Diagnostic Value and Treatment Responsiveness of Ultrasound Features in correlation with clinical findings in Early Peripheral Spondyloarthritis [0.03%]
超声波特征与临床表现相关性的早期外周型脊柱关节炎的诊断价值和治疗反应性研究
Wannes Van Hooste,Josephine Braekman,Thomas Renson et al.
Wannes Van Hooste et al.
Objective: To investigate the diagnostic performance of ultrasound features in the evaluation of enthesitis and arthritis in very early peripheral spondyloarthritis (pSpA). ...
Increased plasma microbial tDR-1 in at-risk individuals is associated with decreased conversion to clinical rheumatoid arthritis and reduces an in vitro macrophage type 1 interferon response [0.03%]
血浆微生物tDR-1增加与高危个体临床类风湿关节炎发病风险降低及减少体外巨噬细胞Ⅰ型干扰素反应相关
Anastasiia Phothisane,Tulsi K Joishy,Carolina Ramirez-Becerra et al.
Anastasiia Phothisane et al.
Background: Microbial small RNAs (sRNAs) can regulate human genes. Higher plasma concentrations of microbial tRNA-derived RNA-1 (tDR-1) were previously associated with lower rheumatoid arthritis (RA) disease activity. Thi...
Targeting Obesity in Psoriatic Arthritis: Is It Time For a Paradigm Change? [0.03%]
肥胖在银屑病性关节炎中的作用：是时候改变我们的观念了吗？
Lihi Eder,Rebecca Haberman,Jose U Scher
Lihi Eder
The role of IgM anti-acetylated protein antibodies and B cells in the origin of anti-modified protein autoimmunity in rheumatoid arthritis [0.03%]
抗乙酰化蛋白的IgM自身抗体和B细胞在类风湿关节炎中修饰蛋白自身免疫应答的作用
Aegli Athanasiadou,Sanne Kroos,Renee van de Wetering et al.
Aegli Athanasiadou et al.
Objective: Rheumatoid arthritis (RA) is characterized by anti-modified protein antibodies (AMPAs), including anti-citrullinated (ACPA), anti-carbamylated (anti-CarP), and anti-acetylated (AAPA) protein antibodies. In cont...
Comparative transcriptional profiling of key macrophage and fibroblast subpopulations in rheumatoid arthritis-associated lung disease [0.03%]
类风湿关节炎相关肺病关键巨噬细胞和成纤维细胞亚群的比较转录组分析
Tracy Tabib,Ogechukwu Ezenwa,Joshua Sciurba et al.
Tracy Tabib et al.
Objective: Rheumatoid arthritis (RA) often involves extra-articular complications, including interstitial lung disease (ILD) and/or pulmonary nodules. Transcriptomic profiling of lung tissue provides the opportunity to di...
IgG Glycosylation-Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis [0.03%]
狼疮性肾炎中依赖于IgG糖基化的CLEC7A信号驱动足细胞功能障碍
Rohit Upadhyay,Alexia Orellana,George C Tsokos et al.
Rohit Upadhyay et al.
Background: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end-stage kidney disease and increased mortality. Immunoglobulin G (IgG) from LN patients displays abnormal ...
From Interferon Signature to the Clinical Landscape: Type I Interferonopathies [0.03%]
从干扰素特征到临床谱型：I 型干扰素病学说
Ismail Yaz,Seza Ozen,Hacer N Bildik et al.
Ismail Yaz et al.
Background: Type I interferonopathies are heterogeneous diseases driven by dysregulated IFN-I signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN-I quantification. ...
Effects of Metabolic Dysregulation on Macrophage Polarization in Rheumatoid Arthritis [0.03%]
代谢紊乱对类风湿关节炎巨噬细胞极化的影响
Xinyue Zhang,Xiaoyue Deng,Shixiong Wei et al.
Xinyue Zhang et al.
Rheumatoid arthritis (RA) is a systemic autoimmune disease driven by complex immune dysregulation, in which macrophages play a central pathogenic role. Macrophages accumulate extensively in RA synovium, and their abundance and functional ph...
Zandra E Walton,Deepak A Rao
Zandra E Walton
Rahul Kumar,Niket Verma,Rudra Prosad Goswami
Rahul Kumar