Regenerative strategies for post-prostatectomy incontinence: stem cells, exosomes, and the path to clinical resolution [0.03%]
前列腺术后尿失禁的再生治疗策略:干细胞、外泌体及临床治愈之路
William Wang,Tarek Zaho,Allen Cao et al.
William Wang et al.
Radical prostatectomy (RP) is a highly effective treatment for localized prostate cancer; unfortunately, post-prostatectomy urinary incontinence (UI) remains a prevalent and distressing complication, significantly diminishing patients' qual...
Peripheral serotonin contributes to testosterone and estradiol induced urinary voiding dysfunction in adult male mice [0.03%]
外周血清素参与了雄性小鼠睾丸酮和雌二醇诱导的排尿功能障碍的作用
Jojo Maier,Elliot Heye,Monica Ridlon et al.
Jojo Maier et al.
Objective: Millions of aging men are diagnosed with lower urinary tract dysfunction (LUTD) each year. Alpha adrenergic receptor blockers relax prostatic, urethral, and bladder smooth muscle to relieve LUTD symptoms and ar...
A non-invasive predictive model for identifying non-diabetic kidney disease in type 2 diabetes mellitus: development and multicenter validation [0.03%]
一项用于2型糖尿病非糖尿病肾病的无创预测模型的研发和多中心验证研究
Yuyan Yang,Yijiang Song,Pinning Feng et al.
Yuyan Yang et al.
Background: This study aimed to develop a non-invasive, simple, and rapid predictive model for identifying non-diabetic kidney disease (NDKD) in patients with type 2 diabetes mellitus (T2DM). ...
Mechanisms of prostatic inflammation-mediated male lower urinary tract symptoms [0.03%]
前列腺炎介导的男性下尿路症状的作用机制
Brandon R Scharpf,Chad M Vezina
Brandon R Scharpf
Lower urinary tract dysfunction (LUTD) is prevalent in aging men. It is characterized by urinary symptoms such as weak stream and more frequent urination, and is linked to a variety of prostate and urethral pathologies. While the leading me...
The associations between volatile organic compounds exposure and urine flow rate in US adults: NHANES 2011-2020 [0.03%]
基于NHANES 2011-2020数据的美国成人尿流率与挥发性有机物暴露关联分析
Xiudeng Yang,Zhixue Zhang
Xiudeng Yang
Objective: Metabolites of volatile organic compounds (mVOCs) have attracted considerable attention in contemporary research. The urine flow rate (UFR) serves as an objective metric for a full evaluation of bladder functio...
Clear cell urothelial carcinoma: a rare but villainous and hostile subtype [0.03%]
透明细胞尿路上皮癌:一种罕见但凶险的亚型
David S Buchinsky,Rajpal Aujla,Robert B Bracken et al.
David S Buchinsky et al.
Clear Cell Urothelial Carcinoma (CCUC) is a rarely reported urothelial carcinoma variant first described in 1995. Due to CCUC's clinical rarity, reporting additional cases may aid future clinicians on surgical and oncological management. We...
Artificial intelligence in prostate cancer: navigating the new frontier of precision uro-oncology [0.03%]
人工智能与前列腺癌:精准泌尿肿瘤学的新前沿导航技术
Ming Liu,Lingfeng Li,Soroush Rais-Bahrami et al.
Ming Liu et al.
Artificial Intelligence (AI) is revolutionizing prostate cancer (PCa) care, addressing the major clinical challenges of subjectivity and overtreatment. Our traditional tools - like PSA, DRE, mpMRI, and Gleason scoring - often lack the preci...
Urine-derived stem cells as a model for age-related kidney degeneration and chronic disease risk [0.03%]
尿液衍生干细胞作为年龄相关性肾脏退行性疾病和慢性疾病风险模型
Pengfei Yu,Jiaqi Li,Huifen Ding et al.
Pengfei Yu et al.
Renal aging contributes to declining kidney function and heightened susceptibility to chronic kidney disease (CKD). A key factor in this process is the diminished number and functionality of renal stem/progenitor cells, though the underlyin...
NCYM facilitates cell proliferation and invasion in Wilms tumor by regulating SIX1/β-catenin axis [0.03%]
NCYM通过调节SIX1/β-catenin轴促进Wilms瘤细胞增殖和侵袭
Zhi Wang,Feng Ning,Lei Tu et al.
Zhi Wang et al.
Recently, accumulating studies demonstrate that some long non-coding RNAs (lncRNAs) contain open read frames and have protein/peptide-coding potential. NCYM is a 109-amino acid product encoded by lncRNA MYCNOS variant 2 that is an antisense...
Tuberculous spondylodiscitis with ureteral involvement: a rare case report [0.03%]
罕见的结核性脊椎骨髓炎伴输尿管受侵病例报告
Nazanin Sadraei,Ali Hekmatnia,Mehdi Salehipour et al.
Nazanin Sadraei et al.
Background: Tuberculosis spondylitis, also known as Pott's disease, is a form of osteomyelitis that primarily affects the vertebral bodies and can lead to severe complications such as paravertebral abscesses, kyphosis, an...