Angiogenesis and Hypoxia Biomarkers Are Dysregulated in Progressive Multiple Sclerosis [0.03%]
进行性多发性硬化病患者中血管生成和缺氧的生物标志物异常
Heather Y F Yong,Rajiv W Jain,Maria Goiko et al.
Heather Y F Yong et al.
Background and objectives: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative CNS disorder characterized by a state of "virtual hypoxia." Angiogenesis, one of the main homeostatic responses to hypoxia, h...
Persons With Multiple Sclerosis Reveal Distinct Kynurenine Pathway Metabolite Patterns: A Multinational Cross-Sectional Study [0.03%]
多发性硬化患者显示出不同的犬尿氨酸代谢模式：一项跨国横断面研究
Marie Kupjetz,Martin Langeskov-Christensen,Morten Riemenschneider et al.
Marie Kupjetz et al.
Background and objectives: Kynurenine pathway (KP) metabolites modulate inflammatory activity and neuronal viability. The consequences of KP imbalance partly resemble the molecular mechanisms of multiple sclerosis (MS). A...
Correlation of C-Reactive Protein With Severe Fatigue in Patients With Myasthenia Gravis [0.03%]
C-反应蛋白与重症肌无力患者严重疲劳的相关性研究
Annabel M Ruiter,Krista E van Meijgaarden,Simone A Joosten et al.
Annabel M Ruiter et al.
Background and objectives: Most patients with myasthenia gravis (MG) suffer from fatigue, which can be defined as a subjective lack of energy and difficulty in initiating or sustaining voluntary activities. This is concep...
Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor Antibodies: Clinical Features and Outcomes [0.03%]
具有氯化物通道抗体的进行性脑炎肌病 rigid 和 myoclonus 临床特征和转归分析
Mar Guasp,Albert Saiz,Marina Ruiz-Vives et al.
Mar Guasp et al.
Background and objectives: The aim of this study was to describe the clinical features and long-term outcome of patients with glycine receptor (GlyR) antibody-mediated progressive encephalomyelitis with rigidity and myocl...
Epstein-Barr Virus in Multiple Sclerosis: Past, Present, and Future [0.03%]
Epstein-Barr病毒与多发性硬化症：过去、现在和未来
Farah Wahbeh,Joseph J Sabatino
Farah Wahbeh
Epstein-Barr virus (EBV) is a very common herpesvirus that infects more than 90% of the general population. Epidemiologic data indicate that EBV is a requisite risk factor for the development of multiple sclerosis (MS); however, the mechani...
Risk of Epilepsy and Factors Associated With Time to Seizure Remission in Anti-LGI1 Encephalitis: Long-Term Outcome in 236 Patients [0.03%]
抗LGI1脑炎癫痫风险及影响无发作时间因素：236例患者的长期预后研究
Tobias Baumgartner,Moritz Freyberg,Lucia Campetella et al.
Tobias Baumgartner et al.
Background and objectives: Autoimmune encephalitis (AIE) with anti-leucine-rich glioma-inactivated 1 (LGI1) antibodies typically manifests with subacute cognitive deficits, seizures, and psychiatric symptoms, mostly in ol...
IV Immunoglobulin Is Associated With Epigenetic, Ribosomal, and Immune Changes in Pediatric Acute-Onset Neuropsychiatric Syndrome [0.03%]
儿童急性起病神经精神综合征中免疫球蛋白与表观遗传、核糖体和免疫改变相关性研究
Velda X Han,Hiroya Nishida,Brooke A Keating et al.
Velda X Han et al.
Objectives: Pediatric acute-onset neuropsychiatric syndrome (PANS) is characterized by infection-provoked abrupt-onset obsessive compulsive disorder (OCD) and neurodevelopmental regression. Owing to the neuroimmune hypoth...
Complement Factor I Deficiency With Acute Hemorrhagic Leukoencephalitis and Longitudinally Extensive Transverse Myelitis: A Case Report [0.03%]
补体因子I缺乏并发急性出血性白质脑炎和长节段横贯性脊髓炎1例报告
Tiffany Hu,Javier Rodriguez,Lara L Zimmermann et al.
Tiffany Hu et al.
Objectives: Complement factor I (CFI) deficiency is a rare condition that can present with fulminant relapsing CNS autoinflammation. In this report, we highlight the utility of genetic testing in unexplained CNS autoinfla...
Incidence, Etiology, and Long-Term Outcome of Acute Myelitis in Stockholm County, Sweden: A Population-Based Study [0.03%]
瑞典斯德哥尔摩县急性髓性白血病的发病率、病因及长期结局：一项基于人口的研究
Dagur Ingi Jonsson,Olafur Sveinsson,Nina Moeini et al.
Dagur Ingi Jonsson et al.
Background and objectives: Myelitis is a relatively common clinical entity for neurologists, with diverse underlying causes. The aim of this study was to describe the incidence of myelitis, its causes, clinical presentati...
Relation of Visual Function, Retinal Thickness by Optical Coherence Tomography, and MRI Brain Volume in Pediatric-Onset Multiple Sclerosis [0.03%]
儿童期发病的多发性硬化患者视力、视网膜厚度及脑MRI体积的关系
Anna Sosa,Kimberly A O&#x;Neill,Ruben Jauregui et al.
Anna Sosa et al.
Background and objectives: While reductions in optical coherence tomography (OCT) pRNFL and ganglion cell-inner plexiform layer thicknesses have been shown to be associated with brain atrophy in adult-onset MS (AOMS) coho...