Telomere Length of Peripheral Blood Leukocytes Predicts Disease Severity and Worse Survival in Systemic Sclerosis [0.03%]
外周血淋巴细胞端粒长度预测系统性硬化病的严重程度及不良预后
Monica M Yang,Shuo Liu,Michael Wax nd et al.
Monica M Yang et al.
Objective: Peripheral blood leukocyte telomere length (PBL-TL) shortening is associated with systemic sclerosis related interstitial lung disease (SSc-ILD). However, its association with other organ involvement, disease s...
Transition from psoriasis to psoriatic arthritis is characterized by distinct alterations in peripheral blood Tc17, Th17 and CD4+ TEM cells [0.03%]
外周血Tc17、Th17和CD4+TEM细胞的特征性改变参与了银屑病向银屑病关节炎转变的过程
Hanna Graßhoff,Sara Comdühr,Henry Nording et al.
Hanna Graßhoff et al.
Objective: Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the trans...
Performance of an Idiopathic Pulmonary Fibrosis Derived Multibiomarker Panel for Rheumatoid Arthritis-Associated Interstitial Lung Disease [0.03%]
自身免疫性肺纤维化多生物标志物检测在类风湿关节炎相关间质性肺病患者中的性能评估
Brent A Luedders,Daniel Kass,Joshua F Baker et al.
Brent A Luedders et al.
Objective: To assess whether a panel of peripheral blood biomarkers associated with idiopathic pulmonary fibrosis (IPF) is also associated with interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) ut...
A randomized, placebo-controlled trial of hydroxychloroquine in incomplete lupus [0.03%]
羟氯喹治疗不全狼疮的随机、安慰剂对照试验
Nancy J Olsen,Duanping Liao,Judith A James et al.
Nancy J Olsen et al.
Objectives: Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus (ILE). This condition includes individuals with a high risk of prog...
Mesenchymal Stromal Cell Therapy Alleviates Lupus Nephritis Through Inhibiting Caspase-4/5/11-mediated Noncanonical Pyroptosis in Macrophages [0.03%]
间充质基质细胞通过抑制巨噬细胞中的Caspase-4/5/11介导的非经典性焦亡治疗狼疮性肾炎
Sha Liu,Zhikang Wang,Yue Zhang et al.
Sha Liu et al.
Background: Caspase-4/5/11 mediated noncanonical pyroptosis emerges as a contributing factor in immune responses under pathological conditions. However, its precise role in the development of lupus nephritis (LN) remains ...
ZBTB20 Regulating Postnatal Articular Cartilage Development and Homeostasis: Implications for Early-Onset Osteoarthritis [0.03%]
ZBTB20调控软骨终末分化及软骨稳态在早发性 osteoarthritis 发病中的作用及其机制研究
Xianhua Ma,Fei Jiang,Zhenbang Qin et al.
Xianhua Ma et al.
Objective: Mutations in ZBTB20, a transcription factor, are linked to epiphyseal dysplasia and articular degeneration in humans. This study investigates the role of ZBTB20 in regulating articular cartilage growth and inte...
Comparative Real-World Effectiveness of Immunomodulatory Therapies for Prevention of Uveitis Relapse in Behçet's Disease [0.03%]
比较免疫调节疗法预防贝赫切特病复发性葡萄膜炎的现实有效性
Zhenyu Zhong,Jiayi Wang,Lan Xia et al.
Zhenyu Zhong et al.
Purpose: To evaluate comparative effectiveness of cyclosporine, interferon alfa-2a, and adalimumab for the prevention of uveitis relapse in Behçet's disease in real-world settings. ...
Interleukin-23 receptor deficiency in podocytes averts the development of lupus nephritis [0.03%]
podocyte 中的白细胞介素-23受体缺陷可防止狼疮性肾炎的发生
Rong Fu,Afroditi Boulougoura,Shuilian Yu et al.
Rong Fu et al.
Objective: Upregulation of Interleukin 23 (IL-23) in the serum and kidneys of patients with lupus nephritis (LN) has been demonstrated, but its effect on podocytes remains unknown. We hypothesized that IL-23 contributes t...
Response to: "Gut Microbiota Typing and Donor Factors Shape Fecal Microbiota Transplantation Response in Psoriatic Arthritis" [0.03%]
对“肠道微生物分型和供体因素塑造粪便微生物移植在银屑病关节炎中的疗效”的答复
Maja S Kragsnaes,Panpan Qin,Jens Kjeldsen et al.
Maja S Kragsnaes et al.