The Impact of Directly Observed Therapy on Successful Tuberculosis Treatment: A Statistical Analysis of National Notifications Data [0.03%]
直接观察治疗对肺结核成功治疗的影响:全国报告数据统计分析
Ryan Race Thompson,Do Kyung Ryuk,Daniele Maria Pelissari et al.
Ryan Race Thompson et al.
Background: Directly Observed Therapy (DOT) is a recommended modality for tuberculosis (TB) treatment, yet is underutilized in many settings. Although DOT has been evaluated in clinical trials, less is known about its eff...
Efficacy of Immunoglobulin Therapy for Secondary Prevention of Congenital Cytomegalovirus Infection: A Systematic Review and Meta-Analysis [0.03%]
免疫球蛋白治疗先天性巨细胞病毒感染二级预防有效性的系统评价和 meta 分析
Klaudia Gutowska,Anna Kucińska-Chahwan,Marta Bednarek et al.
Klaudia Gutowska et al.
Congenital cytomegalovirus (cCMV) is the leading infectious cause of long-term neuro-sensory impairment. Aim of meta-analysis was to evaluate the efficacy of antenatal immunoglobulin therapy-particularly cytomegalovirus-specific hyperimmune...
Associations Between QuantiFERON-TB Gold Plus IFNγ Concentrations and Progression to Symptomatic Tuberculosis in Global High-Burden TB Settings [0.03%]
QuantiFERON-TB Gold Plus 干扰素γ浓度与结核病高负担地区进展为有症状结核病的关联研究
Justine Sunshine,Michael Shaffer,Linda L Han et al.
Justine Sunshine et al.
Background: Predictive biomarkers for symptomatic tuberculosis (TB) progression would transform targeted prevention efforts. Although interferon-gamma release assays (IGRAs), including QuantiFERON® TB-Gold Plus (QFT-Plus...
Efficacy of a Large Language Model Data Extraction System in Evidence Reviews for Emerging Infectious Diseases: A Randomized Crossover Trial [0.03%]
大型语言模型数据提取系统在新兴传染病证据审查中的有效性的随机交叉试验评估
Masahiro Ishikane,Yuki Kataoka,Yasushi Tsujimoto et al.
Masahiro Ishikane et al.
Background: Rapid evidence synthesis during emerging infectious and re-emerging disease outbreaks is critical, yet traditional systematic reviews rarely meet urgent timelines. Large language models (LLMs) may accelerate e...
Antiviral Dispensing for Influenza Outpatients Younger Than 65 Years With Comorbidities: A Retrospective Cohort Study [0.03%]
一项回顾性队列研究:抗病毒药在小于65岁并存有并发症的流感门诊患者中的使用情况
Grazia Grace Mirabito,Svetlana Masalovich,Timothy M Uyeki et al.
Grazia Grace Mirabito et al.
Background: Real-world evidence on antiviral dispensing for influenza outpatients with underlying medical conditions (UMCs) is limited. We characterized dispensing among influenza outpatients aged
Neurological Manifestations of Mycoplasma pneumoniae Infection in Hospitalized Adults During the 2023-2024 French Epidemic, Clinical Characterization and Comparative Outcomes: A Multicenter Study [0.03%]
法国2023-2024年支原体肺炎流行期间住院成人支原体感染的神经系统表现:临床特征及结果比较多中心研究
Matthieu Holub,Ariane Gavaud,Céline Louapre et al.
Matthieu Holub et al.
Background: Mycoplasma pneumoniae (MP) primarily causes respiratory infections but can lead to neurological manifestations. This study aimed to characterize these manifestations in adults during an epidemic. ...
Caroline B Ewing,Dawd Siraj,Alexander Lepak
Caroline B Ewing
Oseltamivir Resistance in Human Influenza A(H5N1) and A(H7N9) Infections: A Mini Review [0.03%]
人感染H5N1和H7N9流感病毒的奥斯他韦耐药性研究:小结文章
Yacine Abed,Guy Boivin
Yacine Abed
Avian influenza viruses (AIVs) have been reported to cause infections in humans following avian-to-human transmission, resulting in a range of clinical outcomes. A(H5N1) and A(H7N9) infections, which constitute the majority of human AIV cas...
Metabolic Syndrome Is Associated With Increased Risk of Clostridioides difficile Infection Diagnosis and Severe Outcomes [0.03%]
代谢综合征与难辨梭菌感染诊断风险增加及严重结局有关
Stella O Oyewole,Rajat Madan
Stella O Oyewole
Background: Clostridioides difficile infection (CDI) is a major cause of antibiotic-associated diarrhea in the United States. Gut dysbiosis and chronic inflammation are key contributors to CDI susceptibility and severity....
Delays in Tuberculosis Treatment Among People With Pulmonary Tuberculosis in East Africa: Findings From a Prospective Cohort Study [0.03%]
东非肺结核患者治疗延迟:一项前瞻性队列研究的结果
Kirsten Prabhudas-Strycker,Lameck Diero,Winnie Muyindike et al.
Kirsten Prabhudas-Strycker et al.
Background: Although timely tuberculosis (TB) diagnosis and treatment are essential to TB elimination, care delays remain a challenge. Understanding factors associated with delayed TB diagnosis and treatment may inform in...