Genome-wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients [0.03%]
全基因组DNA甲基化研究揭示了GCA患者受累动脉组织中的特异性表观遗传特征
Gonzalo Borrego-Yaniz,Ana Márquez,Elkyn Estupiñán-Moreno et al.
Gonzalo Borrego-Yaniz et al.
Objectives: Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific D...
Thomas Subervie,Thibault Willaume,Amin Maazouzi et al.
Thomas Subervie et al.
Ken Fukuda,Kenji Yamashiro
Ken Fukuda
Trimethoprim/sulfamethoxazole in clinical trials for Granulomatosis with Polyangiitis [0.03%]
利福昔明在Polyangiitis临床试验中与Granulomatosis的关联研究
Jan Willem Cohen Tervaert
Jan Willem Cohen Tervaert
Clinical Significance of Gut Microbiota Community Types for Long-term Response to Fecal Microbiota Transplantation in Patients with Psoriatic Arthritis [0.03%]
粪便微生物移植治疗银屑病关节炎长期疗效的肠道菌群分类意义
Panpan Qin,Maja S Kragsnaes,Dorte K Holm et al.
Panpan Qin et al.
Objective: Fecal microbiota transplantation (FMT) holds promises as a beneficial supplement to methotrexate in patients with psoriatic arthritis (PsA). We therefore investigated how gut bacterial signatures in patients an...
Chitinase 3-Like 1 Promotes Endothelial-to-Mesenchymal Transition in Systemic Sclerosis via mTORC1 Signaling Pathway [0.03%]
软骨素酶3样蛋白1通过mTOR信号途径促进系统性硬化症内皮间质转化
Xiuyuan Wang,Xue Han,Jia Yu et al.
Xiuyuan Wang et al.
Objective: Systemic sclerosis (SSc) is a complicated autoimmune connective tissue disorder. Endothelial-to-mesenchymal transition (EndoMT) contributes to vasculopathy and fibrosis in SSc, yet its underlying mechanism rema...
Chenhui Zhao,Xiaochun Jiang
Chenhui Zhao
Secukinumab after Tocilizumab failure in Giant Cell Arteritis [0.03%]
托西珠单抗治疗失败后的 giant cell arteritis 寰菌素治疗
Olivier Espitia,Marie Morard,Antoine Benichou et al.
Olivier Espitia et al.
Paradoxical Hepatic Encephalopathy in Lupus Nephritis: A Diagnostic Challenge [0.03%]
系统性红斑狼疮肾炎患者的矛盾性肝性脑病——一种诊断陷阱
Xu-Jie Zhou,Rui Wang,Li-Juan He et al.
Xu-Jie Zhou et al.
American College of Rheumatology Guidance Statement for Diagnosis and Management of VEXAS Developed by the International VEXAS Working Group Expert Panel [0.03%]
美国风湿病学会VEXAS诊断和管理指导声明（国际VEXAS工作组专家组制定）
Arsene M Mekinian,Sophie Georgin-Lavaille,Marcela A Ferrada et al.
Arsene M Mekinian et al.
Objective: Vacuoles E1 enzyme X-linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of infl...