Vagus nerve control of HMGB1 accessibility: a bioelectronic strategy for inflammation and pain [0.03%]
迷走神经对HMGB1的调控作用：针对炎症和疼痛的生物电子策略
Huan Yang,Michael Brines,Ulf Andersson
Huan Yang
High mobility group box 1 protein (HMGB1) is a central mediator of inflammation and pain, but efforts to neutralize it therapeutically have had limited clinical success. This gap suggests that the essential problem is not simply the abundan...
Effects of transcutaneous auricular vagus nerve stimulation or combined vagal and trigeminal nerve stimulation on platelet function and laboratory hemostasis parameters in healthy human subjects [0.03%]
耳迷走神经贴片刺激或联合面Vagus和三叉神经贴片刺激对健康人体血小板功能及实验室止血参数的影响
Jared M Huston,Carlos E Bravo-Iñiguez,Julien Papoin et al.
Jared M Huston et al.
Background: Traumatic or surgical hemorrhage causes substantial morbidity and mortality. Electrical vagus nerve stimulation (VNS) reduces traumatic hemorrhage in animal models. VNS targets acetylcholine-producing T lympho...
A novel, wearable, in-ear EEG technology to assess sleep and daytime sleepiness [0.03%]
一种新型的可穿戴耳内EEG技术，用于评估睡眠和日间嗜睡症状
Jonathan Berent,Prabhjyot Saini,Andrew X Stewart et al.
Jonathan Berent et al.
In-ear electroencephalography (EEG) has emerged as a promising alternative to traditional in-laboratory sleep studies, offering greater comfort and practicality. Here we present a novel in-ear EEG system, comparing in-ear recordings against...
Participant-centered tolerability of transcutaneous auricular vagus nerve stimulation: insights from two crossover studies [0.03%]
经皮耳迷走神经刺激的以参与者为中心的耐受性：两项交叉研究的新见解
Gabriel Gonzalez,Maximillian O&#x;Malley,Jessica Bolanos et al.
Gabriel Gonzalez et al.
Background: Transcutaneous auricular vagus nerve stimulation (taVNS) is a promising noninvasive technique for modulating parasympathetic activity, yet optimal stimulation parameters and comprehensive tolerability profiles...
Vagus nerve stimulation in Crohn's disease: long-term outcomes, mechanistic insights, and the promise of non-invasive approaches [0.03%]
迷走神经刺激在克罗恩病中的长期疗效、机制见解及非侵入性方法的前景
Valérie Sinniger,Sonia Pellissier,Bruno Bonaz
Valérie Sinniger
Background: The vagus nerve (VN) has anti-inflammatory properties. We have previously reported in a 1-year pilot study that VN stimulation (VNS) improved patients with active Crohn’s disease (CD). In this paper, we prese...
A novel transcutaneous auricular neurostimulation electrode configuration for treatment of heavy menstrual bleeding: an open-label trial [0.03%]
一种新颖的经皮耳神经电刺激电极配置用于治疗月经过多：一项开放标记试验
Christopher J Czura,Angela C Weyand,Maureen K Baldwin et al.
Christopher J Czura et al.
Background: Electrical stimulation of the cervical vagus nerve reduces traumatic blood loss in models of soft tissue injury. This pathway, termed the neural tourniquet, can be accessed with a transcutaneous auricular neur...
Dimitrios A Koutsouras,Geert Langereis
Dimitrios A Koutsouras
Bioelectronic medicine (BEM) is an emerging scientific field that aims to revolutionize the way we understand and treat disease by using electrical impulses for diagnosis and therapy. It is an interdisciplinary endeavour that draws on advan...
Virtual reality volumetric rendering versus cross-sectional imaging for pancreatic cancer resectability assessment: a pilot randomized controlled reader study [0.03%]
针对胰腺癌切除可能性评估的虚拟现实体积渲染与横断面影像的读者随机对照试验：一项试点研究
Karl Eisenträger,Kaya Saribeyoglu,Uli Fehrenbach et al.
Karl Eisenträger et al.
Background: Current imaging assessment for pancreatic cancer resectability demonstrates problematic inter-observer variability, with only fair-to-moderate agreement among experienced raters. Virtual reality technology off...
A robust, real‑time telemetry protocol for miniaturized neural implants using off‑the‑shelf hardware [0.03%]
一种使用现成硬件的微型神经植入体的强大实时遥测协议
Mohamed Elgohary,Michael Recine,Jason Wong et al.
Mohamed Elgohary et al.
Background: Wireless telemetry from fully implanted, millimeter-scale neuromodulation devices is constrained by tight power budgets, inefficient antennas, and in-body attenuation. Standard protocols (e.g., BLE) offer matu...
Scaling beyond the vagus nerve: historical and contemporary progress on electrode-based small-diameter peripheral nerve interfaces [0.03%]
迷走神经之外的扩展：基于电极的小直径外周神经接口的历史与当代进展
Max Li,Christine Ly,Jinghua Wen et al.
Max Li et al.
Peripheral nerve interfaces play a central role in bioelectronic medicine. Since the early foundational experiments of Luigi Galvani in the 1770s, there have been over 250 years of development in electrical neuromodulation. Even so, current...