Advantages and Limitations in the Use of Combination Therapies with Charged Particle Radiation Therapy [0.03%]
带电粒子放射治疗联合疗法的优缺点分析
Koji Tsuboi
Koji Tsuboi
Purpose: Studies are currently underway to help provide basic and clinical evidence for combination particle beam radiation therapy, on which there are few published reports. The purpose of this article is to summarize th...
Younghyun Lee,Ryuichi Okayasu
Younghyun Lee
Heavy ion radiation therapy has been increasingly used due to several advantages over low linear energy transfer (LET) photon therapy, but further improvement of its therapeutic efficacy would be necessary. In this review, we summarize effe...
Combining Heavy-Ion Therapy with Immunotherapy: An Update on Recent Developments [0.03%]
离子治疗结合免疫治疗的最新研究进展
Alexander Helm,Daniel K Ebner,Walter Tinganelli et al.
Alexander Helm et al.
Clinical trials and case reports of cancer therapies combining radiation therapy with immunotherapy have at times demonstrated total reduction or elimination of metastatic disease. While virtually all trials focus on the use of immunotherap...
David R Grosshans,Joseph G Duman,M Waleed Gaber et al.
David R Grosshans et al.
For patients with primary or metastatic brain tumors, radiation therapy plays a central role in treatment. However, despite its efficacy, cranial radiation is associated with a range of side effects ranging from mild cognitive impairment to...
Molecular Signaling in Response to Charged Particle Exposures and its Importance in Particle Therapy [0.03%]
带电粒子辐射的分子信号转导及其在重离子治疗中的意义
Christine E Hellweg,Arif Ali Chishti,Sebastian Diegeler et al.
Christine E Hellweg et al.
Energetic, charged particles elicit an orchestrated DNA damage response (DDR) during their traversal through healthy tissues and tumors. Complex DNA damage formation, after exposure to high linear energy transfer (LET) charged particles, re...
Cancer Cell Metabolism: Implications for X-ray and Particle Radiation Therapy [0.03%]
癌症细胞代谢与放射和粒子放射治疗的相互作用
Mathieu Sertorio,John P Perentesis,Ralph E Vatner et al.
Mathieu Sertorio et al.
Advances in radiation delivery technologies and immunotherapy have improved effective cancer treatments and long-term outcomes. Experimental and clinical trials have demonstrated the benefit of a combination of radiation therapy and immunot...
Robert D Stewart
Robert D Stewart
The specific types and numbers of clusters of DNA lesions, including both DNA double-strand breaks (DSBs) and non-DSB clusters, are widely considered 1 of the most important initiating events underlying the relative biological effectiveness...
Comparing Photon and Charged Particle Therapy Using DNA Damage Biomarkers [0.03%]
基于DNA损伤生物标志物的光子与带电粒子放疗比较研究
Shayoni Ray,Egle Cekanaviciute,Ivan Paulino Lima et al.
Shayoni Ray et al.
Treatment modalities for cancer radiation therapy have become increasingly diversified given the growing number of facilities providing proton and carbon-ion therapy in addition to the more historically accepted photon therapy. An understan...
An Introduction to the International Journal of Particle Therapy's Special Issue on Charged Particle Radiobiology [0.03%]
国际粒子治疗杂志charged particle radiobiology专栏介绍
Marcelo E Vazquez
Marcelo E Vazquez