Determining the Activity of Imipenem/Relebactam Plus Aztreonam Against Constitutive Pseudomonas-Derived Cephalosporinase- and Metallo-β-Lactamase-Producing Pseudomonas aeruginosa in a Hollow Fiber Infection Model [0.03%]
J Nicholas ODonnell,Kelly E Moolick,Avery I Nahorniak et al.
J Nicholas ODonnell et al.
Background: Few treatment options exist for serious infections caused by metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa. This study evaluated imipenem/relebactam (I/R) plus aztreonam (ATM) against Pseudomonas...
Epidemiology and Clinical Features of Cryptococcosis Among Individuals Without HIV Infection: An Observational International Multicenter Study (MSG-11) [0.03%]
Yee-Chun Chen,Sharon C A Chen,Gerald McGwin et al.
Yee-Chun Chen et al.
Background: Infections due to Cryptococcus species occur globally, mostly reported as central nervous system (CNS) infection among persons with HIV infection. Among persons without HIV infection, cryptococcosis is a growi...
Genomic Surveillance of Respiratory Syncytial Virus in Sydney Reveals Rebound in Postpandemic Viral Diversity [0.03%]
Julia M S Herkes,Charles S P Foster,Alice Michie et al.
Julia M S Herkes et al.
Respiratory syncytial virus (RSV) transmission between 2020 and 2025 was impacted by COVID-19-related public health measures, resulting in unprecedented genomic bottlenecks, and postpandemic surges in clinical cases. We performed whole-geno...
Multicenter Evaluation of Ceftazidime/Avibactam in Pediatric Patients Across the United States: Real-World Insights into the Management of Drug-Resistant Gram-Negative Infections [0.03%]
Taylor Morrisette,Grant T Stimes,Gustavo R Alvira-Arill et al.
Taylor Morrisette et al.
Background: Antimicrobial resistance among gram-negative pathogens is a global threat, with children particularly vulnerable due to limited treatment options and age-specific clinical outcomes data. Ceftazidime/avibactam ...
Syphilis Infections Among Women of Reproductive Age in the Southern United States: An Analysis From the Study of Treatment and Reproductive Outcomes (STAR) [0.03%]
Madison Sophia Meyer,Erin Rebecca Carr,Candice A Sternberg et al.
Madison Sophia Meyer et al.
Syphilis is resurging among reproductive-age women in the United States. Among 773 women with and without HIV enrolled in the Study of Treatment and Reproductive Outcomes (STAR), 2.9% had prior/current syphilis, including 1 pregnant partici...
Azole Resistance in Aspergillus fumigatus From Diverse Environments in Ohio, United States, Is Primarily Driven by TR34/L98H and TR46/Y121F/T289A Environmental Signatures [0.03%]
Raees A Paul,Sudharsan Sadhasivam,Timothy Frey et al.
Raees A Paul et al.
Aspergillus fumigatus is a leading global human fungal pathogen. Triazole antifungal drugs are used in clinical settings, while triazole demethylase inhibitor (DMI) fungicides are widely applied in the environment to combat plant fungal dis...
Oscar Herrera-Restrepo,Elizabeth Packnett,Megan K Richards et al.
Oscar Herrera-Restrepo et al.
Background: Invasive meningococcal disease (IMD) is associated with high case-fatality rates and severe long-term sequelae. In the United States (US), IMD incidence rate (IR) is highest among infants aged
Comparison of Hospitalization Costs Associated With Human Metapneumovirus and Respiratory Syncytial Virus Infection in US Adults [0.03%]
Bradley K Ackerson,Emily Rayens,Lina S Sy et al.
Bradley K Ackerson et al.
Hospitalization costs on human metapneumovirus (hMPV) are needed to inform healthcare priorities, including vaccine and treatment development. Among 5775 adult hospitalizations with hMPV or respiratory syncytial virus (RSV), hMPV was associ...
Bridging the Gap: A Needs Assessment of Resources and Support for International Medical Graduates Navigating Visa-related Career Decisions in Infectious Diseases [0.03%]
Brian Chow,Alfredo J Mena Lora,Vera P Luther et al.
Brian Chow et al.
International medical graduates (IMGs) in infectious disease encounter distinct career and immigration-related barriers during training. We conducted a needs-assessment survey to better understand challenges IMGs face. Results underscore th...
Effects of High-Intensity Functional Exercise on Cardiorespiratory Fitness and Physical Function in Older Adults With HIV: A Telerehabilitation Randomized Trial [0.03%]
Alice S Ryan,Vincent C Marconi,Brandon C Briggs et al.
Alice S Ryan et al.
Background: People with HIV (PWH) represent a high-risk patient group that will benefit from easily accessible exercise programs, particularly those centered on high intensity. Yet, limited telerehabilitation programs are...