Genetic Risk Variants for Multiple Sclerosis and Other Loci Linked to Intrathecal Immunoglobulin G Synthesis [0.03%]
多发性硬化症的遗传风险变异和其他与脑脊液免疫球蛋白G合成相关的位点
Albert Pukaj,Adil Harroud,Klementy Shchetynsky et al.
Albert Pukaj et al.
Background and objectives: Intrathecal synthesis of immunoglobulin G (IgG) is a key feature of multiple sclerosis (MS) and a prognostic marker for the disease course. Although previous studies identified 2 genetic regions...
Clinical Spectrum, Pathology, and Mechanisms of Anti-LGI4 Antibody-Positive Autoimmune Nodopathy [0.03%]
抗LGI4抗体阳性自身免疫性节结病的临床谱系、病理和机制
Xu Zhang,Jun-Ichi Kira,Akira Yokote et al.
Xu Zhang et al.
Background and objectives: The aim of this study was to elucidate the clinical spectrum and mechanisms of autoimmune nodopathy (AN) with autoantibodies against leucine-rich repeat leucin-rich glioma inactivated 1 (LGI) fa...
Extracellular Vesicles as Novel Biomarkers for Tumor Association in Intermediate-Risk Paraneoplastic Neurologic Syndromes [0.03%]
中间风险伴癌神经综合征肿瘤相关的新生物标志物外泌体
Gabriel Torres Iglesias,Alba Chavarría-Miranda,MariPaz López-Molina et al.
Gabriel Torres Iglesias et al.
Background and objectives: Paraneoplastic neurologic syndromes (PNS) are cancer-related neurologic disorders caused by an autoimmune response targeting both the tumor and the nervous system. Identifying new biomarkers for...
Temporal Association Between Dengue Outbreaks and Neurologic Autoimmune Diseases in French Guiana [0.03%]
法属圭亚那登革热流行与神经免疫疾病发病时间关联性分析
Nathalie Deschamps,Mathieu Nacher,Hugo Chaumont et al.
Nathalie Deschamps et al.
Background and objectives: Recent decades have witnessed the emergence of arbovirus infections, such as dengue, chikungunya, and Zika viruses, which are responsible for neurologic complications such as Guillain-Barré syn...
Iatrogenic Cerebral Amyloid Angiopathy-Related Inflammation: A Multicenter Case Series [0.03%]
医源性脑淀粉样血管炎相关炎症：多中心病例系列
Benedetta Storti,Giulia Negro,Giorgia Orsani et al.
Benedetta Storti et al.
Background and objectives: Variants of cerebral amyloid angiopathy (CAA) have been increasingly reported. Iatrogenic CAA (iCAA) is a subtype arising in patients with a history of neurosurgery. Current etiopathogenetic hyp...
Hiding in Plain Sight: Inflammation in Iatrogenic Cerebral Amyloid Angiopathy [0.03%]
显而易见的隐藏：医源性脑淀粉样血管病中的炎症作用
Gargi Banerjee,David John Werring
Gargi Banerjee
Acute Hemorrhagic Leukoencephalitis With Active Hepatitis B Virus Infection: A Case Report [0.03%]
活动性乙型肝炎病毒感染并发急性出血性脑白质炎一例报告
Shivam Mirg,Jasmine Parihar,Manjari Tripathi et al.
Shivam Mirg et al.
CNS involvement in hepatitis B virus (HBV) infection is rare. We report a 27-year-old woman with HBV infection presenting with headaches and seizures, whose imaging and brain biopsy confirmed acute hemorrhagic leukoencephalitis. She respond...
Serum Neurofilament Light Chain Correlates With Clinical Severity and Predicts Mortality in Anti-IgLON5 Disease [0.03%]
抗IgLON5病患者血清神经丝轻链与临床严重程度相关，并可预测死亡风险
Antonio Farina,Macarena Villagrán-García,Amna Abichou-Klich et al.
Antonio Farina et al.
Background and objectives: Anti-IgLON5 disease manifests by various neurologic symptoms, the severity of which can be evaluated using the anti-IgLON5 composite score (ICS). This study assessed the correlation of neurofila...
CSF Beta-Synuclein, SNAP-25, and Neurogranin in Infectious and Autoimmune Inflammatory Neurologic Diseases [0.03%]
感染性和自身免疫性炎症神经病的脑脊液β-突触核蛋白、SNAP-25和星 dacinин
Samir Abu-Rumeileh,Deborah K Erhart,Lorenzo Barba et al.
Samir Abu-Rumeileh et al.
Background and objectives: Beta-synuclein (beta-syn), synaptosomal-associated protein 25 (SNAP-25), and neurogranin are CSF biomarkers of synaptic damage, which have been poorly investigated in non-neurodegenerative neuro...
Applying the Supporting Features for MOGAD Diagnosis to Patients With Multiple Sclerosis [0.03%]
将MOGAD诊断的辅助特征应用于多发性硬化患者中
Pietro Zara,Giacomo Greco,Francesco Masi et al.
Pietro Zara et al.
Background and objectives: In the 2023 diagnostic criteria, supporting clinical/MRI features are required to diagnose myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) in patients at high risk of fal...