A pilot randomized controlled trial of supervised, at-home, self-administered transcutaneous auricular vagus nerve stimulation (taVNS) to manage long COVID symptoms [0.03%]
一项针对长新冠症状管理的耳皮层迷走神经刺激（taVNS）监督式家庭自给自足试点随机对照试验
Bashar W Badran,Sarah M Huffman,Morgan Dancy et al.
Bashar W Badran et al.
Background: Although the coronavirus disease 19 (COVID-19) pandemic has now impacted the world for over two years, the persistent secondary neuropsychiatric effects are still not fully understood. These "long COVID" sympt...
Delivering transcutaneous auricular neurostimulation (tAN) to improve symptoms associated with opioid withdrawal: results from a prospective clinical trial [0.03%]
经皮耳神经刺激(tAN)改善阿片类药物脱毒症状的临床研究
Carlos F Tirado,Stephanie N Washburn,Alejandro Covalin et al.
Carlos F Tirado et al.
Background: As pharmacological treatments are the primary option for opioid use disorder, neuromodulation has recently demonstrated efficacy in managing opioid withdrawal syndrome (OWS). This study investigated the safety...
Effects of waveform shape and electrode material on KiloHertz frequency alternating current block of mammalian peripheral nerve [0.03%]
载频为千赫兹的交流电阻断哺乳动物外周神经脉冲活动的效应及其影响因素研究
David B Green,Joseph A Kilgore,Shane A Bender et al.
David B Green et al.
Objectives: KiloHertz frequency alternating current waveforms produce conduction block in peripheral nerves. It is not clearly known how the waveform shape affects block outcomes, and if waveform effects are frequency dep...
Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival [0.03%]
经窒息性心脏骤停后调整阈值的迷走神经刺激可产生神经保护作用并提高生存率
Rishabh C Choudhary,Umair Ahmed,Muhammad Shoaib et al.
Rishabh C Choudhary et al.
Background: Vagus nerve stimulation (VNS) has shown therapeutic potential in a variety of different diseases with many ongoing clinical trials. The role of VNS in reducing ischemic injury in the brain requires further eva...
Umair Ahmed,Yao-Chuan Chang,Stefanos Zafeiropoulos et al.
Umair Ahmed et al.
The vagus nerve is involved in the autonomic regulation of physiological homeostasis, through vast innervation of cervical, thoracic and abdominal visceral organs. Stimulation of the vagus with bioelectronic devices represents a therapeutic...
Sex-specific differences in the efficacy of traditional low frequency versus high frequency spinal cord stimulation for chronic pain [0.03%]
传统低频和高频脊髓刺激的性别差异疗效研究慢性疼痛患者中
Rosalynn R Z Conic,Jacob Caylor,Christina L Cui et al.
Rosalynn R Z Conic et al.
Introduction: Spinal cord stimulation (SCS), an FDA-approved therapy for chronic pain, uses paresthesia (low frequency SCS (LF-SCS)) or paresthesia-free (such as high-frequency SCS (HF-SCS)) systems, providing analgesia t...
Theo Crosson,Sebastien Talbot
Theo Crosson
Background: Dorsal Root Ganglia (DRG) neurons are derived from the neural crest and mainly innervate the skin, while Jugular Nodose Complex (JNC) neurons originate from the placode and innervate internal organs. These gan...
Carl Erb,Sophie Eckert,Pia Gindorf et al.
Carl Erb et al.
Background: The retrospective study provides real-world evidence for long-term clinical efficacy of electrical optic nerve stimulation (ONS) in glaucoma with progressive vision loss. ...
Noninvasive spinal neuromodulation mitigates symptoms of idiopathic overactive bladder [0.03%]
无创脊髓神经调控可改善原发性过度活动膀胱的症状
Hui Zhong,Emilie Liu,Priya Kohli et al.
Hui Zhong et al.
Background: Overactive bladder (OAB) affects 12 to 30% of the world's population. The accompanying urinary urgency, frequency and incontinence can have a profound effect on quality of life, leading to depression, social i...
The impact of closed-loop intracortical stimulation on neural activity in brain-injured, anesthetized animals [0.03%]
闭环皮层电刺激对麻醉脑损伤动物神经元活动的影响
Marta Carè,Alberto Averna,Federico Barban et al.
Marta Carè et al.
Background: Acquired brain injuries, such as stroke, are a major cause of long-term disability worldwide. Intracortical microstimulation (ICMS) can be used successfully to assist in guiding appropriate connections to rest...