Myalgia with the presence of pathologic EMG correlates with perimysial inflammatory infiltrates [0.03%]
肌电图病理改变伴肌痛与小血管周围炎症细胞浸润相关
Kirsten Johannssen,Nicholas Schwab,Carsten P Wessig et al.
Kirsten Johannssen et al.
Objective: We aimed to define normal numbers of inflammatory cells in muscle biopsies and to identify the predictive value of isolated muscle pain and increased creatine kinase regarding the diagnosis of myositis. ...
CSF Proteins Associated With Neuroaxonal Damage in Early Active Multiple Sclerosis [0.03%]
早期活跃型多发性硬化症中与神经轴突损伤相关的脑脊液蛋白
Felix Luessi,Chiara Starvaggi Cucuzza,Sinah Engel et al.
Felix Luessi et al.
Background and objectives: The aim of this study was to identify biological processes associated with neuroaxonal degeneration in multiple sclerosis (MS) by analyzing protein patterns linked to neurofilament light (NfL) p...
Ganglion Cell Layer Compared With Inner Plexiform Layer Atrophy After Optic Neuritis Associated With NMOSD, MOGAD, and MS [0.03%]
NMOSD、MOGAD和多发性硬化症相关视神经炎后视网膜 ganglion cell layer 和 inner plexiform layer 萎缩的比较
Angeliki G Filippatou,Georgios Gakis,Anna Bacchetti et al.
Angeliki G Filippatou et al.
Background and objectives: Optic neuritis (ON) is a common manifestation of multiple sclerosis (MS), aquaporin-4-IgG seropositive neuromyelitis optica spectrum disorder (AQP4+NMOSD), and myelin oligodendrocyte glycoprotei...
Cytomegalovirus Drives the Development of Cytotoxic CD4+ T Cells in Patients With Multiple Sclerosis [0.03%]
巨细胞病毒驱动多发性硬化症患者 cytotoxic CD4+t 细胞的发展
Cindy Hoeks,Bram Boeckx,Paulien Baeten et al.
Cindy Hoeks et al.
Background and objectives: Chronic immune activation is a hallmark of latent viral infections and autoimmune disorders, profoundly shaping immune cell phenotypes, including CD4+ cytotoxic T lymphocytes (CD4 CTL). The mech...
Development of a Diagnostic Autoantibody Assay to a Consensus Motif for the Risk Prediction of Epstein-Barr Virus-Related Multiple Sclerosis [0.03%]
开发针对Epstein-Barr病毒相关多发性硬化症风险预测的诊断自身抗体检测方法以达成共识动机
Krista M McCutcheon,Aaron Bodansky,Thomas T Ngo et al.
Krista M McCutcheon et al.
Background and objectives: Multiple sclerosis (MS) is a chronic progressive, demyelinating autoimmune CNS disease. Autoantibodies to the motif P-(SA)-x-(SGA)-R-(SN)-(LRKH) are a class of predictive markers specific to MS ...
Fulminant Amyloid β-Related Angiitis With Herniation and Rapid Response to Tocilizumab: A Case Report [0.03%]
由托珠单抗治疗的急性Aβ相关性血管炎并发脑疝及快速反应1例报告
James V Nguyen,Emma M Byrne,Salina Yuan et al.
James V Nguyen et al.
Objectives: Amyloid β-related angiitis (ABRA) is a rare, inflammatory vasculopathy resulting from intravascular amyloid deposition. We describe a refractory presentation of ABRA and its response to tocilizumab. ...
Interleukin-9 Regulates NF-kB-Mediated Activation of Astrocytes in Multiple Sclerosis Brain [0.03%]
白细胞介素9调节NF-κB介导的小胶质细胞活化在多发性硬化脑中的作用
Miriam Cinotti,Susanna Amadio,Daniele Tidei et al.
Miriam Cinotti et al.
Abdu Kisekka Musubire,Judith Derdelinckx,Tatjana Reynders et al.
Abdu Kisekka Musubire et al.
Low Prevalence and Inconsistency of LRP4-IgG Detection in Suspected Myasthenia Gravis: A Multicenter CBA Comparison [0.03%]
LRP4-IgG在疑似重症肌无力患者中低阳性率及检测不一致的多中心流式荧光免疫分析法对比研究
Ilaria Gligora,Pietro Businaro,Lucrezia Serra et al.
Ilaria Gligora et al.
Background and objectives: Myasthenia gravis (MG) is an autoimmune disorder primarily caused by antibodies targeting neuromuscular junction proteins, particularly the acetylcholine receptor and the muscle-specific tyrosin...
Outcome Predictors in Progressive Multifocal Leukoencephalopathy Associated With Multiple Sclerosis Treatments: A Multicenter Cohort Study [0.03%]
与多发性硬化症治疗相关的进行性多灶性白质脑病的预后预测因素：一项基于多个中心队列的研究
Julie Céline Blant,Nicola De Rossi,Ralf Gold et al.
Julie Céline Blant et al.
Background and objectives: JC virus (JCV) reactivation causing progressive multifocal leukoencephalopathy (PML) is a complication in patients with multiple sclerosis (MS) treated with disease-modifying therapies (DMTs). A...