Patient-Specific Deep Reinforcement Learning for Proton Beam Delivery Under Inter-Phase Variations [0.03%]
考虑相间变化的 proton 放疗过程中的基于深度强化学习的患者个性化治疗优化方法研究
Mélanie Ghislain,Estelle Loÿen,Antoine Aspeel et al.
Mélanie Ghislain et al.
Purpose: Proton therapy is challenged by tumor motion, particularly for lung tumors affected by respiratory-induced motion. Conventional planning strategies compensate for this motion by introducing safety margins or by u...
Clinical Comparison of Beam-Specific Planning Target Volume Single-Field Uniform Dose and Robust Intensity-Modulated Proton Therapy in Ultra-Hypofractionation for Prostate Cancer [0.03%]
单次大剂量适形 proton治疗和稳健型调强proton治疗在超高分割治疗前列腺癌中的临床对比研究：等中心照射点计划靶区体积的分析
Hiroshi Tamura,Takaaki Yoshimura,Keiji Nakazato et al.
Hiroshi Tamura et al.
Purpose: This study aimed to compare the robustness of beam-specific planning target volume (bs-PTV)-based single-field uniform dose (SFUD) and robustly optimized intensity-modulated proton therapy (IMPT) plans against se...
Dosimetric Comparison Between Brass Aperture-Enhanced Proton Pencil Beam Scanning and Photon Stereotactic Radiosurgery for Cerebral Arteriovenous Malformations [0.03%]
用于脑动静脉畸形的 brass 垫圈增强质子笔形束扫描与光子立体定向放射外科治疗的剂量比较
Will Sperduto,Mattison J Flakus,Ed Clouser et al.
Will Sperduto et al.
Purpose: The current study aimed to quantify potential dosimetric advantages of a novel, brass aperture-enhanced, proton-based stereotactic radiosurgery (SRS) technique compared to conventional photon linac-based SRS in p...
Commissioning and Validation of a Synchrocyclotron - Based Ultra-High-Dose-Rate Beamline for FLASH [0.03%]
基于同步回旋加速器的超高剂量率辐照束线的安装与验收用于FLASH放射治疗研究
Yuting Lin,Jufri Setianegara,Aoxiang Wang et al.
Yuting Lin et al.
Purpose: FLASH radiotherapy delivers ultra-high dose rate radiation (>40 Gy/s) has shown promise in reducing normal tissue toxicity while maintaining tumor control. IBA's single-room proton system, equipped with S2C2 supe...
Evaluations of Penumbra Reduction Using Multi-Leaf Collimator and 3D Bolus in Scanned Proton Therapy [0.03%]
扫描 proton 治疗中多叶准直器和三维敷料的半影缩减评估
Yuki Tominaga,Robabeh Rahimi,Yushi Wakisaka et al.
Yuki Tominaga et al.
Purpose: Proton therapy offers excellent distal tissue sparing; however, precise control of the lateral penumbra is critical for protecting adjacent healthy tissues. This study systematically evaluated improvements in lat...
Miscia Fortna,Nancy P Mendenhall,Daniel Lichlyter et al.
Miscia Fortna et al.
Purpose: We present long-term outcomes of men young aged 50 years or younger treated for localized prostatic adenocarcinoma with image-guided proton therapy (PT). ...
Neural Representation Learning for Compact and Efficient Modeling of Monte Carlo Phase Space Data [0.03%]
紧凑而高效的蒙特卡罗相空间数据神经表征学习方法
Serdar Charyyev,Cynthia Chuang,Yong Yang et al.
Serdar Charyyev et al.
Purpose: Monte Carlo (MC) simulations provide gold standard dose calculations in radiation therapy but generate large phase space (PHSP) files that limit clinical implementation. We developed NeRP-MC, the first neural rep...
Validation of the Effectiveness of Visual Feedback Systems in Respiratory Gating Carbon Ion Radiation Therapy [0.03%]
验证视觉反馈系统在呼吸门控碳离子放射治疗中的有效性
Ren Umetani,Yuya Miyasaka,Hikaru Souda et al.
Ren Umetani et al.
Background: This study aimed to evaluate the efficacy of respiratory-gated irradiation using visual feedback (VF) in carbon-ion radiotherapy (CIRT). Furthermore, in patients with liver cancer undergoing CIRT, the treatmen...
Emerging Outcome Trends From Proton Therapy for Pediatric CNS Tumors: A Systematic Review [0.03%]
质子治疗儿童中枢神经系统肿瘤的系统评价：疗效趋势分析
Jasper Greenland,Jake Kendrick,Martin A Ebert et al.
Jasper Greenland et al.
Purpose: This systematic review aims to provide a summary of outcomes of pediatric brain tumor patients treated with proton therapy (PT). Outcomes focused on include long-term efficacy and late toxicities. This study prov...
Biologically Effective Dose-Optimized Multi-Intensity-Modulated Proton Therapy: A Biologically Comparable Alternative to Proton Arc Therapy [0.03%]
生物效应剂量优化的多强度调制质子治疗：弧形质子治疗的一种生物等效替代疗法
Nimita Shinde,Yanan Zhu,Wei Wang et al.
Nimita Shinde et al.
Purpose: Proton spot-scanning arc therapy (ARC) is an emerging technique that can enhance high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). Although proton ARC is highly des...