Continuous vs. intermittent chronic vagus nerve stimulation: effects on T-cell dependent antibody response, heart rate variability and body weight in immunized mice [0.03%]
连续和间歇慢性迷走神经刺激对免疫小鼠T细胞依赖性抗体反应、心率变异性及体重的影响
Michael Gerber,Ibrahim Mughrabi,Izumi Kurata-Sato et al.
Michael Gerber et al.
Vagal-immune interactions are increasingly recognized to play a role in the pathogenesis of diseases associated with immune dysfunction. To study the direct effects of altered vagal activity on adaptive immune function and antibody producti...
Autonomic and neural responses to varying transcutaneous cervical electrical stimulation parameters [0.03%]
不同经皮颈神经电刺激参数的自主和神经反应
Shubham Debnath,Fylaktis Fylaktou,Blake T Gurfein et al.
Shubham Debnath et al.
Background: Transcutaneous cervical electrical stimulation (TCES) offers a noninvasive approach to modulate the autonomic nervous system (ANS), but optimal stimulation parameters remain undefined. This pilot study aimed t...
Vagus nerve control of HMGB1 accessibility: a bioelectronic strategy for inflammation and pain [0.03%]
迷走神经对HMGB1的调控作用：针对炎症和疼痛的生物电子策略
Huan Yang,Michael Brines,Ulf Andersson
Huan Yang
High mobility group box 1 protein (HMGB1) is a central mediator of inflammation and pain, but efforts to neutralize it therapeutically have had limited clinical success. This gap suggests that the essential problem is not simply the abundan...
Effects of transcutaneous auricular vagus nerve stimulation or combined vagal and trigeminal nerve stimulation on platelet function and laboratory hemostasis parameters in healthy human subjects [0.03%]
耳迷走神经贴片刺激或联合面Vagus和三叉神经贴片刺激对健康人体血小板功能及实验室止血参数的影响
Jared M Huston,Carlos E Bravo-Iñiguez,Julien Papoin et al.
Jared M Huston et al.
Background: Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lympho...
A novel, wearable, in-ear EEG technology to assess sleep and daytime sleepiness [0.03%]
一种新型的可穿戴耳内EEG技术，用于评估睡眠和日间嗜睡症状
Jonathan Berent,Prabhjyot Saini,Andrew X Stewart et al.
Jonathan Berent et al.
In-ear electroencephalography (EEG) has emerged as a promising alternative to traditional in-laboratory sleep studies, offering greater comfort and practicality. Here we present a novel in-ear EEG system, comparing in-ear recordings against...
Participant-centered tolerability of transcutaneous auricular vagus nerve stimulation: insights from two crossover studies [0.03%]
经皮耳迷走神经刺激的以参与者为中心的耐受性：两项交叉研究的新见解
Gabriel Gonzalez,Maximillian O&#x;Malley,Jessica Bolanos et al.
Gabriel Gonzalez et al.
Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising noninvasive technique for modulating parasympathetic activity, yet optimal stimulation parameters and comprehensive tolerability profiles...
Vagus nerve stimulation in Crohn's disease: long-term outcomes, mechanistic insights, and the promise of non-invasive approaches [0.03%]
迷走神经刺激在克罗恩病中的长期疗效、机制见解及非侵入性方法的前景
Valérie Sinniger,Sonia Pellissier,Bruno Bonaz
Valérie Sinniger
Background: The vagus nerve (VN) has anti-inflammatory properties. We have previously reported in a 1-year pilot study that VN stimulation (VNS) improved patients with active Crohn’s disease (CD). In this paper, we prese...
A novel transcutaneous auricular neurostimulation electrode configuration for treatment of heavy menstrual bleeding: an open-label trial [0.03%]
一种新颖的经皮耳神经电刺激电极配置用于治疗月经过多：一项开放标记试验
Christopher J Czura,Angela C Weyand,Maureen K Baldwin et al.
Christopher J Czura et al.
Background: Electrical stimulation of the cervical vagus nerve reduces traumatic blood loss in models of soft tissue injury. This pathway, termed the neural tourniquet, can be accessed with a transcutaneous auricular neur...
Dimitrios A Koutsouras,Geert Langereis
Dimitrios A Koutsouras
Bioelectronic medicine (BEM) is an emerging scientific field that aims to revolutionize the way we understand and treat disease by using electrical impulses for diagnosis and therapy. It is an interdisciplinary endeavour that draws on advan...
Virtual reality volumetric rendering versus cross-sectional imaging for pancreatic cancer resectability assessment: a pilot randomized controlled reader study [0.03%]
针对胰腺癌切除可能性评估的虚拟现实体积渲染与横断面影像的读者随机对照试验：一项试点研究
Karl Eisenträger,Kaya Saribeyoglu,Uli Fehrenbach et al.
Karl Eisenträger et al.
Background: Current imaging assessment for pancreatic cancer resectability demonstrates problematic inter-observer variability, with only fair-to-moderate agreement among experienced raters. Virtual reality technology off...