Impact of race-based calculations of eGFR on the management of muscle invasive bladder cancer [0.03%]
基于种族的eGFR计算对肌层浸润性膀胱癌治疗的影响
Amir Khan,Shu Wang,Kathryn Hughes Barry et al.
Amir Khan et al.
Purpose: The estimated glomerular filtration rate (eGFR) has historically been calculated with a race-coefficient multiplier (RCM); however, the RCM has been broadly criticized as inaccurate and a potential contributor to...
Impact of cell plasticity on prostate tumor heterogeneity and therapeutic response [0.03%]
细胞多能性对前列腺肿瘤异质性和治疗反应的影响
Maddison Archer,Kevin M Lin,Kaushik P Kolanukuduru et al.
Maddison Archer et al.
Epithelial-mesenchymal transition (EMT) is a dynamic process of lineage plasticity in which epithelial cancer cells acquire mesenchymal traits, enabling them to metastasize to distant organs. This review explores the current understanding o...
SOX2 control activation of dormant prostate cancer cells in bone metastases by promoting CCNE2 gene expression [0.03%]
SOX2通过促进CCNE2基因表达激活骨转移性前列腺癌细胞
Min Deng,Pei-Zheng Huang,Ze-Yu Huang et al.
Min Deng et al.
Background: Cancer stem cells (CSCs) have a powerful tumor initiation ability, which can promote the early dissemination of single disseminated tumor cells (DTCs), leading to tumor progression. SOX2, a pluripotent inducib...
Non-Hodgkin's primary lymphoma involving the genitourinary tract: histopathological experience from two tertiary hospitals, Western region, Saudi Arabia [0.03%]
沙特阿拉伯西部地区两家三级医院涉及泌尿生殖道的非霍奇金原发性淋巴瘤的病理经验
Haneen Al-Maghrabi,Jaudah Al-Maghrabi
Haneen Al-Maghrabi
Background: Urinary tract and male genital organ lymphoid neoplasms are uncommon, accounting for less than 5% of all primary extranodal lymphomas. There have only been a few small case series and isolated case reports des...
Prioritizing precision: detection of prostate cancer using mri guided fusion needle biopsy across the pennsylvania urologic regional collaborative [0.03%]
精准检测：使用MRI引导的融合针活检在宾夕法尼亚泌尿区域协作中检测前列腺癌
Dennis Head,Ako A Ako,Serge Ginzburg et al.
Dennis Head et al.
Purpose: Targeted prostate biopsies are increasingly being performed by urologists in the United States including those in the Pennsylvania Urologic Regional Collaborative, a physician-led data-sharing and quality improve...
Decreased expression of LncRNA CRYM-AS1 promotes apoptosis through the Hippo-YAP1 signaling pathway leading to diabetic erectile dysfunction [0.03%]
LncRNA CRYM-AS1表达下调通过Hippo-YAP1信号通路促进糖尿病勃起功能障碍的凋亡发生
Ze-Bo Zhang,Ying Chen,Zhan-Sen Huang et al.
Ze-Bo Zhang et al.
Long non-coding RNAs (lncRNAs) primarily engage with mRNA, DNA, proteins, and microRNAs (miRNAs), thereby regulating gene expression; however, its specific role in diabetic erectile dysfunction (DED) has not been studied. This study aims to...
Administering antibiotic-loaded irrigation fluid as an alternative for prophylactic intravenous antibiotics in transurethral ureterolithotripsy (TUL): a randomized controlled trial [0.03%]
输尿管镜碎石术中应用抗生素灌注替代预防性静脉使用抗生素的随机对照试验
Seyed Mohammad Kazem Aghamir,Reza Mohammadi Farsani,Amirreza Shamshirgaran et al.
Seyed Mohammad Kazem Aghamir et al.
Prophylactic antibiotics are commonly used to prevent infections and complications during surgeries. In this study inflammatory responses and infectious complications after utilizing antibiotic-loaded irrigation compared with intravenous (I...
A Mendelian randomisation approach to explore genetic factors associated with erectile dysfunction based on pooled genomic data [0.03%]
基于组学整合数据的男性功能障碍遗传因素 mendel 随机化分析研究
Hai Mao,Jianjun Li,Feiqiang Ren et al.
Hai Mao et al.
Background: Genetic factors are thought to play a major role in erectile dysfunction (ED), but the search for specific ED-related genes remains a mysterious area characterised by limited and inconclusive research. ...
Minimally invasive management of extraperitoneal bladder injury with extension to the trigone of the bladder with bilateral external ureteral catheterization: innovative approach instead of open surgical treatment [0.03%]
经尿道输尿管导管置入治疗膀胱三角区及腹膜外膀胱破裂损伤的微创手术疗法及相关护理措施——创新性地避免开放性手术治疗方法
Reza Kazemi,Faezeh Sadat Jandaghi,Farzaneh Montazeri
Reza Kazemi
This case study emphasizes the critical role of accurate diagnosis and tailored management strategies in successfully treating bladder injuries, particularly in complex cases. We present a patient with trigonal involvement and a Grade V inj...
Ubiquitin C-terminal hydrolase L1 is a regulator of tumor growth and metastasis in double-negative prostate cancer [0.03%]
泛素羧基末端水解酶L1是双阴性前列腺癌肿瘤生长和转移的调节因子
Shiqin Liu,Fernando Jose Garcia-Marques,Michelle Shen et al.
Shiqin Liu et al.
Prostate cancer is the second leading cause of cancer-related deaths among men worldwide. With heavy androgen deprivation therapies, prostate cancer may shift to androgen receptor negative and neuroendocrine negative subtype of castration r...