Genome-Guided and De Novo Transcriptome Analysis of a Newly Isolated Neopyropia yezoensis Strain With Heat Tolerance [0.03%]
通过基因组指导和从头转录组分析一个新的具有耐热性的海带（Neopyropia yezoensis）菌株
Jong-Il Choi,Jiae Kim
Jong-Il Choi
Background: The escalating threats of global warming and the increasing demand for sustainable resources have driven research towards identifying resilient organisms capable of thriving under changing environmental condit...
Metabolic Status and Expression Level of SREBP mRNA and Mir-33 Among Children Conceived by Assisted Reproductive Technology [0.03%]
辅助生殖技术子代儿童的代谢状况及SREBP mRNA和Mir-33表达水平
Yifan Cui,Yuqian Wang,Xiaoxia Wang et al.
Yifan Cui et al.
Background: Due to the growth in the global consumption of assisted reproductive technology (ART), it is possible that long-term health impacts on offspring have come into focus. ART has offered a welcome solution to infe...
Chaperonins in Hepatocellular Carcinoma: Unveiling Their Role in Tumor Proliferation and Immune Modulation Through Multiomics Analysis [0.03%]
肝细胞癌中的分子伴侣蛋白：通过多组学分析揭示其在肿瘤增殖和免疫调节中的作用
Shou-Hua Wang,Feng-Ya Lv,Yuan-Jie Liu et al.
Shou-Hua Wang et al.
Background: Chaperonins are crucial regulators of tumor biology by controlling the stability and function of oncogenic and tumor-suppressor proteins, influencing various tumorigenic signaling pathways. Although chaperonin...
A Novel Mitochondria-Associated Programmed Cell Death-Related Prognostic Model and Validation of Oncogene INHBB in Colorectal Cancer [0.03%]
结直肠癌中与线粒体相关程序性细胞死亡的新预测模型及肿瘤基因INHBB的验证
Yanqing Sun,Chun Gao,Dong Jia et al.
Yanqing Sun et al.
Objective: The objective of this study is to explore mitochondria-associated programmed cell death (mtPCD)-related key biomarkers for patients with colorectal cancer (CRC). ...
Discovery Potential Hub Genes and Pathways in Keloid Fibroblast Development Based on Bioinformatics Analysis [0.03%]
基于生物信息学分析的瘢痕疙瘩成纤维细胞发育中的关键基因和通路研究
Boao Zhao,Wei Zhang,Wende Yao et al.
Boao Zhao et al.
Background: Keloid is a common pathological scar tissue, which invades the surrounding normal skin and leads to symptoms such as pain, pruritus, erythema, and edema, thereby impacting the quality of life. In this study, w...
Single-Cell RNA Sequencing Reveals the Therapeutic Effects of Electroacupuncture at BL23 on Hyperuricemia-Induced Nephritis [0.03%]
单细胞RNA测序揭示电针BL23治疗高尿酸血症肾损伤的机制
Yiyang Hu,Xueyan Song,Haichang Li et al.
Yiyang Hu et al.
Hyperuricemia (HUA) is a metabolic disorder characterized by elevated serum uric acid (UA) level, which would trigger inflammatory processes contributing to kidney damage. Acupuncture stimulation of BL23, a therapeutic strategy in tradition...
Genetic Insights Into the Relationship Between Menstrual Factors and Site-/Age-Specific Bone Mineral Density [0.03%]
遗传学视角下的月经因素与特定部位/年龄的骨矿物质密度之间的关系探讨
Sheng Li,Yan-Yu Zhu,Xiao Hu et al.
Sheng Li et al.
Backgrounds: Observational studies have suggested possible links between reproductive factors and bone mineral density (BMD) and osteoporosis (OP), but the causal impact of menstrual factors on BMD remains obscure. ...
P3H4 Enhances the Proliferation, Invasion, and Glycolysis of Hepatocellular Carcinoma Cells [0.03%]
P3H4促进肝癌细胞增殖、侵袭和糖酵解
Lili Yan,Yandan Fan,Ji Lv et al.
Lili Yan et al.
Objective: The study is aimed at investigating the functions of P3H4 in liver cancer. Materials and methods: The TCGA and CPTAC liver c...
Sphingolipid Metabolism Dysregulation Drives Immune Microenvironment Remodeling and Predicts Prognosis in Bladder Cancer [0.03%]
鞘脂代谢失调驱动膀胱癌免疫微环境重塑并可用于预测预后
Zechun Peng,Jie Yang,Ruipeng Jia et al.
Zechun Peng et al.
The role of sphingolipid metabolism (SM) dysregulation in promoting bladder cancer (BLCA) progression and influencing patient prognosis has been well documented. To enhance therapeutic strategies, we aimed to identify key sphingolipid metab...
PTGS2 Is Involved in Osteonecrosis of the Femoral Head and Bone Marrow Edema [0.03%]
PTGS2参与股骨头坏死及骨髓水肿发病过程
Chongsen Lin,Ran Li,HongDuo Lu et al.
Chongsen Lin et al.
Background: Osteonecrosis of the femoral head (ONFH) is a challenging global health issue with an unclear pathogenesis, complicating the development of effective treatment strategies. Bone marrow edema (BME) is a critical...