Johanna Oechtering,Sabine Anna Schaedelin,Aleksandra Maleska Maceski et al.
Johanna Oechtering et al.
Background and objectives: Accurate biomarkers that reflect disease activity, severity, and molecular pathophysiology in multiple sclerosis (MS) remain an unmet diagnostic need. We compared the performance of the establis...
Jackson W Mace,Matthew D Smith,Sachin P Gadani et al.
Jackson W Mace et al.
Background and objectives: Multiple sclerosis (MS) is characterized by peripheral immune cell infiltration into the central nervous system (CNS) and associated reactive gliosis, demyelination, and neuroaxonal degeneration...
Shared Epitope-Positive HLA Alleles Protect Against Alpha-Synuclein Pathology in a Model of Parkinson Disease [0.03%]
Jonathan J Carver,Bryce A Pugh,Qin Ma et al.
Jonathan J Carver et al.
Background and objective: There is increasing evidence that human leukocyte antigen (HLA) allelic variants play a role in the genetic predisposition to Parkinson disease (PD). In this regard, we have recently reported tha...
Comparative Effectiveness of Disease-Modifying Treatments in Double Seronegative Neuromyelitis Optica Spectrum Disorder [0.03%]
Joao Vitor Mahler,Gerome B Vallejos,Takahisa Mikami et al.
Joao Vitor Mahler et al.
Dynamics of Spinal Fluid Immune Cell Alterations Following Cladribine Tablet Treatment in Multiple Sclerosis [0.03%]
Roman A Smirnov,Claudia Cantoni,Kenneth Lee et al.
Roman A Smirnov et al.
Background and objectives: Oral cladribine tablet (CladT) therapy is efficacious for relapsing multiple sclerosis (MS). However, the mechanisms by which cladribine exerts benefit in MS remain unclear, particularly regardi...
HLA Associations Differ by Ethnicity and Aquaporin-4 Antibody Status in Patients With Neuromyelitis Optica Spectrum Disorders [0.03%]
Moritz Niederschweiberer,Georgia Panagiotaropoulou,Marcelo A Fernandez-Viña et al.
Moritz Niederschweiberer et al.
Background and objectives: Neuromyelitis optica spectrum disorders (NMOSDs) comprise inflammatory processes of the CNS. Most patients with NMOSD have serum immunoglobulin (Ig) G autoantibodies directed against the astrocy...
Real-World Efficacy and Safety of Neuromyelitis Optica Spectrum Disorder Disease-Modifying Treatments [0.03%]
视神经脊髓炎谱系病疾病修正治疗的现实世界有效性和安全性
Philippe A Bilodeau,Mattia Wruble Clark,Avanteeka Ganguly et al.
Philippe A Bilodeau et al.
Vestibular and Ocular Motor Phenotype in a Case of Paraneoplastic Autoimmune Kelch-Like Protein-11 Encephalitis [0.03%]
视神经脊髓炎相关抗肾小管基底膜蛋白抗体视 vestibular和眼肌麻痹特征性病例报告
Felix Konstantin Schwarz,Romana Höftberger,Verena Endmayr et al.
Felix Konstantin Schwarz et al.
Objectives: KLHL11 encephalitis is often associated with vestibular symptoms and ataxia. However, the specific disorders of the vestibular and oculomotor systems have only been partially investigated so far. We present a ...
TRUE-MOGAD Score: A Novel Scoring System to Identify MOGAD Among Positive MOG-IgG Test Results [0.03%]
真正的MOGAD评分系统：一种识别阳性MOG-IgG检测结果中MOGAD的新型评分系统
Andreu Vilaseca,Angeliki G Filippatou,Yana Said et al.
Andreu Vilaseca et al.
Objectives: Myelin oligodendrocyte glycoprotein (MOG) antibodies (MOG-IgG) are a biomarker of MOG antibody-associated disease (MOGAD). However, false positives remain common. We aimed to develop a scoring tool to guide in...
Rapidly Progressive and Relapsing Myelitis With Human T Lymphotropic Virus Type 1: A Case Report and Review of the Literature [0.03%]
与人T淋巴细胞病毒I型相关急性进行性及复发性脊髓炎一例报告及文献复习
Andrew A Morrison,Rohini D Samudralwar,Joseph R Berger
Andrew A Morrison
A patient presented to our center in the northeastern United States with recurrent longitudinally extensive myelitis which was ultimately attributed to infection with human T lymphotropic virus type 1 (HTLV-1). The most common neurologic pr...