Radical prostatectomy is associated with favorable outcomes in patients over 80 years old [0.03%]
八十岁以上患者进行根治性前列腺切除术可获得良好的治疗结果
Isaac E Kim Jr,Michael S Leapman,Micah J Kim et al.
Isaac E Kim Jr et al.
Introduction/background: Although surgery is less commonly selected as treatment for localized prostate cancer (PCa) as patients age, outcomes among older patients treated with radical prostatectomy remain unclear. The ob...
Urinary exosomes as promising biomarkers for early kidney disease detection [0.03%]
尿液外泌体作为早期肾脏疾病检测的生物标志物
An-Ping Liu,Tian-Jing Sun,Tong-Ying Liu et al.
An-Ping Liu et al.
Kidney injury and disease pose a significant global health burden. Despite existing diagnostic methods, early detection remains challenging due to the lack of specific molecular markers to identify and stage various kidney lesions. Urinary ...
2'-Hydroxyflavanone inhibits bladder cancer cell proliferation and angiogenesis via regulating miR-99a-5p/mTOR signaling [0.03%]
2'-羟基黄酮通过调节miR-99a-5p/mTOR信号抑制膀胱癌细胞增殖和血管生成
Tianyu Qi,Fei He,Shiqi Wu et al.
Tianyu Qi et al.
Objectives: 2'-Hydroxyflavanone (2HF) has been recognized for its antitumor potential in recent years. In the past decade, the role of miRNAs in tumors has been gradually explored. Since natural compounds may regulate miR...
Cystoscope-free ureteral stent removal: a safe and effective method during the COVID-19 pandemic [0.03%]
一种安全有效的COVID-19疫情期间无膀胱镜输尿管支架取出方法
Jiangcun Silang,Yalong Gu,Ciren Gazang et al.
Jiangcun Silang et al.
Ureteral stent must be removed within a certain period, usually performed under the cystoscope. However, cystoscopic operations procedures carry risks such as urethral injury, hemorrhage, and infection. This study aimed to implement a cysto...
Impact of race-based calculations of eGFR on the management of muscle invasive bladder cancer [0.03%]
基于种族的eGFR计算对肌层浸润性膀胱癌治疗的影响
Amir Khan,Shu Wang,Kathryn Hughes Barry et al.
Amir Khan et al.
Purpose: The estimated glomerular filtration rate (eGFR) has historically been calculated with a race-coefficient multiplier (RCM); however, the RCM has been broadly criticized as inaccurate and a potential contributor to...
Impact of cell plasticity on prostate tumor heterogeneity and therapeutic response [0.03%]
细胞多能性对前列腺肿瘤异质性和治疗反应的影响
Maddison Archer,Kevin M Lin,Kaushik P Kolanukuduru et al.
Maddison Archer et al.
Epithelial-mesenchymal transition (EMT) is a dynamic process of lineage plasticity in which epithelial cancer cells acquire mesenchymal traits, enabling them to metastasize to distant organs. This review explores the current understanding o...
SOX2 control activation of dormant prostate cancer cells in bone metastases by promoting CCNE2 gene expression [0.03%]
SOX2通过促进CCNE2基因表达激活骨转移性前列腺癌细胞
Min Deng,Pei-Zheng Huang,Ze-Yu Huang et al.
Min Deng et al.
Background: Cancer stem cells (CSCs) have a powerful tumor initiation ability, which can promote the early dissemination of single disseminated tumor cells (DTCs), leading to tumor progression. SOX2, a pluripotent inducib...
Non-Hodgkin's primary lymphoma involving the genitourinary tract: histopathological experience from two tertiary hospitals, Western region, Saudi Arabia [0.03%]
沙特阿拉伯西部地区两家三级医院涉及泌尿生殖道的非霍奇金原发性淋巴瘤的病理经验
Haneen Al-Maghrabi,Jaudah Al-Maghrabi
Haneen Al-Maghrabi
Background: Urinary tract and male genital organ lymphoid neoplasms are uncommon, accounting for less than 5% of all primary extranodal lymphomas. There have only been a few small case series and isolated case reports des...
Prioritizing precision: detection of prostate cancer using mri guided fusion needle biopsy across the pennsylvania urologic regional collaborative [0.03%]
精准检测：使用MRI引导的融合针活检在宾夕法尼亚泌尿区域协作中检测前列腺癌
Dennis Head,Ako A Ako,Serge Ginzburg et al.
Dennis Head et al.
Purpose: Targeted prostate biopsies are increasingly being performed by urologists in the United States including those in the Pennsylvania Urologic Regional Collaborative, a physician-led data-sharing and quality improve...
Decreased expression of LncRNA CRYM-AS1 promotes apoptosis through the Hippo-YAP1 signaling pathway leading to diabetic erectile dysfunction [0.03%]
LncRNA CRYM-AS1表达下调通过Hippo-YAP1信号通路促进糖尿病勃起功能障碍的凋亡发生
Ze-Bo Zhang,Ying Chen,Zhan-Sen Huang et al.
Ze-Bo Zhang et al.
Long non-coding RNAs (lncRNAs) primarily engage with mRNA, DNA, proteins, and microRNAs (miRNAs), thereby regulating gene expression; however, its specific role in diabetic erectile dysfunction (DED) has not been studied. This study aims to...