Mechanisms of prostatic inflammation-mediated male lower urinary tract symptoms [0.03%]
前列腺炎介导的男性下尿路症状的作用机制
Brandon R Scharpf,Chad M Vezina
Brandon R Scharpf
Lower urinary tract dysfunction (LUTD) is prevalent in aging men. It is characterized by urinary symptoms such as weak stream and more frequent urination, and is linked to a variety of prostate and urethral pathologies. While the leading me...
The associations between volatile organic compounds exposure and urine flow rate in US adults: NHANES 2011-2020 [0.03%]
基于NHANES 2011-2020数据的美国成人尿流率与挥发性有机物暴露关联分析
Xiudeng Yang,Zhixue Zhang
Xiudeng Yang
Objective: Metabolites of volatile organic compounds (mVOCs) have attracted considerable attention in contemporary research. The urine flow rate (UFR) serves as an objective metric for a full evaluation of bladder functio...
Clear cell urothelial carcinoma: a rare but villainous and hostile subtype [0.03%]
透明细胞尿路上皮癌：一种罕见但凶险的亚型
David S Buchinsky,Rajpal Aujla,Robert B Bracken et al.
David S Buchinsky et al.
Clear Cell Urothelial Carcinoma (CCUC) is a rarely reported urothelial carcinoma variant first described in 1995. Due to CCUC's clinical rarity, reporting additional cases may aid future clinicians on surgical and oncological management. We...
Artificial intelligence in prostate cancer: navigating the new frontier of precision uro-oncology [0.03%]
人工智能与前列腺癌：精准泌尿肿瘤学的新前沿导航技术
Ming Liu,Lingfeng Li,Soroush Rais-Bahrami et al.
Ming Liu et al.
Artificial Intelligence (AI) is revolutionizing prostate cancer (PCa) care, addressing the major clinical challenges of subjectivity and overtreatment. Our traditional tools - like PSA, DRE, mpMRI, and Gleason scoring - often lack the preci...
Urine-derived stem cells as a model for age-related kidney degeneration and chronic disease risk [0.03%]
尿液衍生干细胞作为年龄相关性肾脏退行性疾病和慢性疾病风险模型
Pengfei Yu,Jiaqi Li,Huifen Ding et al.
Pengfei Yu et al.
Renal aging contributes to declining kidney function and heightened susceptibility to chronic kidney disease (CKD). A key factor in this process is the diminished number and functionality of renal stem/progenitor cells, though the underlyin...
NCYM facilitates cell proliferation and invasion in Wilms tumor by regulating SIX1/β-catenin axis [0.03%]
NCYM通过调节SIX1/β-catenin轴促进Wilms瘤细胞增殖和侵袭
Zhi Wang,Feng Ning,Lei Tu et al.
Zhi Wang et al.
Recently, accumulating studies demonstrate that some long non-coding RNAs (lncRNAs) contain open read frames and have protein/peptide-coding potential. NCYM is a 109-amino acid product encoded by lncRNA MYCNOS variant 2 that is an antisense...
Tuberculous spondylodiscitis with ureteral involvement: a rare case report [0.03%]
罕见的结核性脊椎骨髓炎伴输尿管受侵病例报告
Nazanin Sadraei,Ali Hekmatnia,Mehdi Salehipour et al.
Nazanin Sadraei et al.
Background: Tuberculosis spondylitis, also known as Pott's disease, is a form of osteomyelitis that primarily affects the vertebral bodies and can lead to severe complications such as paravertebral abscesses, kyphosis, an...
Efficacy of temsirolimus versus pazopanib in the treatment of advanced renal cell carcinoma: a meta-analysis [0.03%]
替西罗莫司与培唑帕尼治疗晚期肾细胞癌疗效的meta分析研究
Yanni Liu,Cuixue Jiang,Guoyang Zhang et al.
Yanni Liu et al.
Purpose: Temsirolimus and pazopanib serve as first-line therapies for renal cell carcinoma (RCC). This meta-analysis was performed to assess and compare their efficacy, optimal treatment targets, and associated toxicities...
Renal cell carcinoma with unusual morphological features: the clinical utility of next-generation sequencing in distinguishing renal cell tumors [0.03%]
具有不寻常形态特征的肾细胞癌：下一代测序在区分肾细胞肿瘤中的临床应用价值
Jennifer Lee,Xiuping Yu,Yunshin A Yeh
Jennifer Lee
Objectives: Clear cell and papillary renal cell carcinomas (RCC) are the two most common RCC subtypes, accounting for approximately 70% and 15% of kidney cancers, respectively. Clear cell RCC is commonly associated with V...
Impact of commonly used medications on the detection of clinically significant prostate cancer in the targeted biopsy era [0.03%]
药物使用对靶向活检时代临床显著性前列腺癌诊断的影响
Krista N Brackman,Marcelo P Bigarella,Arighno Das et al.
Krista N Brackman et al.
Objectives: To compare prostate cancer rates in magnetic resonance imaging (MRI)-detected lesions for patients who are chronically taking beta-blockers, nonsteroidal anti-inflammatory drugs (NSAIDs), or immunosuppressors....