Encephalopathy Post CAR-T Cell Therapy in Relapsed/Refractory Multiple Myeloma: Beyond ICANS [0.03%]
CAR-T细胞治疗后复发难治多发性骨髓瘤患者出现脑病：超越ICANS神经系统综合征
Rita Ahmad,Mackenzie Wild,Tyler Friesen et al.
Rita Ahmad et al.
Human herpesvirus 6 (HHV-6) reactivation is a rare but serious complication of chimeric antigen receptor T-cell (CAR-T) therapy that can overlap with immune effector cell-associated neurotoxicity syndrome (ICANS) or cytokine release syndrom...
Malignancy in Disguise: Transudative Malignant Pleural Effusion from Early-Onset Lung Adenocarcinoma [0.03%]
伪装的恶性肿瘤：早发性肺腺癌引起的漏出性恶性胸腔积液
Ruba Habib,Rayan Sabouh,Rouba Isshak et al.
Ruba Habib et al.
Malignant pleural effusions (MPEs) are almost always exudative, with only an estimated 3-4% meeting biochemical criteria for a transudate. Light's criteria remain the standard method for classifying pleural effusions, and transudative effus...
Clinical Presentation of a Patient With Hemochromatosis After Bariatric Surgery With HFE (H63D) Mutation [0.03%]
具有HFE（H63D）突变的减肥手术后遗传性血色素沉着病患者的临床表现
Samuele Petridis,Karla Baez Rodriguez,Naresh Punjabi et al.
Samuele Petridis et al.
Hereditary hemochromatosis (HH) is a genetic disorder characterized by excessive intestinal iron absorption, most associated with HFE C282Y homozygosity. In contrast, H63D homozygosity is considered a low-penetrance genotype that rarely lea...
Paraparesis, Urinary Dysfunction, and Acute, Therapy-Resistant Heart Failure in a Previously Healthy Patient Should Not Remain Unexplained [0.03%]
previously healthy患者不应该出现的双下肢无力、尿便功能异常和急性难治性心力衰竭病例一例
Josef Finsterer,Sounira Mehri
Josef Finsterer
Aparna Abhirami Rathnam,Harleen Sidhu,Thanushiree Sivalingam et al.
Aparna Abhirami Rathnam et al.
A young woman presented with left hip pain for one week. She had been admitted to another hospital one month prior for right ankle pain and was undergoing treatment for septic arthritis with home IV antibiotics. Imaging of the left hip and ...
Matthew Maharaj,Arun Katwaroo,Priya Ramcharan et al.
Matthew Maharaj et al.
Denosumab, a monoclonal antibody (mAb) targeting receptor activator of nuclear factor-κB ligand (RANKL), is commonly used in managing metabolic bone diseases and giant cell tumors (GCTs) of bone. Growing evidence suggests that RANKL inhibi...
Dynamic LVOT Obstruction as a Cause of Hemodynamic Instability in Takotsubo Syndrome [0.03%]
应激性心肌病(Tako-Tsubo心肌病)中左心室流出道动力型梗阻导致血流动力学不稳定的机制研究
Simran Tanna,Gurleen Sangha,Sohrab Singh et al.
Simran Tanna et al.
Takotsubo syndrome (TTS) frequently presents with chest pain, ST-segment elevation, and troponin elevation, closely mimicking acute coronary syndrome, and can be complicated by acute heart failure and cardiogenic shock. In a subset of patie...
A Perfect Storm in Advanced AIDS: Severe Acute Respiratory Distress Syndrome From Pneumocystis Jirovecii and Mycobacterium Avium Complex Coinfection [0.03%]
艾滋病晚期出现完美风暴：由新型隐球菌和鸟分支杆菌复合感染引起的严重急性呼吸窘迫综合征
Martinez Abdel,Rodriguez Abelardo,Conrad Chouinard et al.
Martinez Abdel et al.
Advanced HIV infection is associated with profound immunosuppression, predisposing patients to opportunistic infections such as Pneumocystis jirovecii pneumonia (PJP) and Mycobacterium avium complex (MAC). PJP can cause severe respiratory d...
Integrating Physiology Into Hyponatremia Algorithms: Moving Beyond Volume Status [0.03%]
将生理学纳入低钠血症算法：超越容量状态
Jodie Mogensen,Livia Frost,Bryan Tucker et al.
Jodie Mogensen et al.
Hyponatremia is a prevalent electrolyte disorder with a broad differential diagnosis, which can pose a challenge for determining the underlying etiology. Academic resources teach two diagnostic frameworks designed to guide a physician to th...
Actinomyces Europaeus: A Case Report of a Rare Subcutaneous Infection Following Abdominoplasty and a Review of the Literature [0.03%]
欧洲念珠菌：腹壁整形术后罕见的亚急性皮下感染病例报告及文献回顾
Simone Gianazza,Luca Broggi,Arline Vechiu et al.
Simone Gianazza et al.
Actinomyces europaeus is an emerging Gram-positive bacterium associated with skin and soft tissue infections. It exhibits intrinsic resistance to multiple antibiotics, and its fastidious growth and the polymicrobial nature of infections oft...