Bidirectional Interaction Between Chronic Kidney Disease and Porphyromonas gingivalis Infection Drives Inflammation and Immune Dysfunction [0.03%]
慢性肾脏病与牙龈卟啉单胞菌感染的双向交互作用驱动炎症和免疫功能障碍
Karina Adamowicz,Andrea Sofia Lima Ribeiro,Anna Golda et al.
Karina Adamowicz et al.
Introduction: Chronic kidney disease (CKD) is characterized by a decline in renal function, increased mortality, and significant impairments in the immune system and function of immune cells. These alterations are often derived by uremic to...
In Silico Design and Characterization of a Multiepitope Vaccine Candidate Against Brucella canis Using a Reverse Vaccinology Approach [0.03%]
基于反向疫苗学方法的犬布鲁氏菌多表位疫苗候选抗原的设计与鉴定
Vicente Arriagada,Alberto Osorio,Crisleri Carrera-Naipil et al.
Vicente Arriagada et al.
Brucella canis is a Gram-negative bacterium that causes canine brucellosis, a zoonotic disease with serious implications for public health and the global economy. Currently, there is no effective preventive vaccine for B. canis. Control mea...
Exploring the Role of Cellular Interactions in the Colorectal Cancer Microenvironment [0.03%]
探究细胞相互作用在结直肠癌微环境中的作用
Jiadai Tang,Liuhan Chen,Xin Shen et al.
Jiadai Tang et al.
Colorectal cancer (CRC) stands as one of the tumors with globally high incidence and mortality rates. In recent years, researchers have extensively explored the role of the tumor immune microenvironment (TME) in CRC, highlighting the crucia...
Metal Hypersensitivity in Patients With Failure of Joint Prosthesis Treatment [0.03%]
人工关节置换治疗失败患者的金属过敏反应
Jana Bruna,Jarmila Prochazkova,Stepan Podzimek et al.
Jana Bruna et al.
The objective of this study is to measure lymphocyte responses to metal antigens using MELISA (memory lymphocyte immunostimulation assay) test-modified lymphocyte transformation test (mLTT) and to evaluate metal sensitization in patients wi...
Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes [0.03%]
抗磷脂综合征患者HLA-DRB1等位基因的分布及其与抗磷脂抗体存在和损伤指数的相关性
Ewa Haladyj,Barbara Stypinska,Agata Matusiewicz et al.
Ewa Haladyj et al.
Antiphospholipid syndrome (APS) is frequently coexisting with systemic lupus erythematosus (SLE) and the knowledge on its genetic background is essential. The objective of this work was to assess distribution of human leukocyte antigen (HLA...
Serum Proteomics of Experimental Malaria-Associated ARDS Reveals a Regulation of Acute-Phase Response Proteins [0.03%]
实验性疟疾相关ARDS的血清蛋白组学显示急性期反应蛋白的调控
Lívia Rosa-Fernandes,Verônica Feijoli Santiago,Yasmin da Silva-Santos et al.
Lívia Rosa-Fernandes et al.
Malaria is a parasitic infectious disease considered a public health problem. Acute respiratory distress syndrome (ARDS) is a complication in malaria-infected individuals with a high mortality rate (80% to 100%) and can occur before, during...
Identification of a Prognostic Signature Based on Tumor-Infiltrating B Lymphocyte mRNA in Head and Neck Squamous Cell Carcinoma [0.03%]
基于头颈部鳞状细胞癌肿瘤浸润B淋巴细胞mRNA的预后特征识别
Mingjun Zhang,Qi Sun,Yisong Yao et al.
Mingjun Zhang et al.
Introduction: Tumor-infiltrating B cells (TILBs) are an important part of the immune response during tumor regulation. However, the significance of B cells in immunotherapy has not been fully determined. Methods: In this study, highly expre...
Chemically Induced Senescence Prompts Functional Changes in Human Microglia-Like Cells [0.03%]
化学诱导的衰老促使人类类似小胶质细胞的功能发生变化
S Armanville,C Tocco,Z Haj Mohamad et al.
S Armanville et al.
In response to various stressors, cells can enter a state called cellular senescence which is characterized by irreversible cell cycle arrest and a senescence-associated secretory phenotype (SASP). The progressive accumulation of senescent ...
Plasma-Derived Neuronal Exosomal CircRNAs as Potential Biomarkers for Central Nervous System Infections [0.03%]
血浆来源的神经元外泌体环状RNA作为中枢神经系统感染潜在生物标志物
Rui Zhang,Bihan Deng,Shuaibing Shi et al.
Rui Zhang et al.
Infections of central nervous system (ICNSs) are inflammatory diseases caused by infectious agents that can infiltrate the brain and spinal cord through various routes, including the bloodstream, peripheral nerves, or cranial nerves. Exosom...
Clinical Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) in Pediatric Functional Constipation: Impact on Immunological Indicators and Gut Microbiota [0.03%]
经皮电神经刺激(TENS)在儿童功能性便秘中的临床疗效：对免疫指标和肠道微生物的影响
Piao Guo,Xue Ning Zhang,Xin Yu Jin et al.
Piao Guo et al.
Objective: This study was conducted to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) in treating pediatric functional constipation (FC) and to explore its mechanisms by analyzing changes in serum neurotran...