Measurement of the absolute value of the optical birefringence of myelin in primate brain tissue [0.03%]
测量灵长类脑组织髓鞘光学双折射的绝对值
Ting Xie,Anna Novoseltseva,Alexander J Gray et al.
Ting Xie et al.
Significance: Researchers require quantitative biomarkers to accurately identify neurodegenerative diseases and quantitatively monitor disease progression. The structural anisotropy of myelin leads to strong optical biref...
Data-driven optimization of preschoolers' hemodynamic response in a VR setup: advancing analytic methods for children's fNIRS naturalistic data with the AICopt method [0.03%]
基于数据的优化：在VR设置中对学龄前儿童的血液动力学反应进行AICopt方法分析
Letizia Contini,Rebecca Re,Paola Pinti et al.
Letizia Contini et al.
Significance: Naturalistic fNIRS data acquired on children enable studying real-world behaviors but challenge standard analysis methods such as block averaging and general linear model (GLM). In naturalistic paradigms, ev...
Multimodal optical imaging combining voltage-sensitive dye ElectroFluor630 with genetically encoded calcium, glutamate, or voltage indicators [0.03%]
结合基因编码钙、谷氨酸或电压指示器的多模态光学成像技术及其电生理特性研究-ElectroFluor630电压敏感染料案例
Katarina D Milicevic,Amal M Abdulkadir,Kaio S Tom et al.
Katarina D Milicevic et al.
Significance: Combining genetically encoded neuronal activity indicators (GENIs), restricted to only one neuron type, with a voltage-sensitive dye (VSD) that reports pan-neuronal activity, could be beneficial for understa...
Data-driven wavelet coherence approach to assess neurovascular coupling in neonatal hypoxic-ischemic encephalopathy [0.03%]
基于数据驱动的小波相干方法评估新生儿缺氧缺血性脑病的神经血管耦合
Srinivas Kota,Soheila Norasteh,Hanli Liu et al.
Srinivas Kota et al.
Significance: Neonatal hypoxic-ischemic encephalopathy (HIE) remains a leading global cause of mortality and morbidity. Neurovascular coupling (NVC), assessed via wavelet transform coherence (WTC) between electroencephalo...
Effect of sleep stage on patterns of fNIRS hemodynamic response to auditory paradigms in 1-month-old Gambian and UK infants [0.03%]
睡眠分期对1月龄冈比亚和英国婴儿听觉刺激功能近红外光谱血流动力学反应模式的影响
Maria Rozhko,Merel van der Straaten,Borja Blanco et al.
Maria Rozhko et al.
Significance: The developmental functional near-infrared spectroscopy (fNIRS) literature relies heavily on measurements acquired during natural sleep, yet it remains unclear whether and how different sleep stages modulate...
Anusha Mishra
Anusha Mishra
Anusha Mishra interviewed David Attwell, Jodrell Professor of Physiology at University College London, whose work has been foundational to our understanding of glial physiology, neurovascular coupling, and vascular contributions to dementia...
Combining membrane potential and calcium imaging in brain slices using the voltage-sensitive dye ElectroFluor630 and the calcium indicator Calbryte520 [0.03%]
结合脑片电压敏感染料ElectroFluor630膜电位记录与Calbryte520钙指示剂钙成像的实验方法
Shirin Ghasemiform,Marco Canepari
Shirin Ghasemiform
Significance: Wide-field imaging from brain slices stained with a voltage-sensitive dye (VSD) and simultaneously loaded with a Ca 2 + indicator allows investigating neuronal excitability and synaptic transmission at ...
Distinct neural signatures of phonemic and semantic verbal fluency: a double dissociation in cortical activation and functional connectivity revealed by fNIRS [0.03%]
基于fNIRS的语音流畅度网络及其双分离机制研究
Yize Cai,Yuexian Hou,Tian Zhu et al.
Yize Cai et al.
Significance: The verbal fluency task (VFT) is a widely used paradigm in neuroimaging, yet its phonemic (pVFT) and semantic (sVFT) variants are frequently treated interchangeably despite limited understanding of their dis...
Zebrafish Ace2N-mNeon expression toolkit for in vivo voltage imaging of neuronal synchrony and cardiac maturation [0.03%]
斑马鱼Ace2N-mNeon在体表达工具包用于神经元同步和心脏成熟电压成像
Zhenzhen Wu,Rui Oliveira Silva,Ruya Houssein et al.
Zhenzhen Wu et al.
Significance: Bioelectricity is a fundamental biophysical property of cells that shapes embryogenesis through neuronal signaling and tissue patterning. Yet techniques for cell-resolved, millisecond-scale voltage imaging i...
Comparative validation of speckle contrast optical spectroscopy against diffuse correlation spectroscopy for monitoring human cerebral blood flow [0.03%]
对比验证光谱散斑对比度光学频谱与扩散相关光谱监测人体脑血流的方法
Tom Y Cheng,Mitchell B Robinson,Marco Renna et al.
Tom Y Cheng et al.
Significance: Within diffuse optics, speckle contrast optical spectroscopy (SCOS) has emerged as a promising alternative to the state-of-the-art technique of diffuse correlation spectroscopy (DCS) for continuous, noninvas...