RB1 and p53 are diagnostic markers for treatment-related neuroendocrine prostate cancer: a clinical and pathological analysis of 23 cases [0.03%]
RB1和p53是治疗相关神经内分泌前列腺癌的诊断标志物：23例临床病理分析
Yutao Zhang,Minjing Shi,Yuhao Zhang et al.
Yutao Zhang et al.
The synergistic interplay between RB1 deletions and TP53 mutations drives androgen deprivation therapy (ADT) resistance and neuroendocrine transdifferentiation in advanced prostate cancer, culminating in treatment-related neuroendocrine pro...
Decoding the pro-invasive role of SAA2 in renal cell carcinoma: an exploratory study and experimental validation [0.03%]
解码SAA2在肾细胞癌中的促侵袭作用：探索性研究和实验验证
Yin Chen,Haoqing Shi,Yifan Xu et al.
Yin Chen et al.
Purpose: Currently, there is an urgent need for prognostic prediction models for renal clear cell carcinoma (ccRCC). This study aims to establish a prognostic prediction model based on differential genes associated with T...
Integration of magnetic resonance imaging and deep learning for prostate cancer detection: a systematic review [0.03%]
基于磁共振影像和深度学习的前列腺癌检测：系统性综述
Deepak Kumar,Priyank Yadav,Kavindra Nath et al.
Deepak Kumar et al.
Objectives: This study aims to evaluate the overall impact of incorporating deep learning (DL) with magnetic resonance imaging (MRI) for improving diagnostic performance in the detection and stratification of prostate can...
SPP1A and VEGFC splice isoforms as predictive diagnostic biomarkers for high and low-grade bladder cancer [0.03%]
基于膀胱癌高、低等级预测诊断标志物SPP1A和VEGFC剪接异构体的研究
Akram Mirzaei,Diana Taheri,Behrouz Fattahi et al.
Akram Mirzaei et al.
Objectives: This study aimed to investigate the expression of Vascular endothelial growth factor (VEGF) and Secreted phosphoprotein-1 (SPP1) isoforms in bladder cancer tissue and their correlation with tumor grade and mus...
DeepSeek vs ChatGPT: a comparison study of their performance in answering prostate cancer radiotherapy questions in multiple languages [0.03%]
DeepSeek vs ChatGPT：多语种回答前列腺癌放射治疗问题的性能比较研究
Peng-Wei Luo,Ji-Wen Liu,Xi Xie et al.
Peng-Wei Luo et al.
Introduction: The medical information generated by large language models (LLM) is crucial for improving patient education and clinical decision-making. This study aims to evaluate the performance of two LLMs (DeepSeek and...
Dual role of autophagy in bone metastasis: mechanistic insights and therapeutic targeting [0.03%]
自噬在骨转移中的双刃剑作用：机制见解与治疗靶向策略
Xinyi Gu,Dejian Xiang,Haozhong Zhu et al.
Xinyi Gu et al.
Autophagy, a cellular degradation mechanism, plays a dual role in the progression and therapy of bone metastases in cancers, including prostate cancer. This review delves into the intricate roles of autophagy in both tumor suppression and p...
Jovian Yu,Christina Sharkey,Aria F Olumi et al.
Jovian Yu et al.
Objectives: Extracellular ATP/ADP and its metabolite adenosine play crucial roles in cellular signaling by interacting with P2 and P1/adenosine receptors. These signaling molecules are regulated by ectonucleotidases, whic...
Pseudoaneurysm of the lower pole segmental artery of the kidney following open nephrolithotomy using an avascular approach: a case report [0.03%]
采用无血管入路开放肾切开术后肾下极分支动脉假性动脉瘤一例报告
Reza Kazemi,Faezeh Sadat Jandaghi,Ahmadreza Jannesari et al.
Reza Kazemi et al.
Aneurysms are abnormalities in blood vessels that can be categorized as true aneurysms or pseudoaneurysms. Pseudoaneurysms occur when one or more layers of the blood vessel wall rupture, often as a result of trauma or medical procedures, su...
Genetic factors associated with erectile dysfunction- mendelian randomisation analysis [0.03%]
与勃起功能障碍相关的遗传因素：孟德尔随机化分析
Zejie Qu,Yurong Li,Quangang Yuan et al.
Zejie Qu et al.
Background: Studies have established a strong link between erectile dysfunction (ED) and genetic factors. However, the genetic protective genes associated with ED have yet to be identified. In this study, we used Mendelia...
External ureteral involvement as a result of ovarian cancer initially suspected as endometriosis leading to the diagnosis of squamous cell carcinoma [0.03%]
卵巢癌向外蔓延至输尿管最初被怀疑是子宫内膜异位症后来诊断为鳞状细胞癌
Faezeh Sadat Jandaghi,Reza Kazemi,Moein Bighamian et al.
Faezeh Sadat Jandaghi et al.
Ovarian squamous cell carcinoma [SCC] is a rare and aggressive malignancy that can mimic benign gynecological disorders, often leading to diagnostic delays and suboptimal management. Ureteral obstruction and subsequent hydroureteronephrosis...