Discovery Potential Hub Genes and Pathways in Keloid Fibroblast Development Based on Bioinformatics Analysis [0.03%]
基于生物信息学分析的瘢痕疙瘩成纤维细胞发育中的关键基因和通路研究
Boao Zhao,Wei Zhang,Wende Yao et al.
Boao Zhao et al.
Background: Keloid is a common pathological scar tissue, which invades the surrounding normal skin and leads to symptoms such as pain, pruritus, erythema, and edema, thereby impacting the quality of life. In this study, w...
Single-Cell RNA Sequencing Reveals the Therapeutic Effects of Electroacupuncture at BL23 on Hyperuricemia-Induced Nephritis [0.03%]
单细胞RNA测序揭示电针BL23治疗高尿酸血症肾损伤的机制
Yiyang Hu,Xueyan Song,Haichang Li et al.
Yiyang Hu et al.
Hyperuricemia (HUA) is a metabolic disorder characterized by elevated serum uric acid (UA) level, which would trigger inflammatory processes contributing to kidney damage. Acupuncture stimulation of BL23, a therapeutic strategy in tradition...
Genetic Insights Into the Relationship Between Menstrual Factors and Site-/Age-Specific Bone Mineral Density [0.03%]
遗传学视角下的月经因素与特定部位/年龄的骨矿物质密度之间的关系探讨
Sheng Li,Yan-Yu Zhu,Xiao Hu et al.
Sheng Li et al.
Backgrounds: Observational studies have suggested possible links between reproductive factors and bone mineral density (BMD) and osteoporosis (OP), but the causal impact of menstrual factors on BMD remains obscure. ...
P3H4 Enhances the Proliferation, Invasion, and Glycolysis of Hepatocellular Carcinoma Cells [0.03%]
P3H4促进肝癌细胞增殖、侵袭和糖酵解
Lili Yan,Yandan Fan,Ji Lv et al.
Lili Yan et al.
Objective: The study is aimed at investigating the functions of P3H4 in liver cancer. Materials and methods: The TCGA and CPTAC liver c...
Sphingolipid Metabolism Dysregulation Drives Immune Microenvironment Remodeling and Predicts Prognosis in Bladder Cancer [0.03%]
鞘脂代谢失调驱动膀胱癌免疫微环境重塑并可用于预测预后
Zechun Peng,Jie Yang,Ruipeng Jia et al.
Zechun Peng et al.
The role of sphingolipid metabolism (SM) dysregulation in promoting bladder cancer (BLCA) progression and influencing patient prognosis has been well documented. To enhance therapeutic strategies, we aimed to identify key sphingolipid metab...
PTGS2 Is Involved in Osteonecrosis of the Femoral Head and Bone Marrow Edema [0.03%]
PTGS2参与股骨头坏死及骨髓水肿发病过程
Chongsen Lin,Ran Li,HongDuo Lu et al.
Chongsen Lin et al.
Background: Osteonecrosis of the femoral head (ONFH) is a challenging global health issue with an unclear pathogenesis, complicating the development of effective treatment strategies. Bone marrow edema (BME) is a critical...
A Computational Investigation of Small Peptide of Methyl Jasmonate and Human Complement Factor in Ageing [0.03%]
甲基茉莉酸和人补体因子的小肽在衰老中的计算研究
Oluwafemi G Oluwole,Ngalla Jillani,Afolake Arowolo et al.
Oluwafemi G Oluwole et al.
Background: Ageing contributes to the onset of various diseases. It is accompanied by malfunctioning and deterioration of the body systems. Identifying the biomarkers for the prediction, diagnosis, management, or prognosi...
Cathepsin Levels and Atrial Fibrillation Risk: Insights From Bidirectional and Multivariable Mendelian Randomization Analyses [0.03%]
猫hepsin水平与房颤风险的关系：双向和多变量孟德尔随机化分析的见解
Fang Ye,Ruya Zhou,Haiying Lin et al.
Fang Ye et al.
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia, contributing to substantial morbidity, mortality, and healthcare burden. While genome-wide association studies (GWAS) have identified numerous ge...
Mapping the Research Landscape of Exercise and Breast Cancer: A Bibliometric Analysis From 2020 to 2024 [0.03%]
2020-2024年运动与乳腺癌研究领域文献计量分析
Jian Li,LiYing Qiang,MingYue Jiao et al.
Jian Li et al.
Even though there is strong evidence that exercise improves breast cancer patients' quality of life, treatment tolerance, and survival, disparate research initiatives and uneven clinical acceptance underscore the need for a thorough synthes...
Identification and Validation of the Key Genes of Diabetic Vasculopathy: Evidence Based on Bioinformatics Analysis and Animal Study [0.03%]
基于生物信息学分析和动物实验的糖尿病血管病变关键基因鉴定及验证
Feng Li,Chi Geng,Xing Xu et al.
Feng Li et al.
Backgrounds: The mechanisms contributing to diabetic vasculopathy have not been fully understand. Methods: First, we identified differe...