Review of the role of the nervous system in glucose homoeostasis and future perspectives towards the management of diabetes [0.03%]
神经系统的功能在血糖同化以及未来糖尿病治疗的展望综述
Amparo Güemes,Pantelis Georgiou
Amparo Güemes
Diabetes is a disease caused by a breakdown in the glucose metabolic process resulting in abnormal blood glucose fluctuations. Traditionally, control has involved external insulin injection in response to elevated blood glucose to substitut...
Realizing flexible bioelectronic medicines for accessing the peripheral nerves - technology considerations [0.03%]
实现用于访问外周神经的柔性生物电子药物的技术考虑因素
Vasiliki Giagka,Wouter A Serdijn
Vasiliki Giagka
Patients suffering from conditions such as paralysis, diabetes or rheumatoid arthritis could in the future be treated in a personalised manner using bioelectronic medicines (BEms) (Nat Rev Drug Discov 13:399-400, 2013, Proc Natl Acad Sci US...
Electrical stimulation of renal nerves for modulating urine glucose excretion in rats [0.03%]
电刺激调控大鼠肾脏神经对尿糖排泄的影响
Ahmad A Jiman,Kavaljit H Chhabra,Alfor G Lewis et al.
Ahmad A Jiman et al.
Background: The role of the kidney in glucose homeostasis has gained global interest. Kidneys are innervated by renal nerves, and renal denervation animal models have shown improved glucose regulation. We hypothesized tha...
Recent advances in materials and flexible electronics for peripheral nerve interfaces [0.03%]
用于周围神经接口的材料和柔性电子器件的新进展
Christopher J Bettinger
Christopher J Bettinger
Peripheral nerve interfaces are a central technology in advancing bioelectronic medicines because these medical devices can record and modulate the activity of nerves that innervate visceral organs. Peripheral nerve interfaces that use elec...
B fibers are the best predictors of cardiac activity during Vagus nerve stimulation: Qing, vagal B fiber activation and cardiac effects [0.03%]
迷走神经中的B纤维是刺激时引起心脏效应的最主要原因-吕博士等人的研究发现
Kurt Y Qing,Kelsey M Wasilczuk,Matthew P Ward et al.
Kurt Y Qing et al.
Background: Vagus nerve stimulation (VNS) is a promising therapy for many neurologic and psychiatric conditions. However, determining stimulus parameters for individual patients is a major challenge. The traditional metho...
Is-there a place for vagus nerve stimulation in inflammatory bowel diseases? [0.03%]
迷走神经刺激在炎症性肠病中的作用不容小觑？
Bruno Bonaz
Bruno Bonaz
The vagus nerve (VN), the longest nerve of the organism that innervates the gastrointestinal tract, is a mixed nerve composed of 80% of afferent and 20% of efferent fibers. The VN has anti-inflammatory properties, in particular an anti-TNF...
Harold A Silverman,Andrew Stiegler,Téa Tsaava et al.
Harold A Silverman et al.
Background: The vagus nerve plays an important role in the regulation of organ function, including reflex pathways that regulate immunity and inflammation. Recent studies using genetically modified mice have improved our ...
Electroencephalographic read-outs of the modulation of cortical network activity by deep brain stimulation [0.03%]
深脑刺激对皮层网络活动调节的脑电图观测
Astrid Kibleur,Olivier David
Astrid Kibleur
Deep brain stimulation (DBS), a reversible and adjustable treatment for neurological and psychiatric refractory disorders, consists in delivering electrical currents to neuronal populations located in subcortical structures. The targets of ...
Paola Sanjuan-Alberte,Morgan R Alexander,Richard J M Hague et al.
Paola Sanjuan-Alberte et al.
Cellular homeostasis is in part controlled by biological generated electrical activity. By interfacing biology with electronic devices this electrical activity can be modulated to actuate cellular behaviour. There are current limitations in...
Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action [0.03%]
慢性疼痛的脊髓刺激疗法：作用机制的证据和理论
Jacob Caylor,Rajiv Reddy,Sopyda Yin et al.
Jacob Caylor et al.
Well-established in the field of bioelectronic medicine, Spinal Cord Stimulation (SCS) offers an implantable, non-pharmacologic treatment for patients with intractable chronic pain conditions. Chronic pain is a widely heterogenous syndrome ...