照的RESET-RA研究的初步结果
Daniel Peterson,Mark Van Poppel,Warren Boling et al.
Daniel Peterson et al.
Background: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that causes persistent synovitis, bone damage, and progressive joint destruction. Neuroimmune modulation through electrical stimulation of...
Harnessing metamaterials for efficient wireless power transfer for implantable medical devices [0.03%]
利用超材料提高植入式医疗设备的无线传电效率
Sultan Mahmud,Ali Nezaratizadeh,Alfredo Bayu Satriya et al.
Sultan Mahmud et al.
Wireless power transfer (WPT) within the human body can enable long-lasting medical devices but poses notable challenges, including absorption by biological tissues and weak coupling between the transmitter (Tx) and receiver (Rx). In pursui...
Microfluidic compartmentalization of rat vagal afferent neurons to model gut-brain axis [0.03%]
用于模拟脑肠轴的_rat_迷走传入神经元的微流控隔室化技术
Gregory Girardi,Danielle Zumpano,Helen Raybould et al.
Gregory Girardi et al.
Background: Vagal afferent neurons represent the key neurosensory branch of the gut-brain axis, which describes the bidirectional communication between the gastrointestinal system and the brain. These neurons are importan...
A soft, scalable and adaptable multi-contact cuff electrode for targeted peripheral nerve modulation [0.03%]
一种柔软、可扩展且适用于靶向周围神经调节的多接触袖状电极
Valentina Paggi,Florian Fallegger,Ludovic Serex et al.
Valentina Paggi et al.
Background: Cuff electrodes target various nerves throughout the body, providing neuromodulation therapies for motor, sensory, or autonomic disorders. However, when using standard, thick silicone cuffs, fabricated in disc...
McGregor Joyner,Sheng-Hsiou Hsu,Stephanie Martin et al.
McGregor Joyner et al.
Background: Seizure detection is challenging outside the clinical environment due to the lack of comfortable, reliable, and practical long-term neurophysiological monitoring devices. We developed a novel, discreet, unobst...