Utilizing Process Mapping as a Framework for Identifying and Prioritizing Barriers to Antibiotic Delivery in Resource-limited Settings [0.03%]
运用流程图识别和优先处理资源匮乏环境下抗生素递送障碍框架
Elizabeth A Gulleen,Johnblack Kabukye,Maiya Grace Block Ngaybe et al.
Elizabeth A Gulleen et al.
In resource-limited settings, healthcare providers face unique structural barriers to antibiotic delivery. Process mapping (PM) is a low-cost, low-technology approach used to understand the antibiotic delivery process and systematically ide...
Serologic Evidence of Hemorrhagic Fever Virus Spillover in Rural Liberia [0.03%]
利比里亚农村地区出血热病毒溢出的血清学证据
Adam M Schafer,Emmanuel Kerkula,Chanhwa Lee et al.
Adam M Schafer et al.
Background: Outbreaks of zoonotic emerging infectious diseases, including viral hemorrhagic fevers, are increasing in frequency. Clinical detection remains challenging due to the lack of pathognomonic signs or symptoms an...
Population-based Study of Carbapenem-resistant Raoultella spp. Reveals Diverse Repertoire of Carbapenemase Genes [0.03%]
基于人口的碳青霉烯类耐药粗糙假单胞菌研究揭示了多样化的碳青霉烯酶基因库
Nadya Rakovitsky,Mor Lurie-Weinberger,Ophir Kastel et al.
Nadya Rakovitsky et al.
Raoultella species, previously considered an environment bacteria, are emerging as human pathogens. Concerningly, there is a rise in reports of carbapenemase-producing strains. Despite this, specific data on Raoultella planticola and Raoult...
Emphasizing the O in OPAT: A Pathway for Clinic-Initiated Outpatient Parenteral Antimicrobial Therapy (CI-OPAT) at an Academic Center [0.03%]
重视OPAT中的O：学术中心启动门诊抗微生物治疗(CI-OPAT)的途径
Molly McDonough,Michael Yarrington,Jason Funaro et al.
Molly McDonough et al.
Our infectious diseases (ID) clinic began a clinic-initiated outpatient parenteral antimicrobial therapy (CI-OPAT) program to avoid unnecessary emergency department visits or inpatient admissions. In this single-center retrospective case se...
Re-evaluating the Potential Impact of Preexposure Prophylaxis (PrEP) in Achieving HIV Elimination in the United States: Insights From Modeling [0.03%]
在美国实现消除艾滋病目标的预暴露预防（PrEP）潜力再评价：来自模型的见解
Jason Baron,Tamar Tchelidze,Neil Parkin et al.
Jason Baron et al.
Background: Preexposure prophylaxis (PrEP) to prevent HIV-1 acquisition is a critical component of the strategy to achieve epidemic control and elimination goals. Previous studies assessing PrEP needs have not considered ...
Implementation of an Early Transition to Oral Antibiotics for Patients With Nonstaphylococcal Bacteremia via Real-Time Stewardship Intervention [0.03%]
实时 stewardship干预下非肠球菌血流感染患者静脉抗生素到口服抗生素转换的实施
Tyler Tate,Brandon J Smith,J Alex Viehman et al.
Tyler Tate et al.
Background: Oral antibiotics are effective in treating uncomplicated bloodstream infections (BSIs), but they are underused. The objective of this study was to evaluate the impact of a standardized antimicrobial stewardshi...
From Crisis to Control: A Study of Typhoid Conjugate Vaccine Efficacy in Harare, Zimbabwe (2017-2024) [0.03%]
从危机到控制：赞比亚哈拉雷地区结合型伤寒疫苗效力研究（2017-2024）
Talent Bvochora,John Manyara,Gaetan Thilliez et al.
Talent Bvochora et al.
Background: Typhoid fever remains a public health concern in Harare City, Zimbabwe. Recurrent outbreaks are driven by inadequate water, sanitation, and hygiene infrastructure. In 2019, the typhoid conjugate vaccine (TCV) ...
Standardizing Antimicrobial Use in a Resource-Limited Pediatric Surgical Unit in Botswana [0.03%]
博茨瓦纳资源有限的儿科外科病房内抗生素使用的标准化
Alemayehu Ginbo Bedada,Mazvita Rankin,Andrew P Steenhoff et al.
Alemayehu Ginbo Bedada et al.
Background: Antimicrobial resistance is rampant in low- and middle-income countries. Recent data from Princess Marina Hospital (PMH), Botswana, revealed that 100% of pediatric surgical unit patients received antimicrobial...
A Measurement Model to Quantify Systemic Bacilli Load in Severe HIV-Associated Tuberculosis [0.03%]
量化严重HIV相关结核病全身性分枝杆菌负荷的测量模型
Bianca Sossen,Charlotte Schutz,Linda Boloko et al.
Bianca Sossen et al.
Pathogen load is considered fundamental to infection pathobiology but is unobserved or inadequately measured. We used latent variable modeling to characterize HIV-associated tuberculosis mycobacterial load in 519 inpatients. Tests on urine ...
Cutaneous Larva Migrans Within the United States Military Health System-Clinical Presentation and Association With Autochthonous Spread or International Travel [0.03%]
美国军事医疗系统中皮肤幼虫移行症的临床表现及其与本土传播或国际旅行的相关性
Elena M Crecelius,Patrick W Hickey,Alison M Helfrich
Elena M Crecelius
Background: The epidemiology of cutaneous larva migrans (CLM) within the US population is not well described. We seek to describe the epidemiology of CLM, its association with international travel, and its clinical presen...