Chronic High Fat Diet Consumption Impairs Metabolic Health of Male Mice [0.03%]
高脂饮食通过改变肠道菌群引起代谢紊乱及肠道通透性增加导致慢性炎症和胰岛素抵抗
Eugenia Morselli,Alfredo Criollo,Carlos Rodriguez-Navas et al.
Eugenia Morselli et al.
We show that chronic high fat diet (HFD) feeding affects the hypothalamus of male but not female mice. In our study we demonstrate that palmitic acid and sphingolipids accumulate in the central nervous system of HFD-fed males. Additionally,...
Proteinase 3 and Serpin B1: a novel pathway in the regulation of caspase-3 activation, neutrophil spontaneous apoptosis, and inflammation [0.03%]
蛋白酶3和Serpine B1：在调控caspase-3激活，中性粒细胞自发凋亡及炎症中的新通路
Fabien Loison,Yuanfu Xu,Hongbo R Luo
Fabien Loison
Neutrophils are the first responders of the inflammatory response. They are characterized by their potent cytotoxic content but also by their limited lifetime. This short half-life is thought to be a self-protecting mechanism for the host, ...