Discovery of Essential Genes as Possible Targets for Prostate Cancer Drug Development [0.03%]
发现潜在的前列腺癌药物作用靶点基因
Md Amanat Ullah Arman,Md Selim Reza,Muhammad Habibulla Alamin et al.
Md Amanat Ullah Arman et al.
Prostate cancer (PCa) is a major malignancy affecting men and is a significant contributor to global male mortality. Over the past decade, several new treatments for advanced PCa have been approved; however, opportunities remain for the dev...
Risk Prediction of Colon Cancer Metastasis and Bioinformatics Analysis of Aspirin Treatment [0.03%]
结直肠癌转移的风险预测及阿司匹林治疗的生物信息学分析
Jing Li,Xinyue Yu,Jingjing Shao et al.
Jing Li et al.
Background: Metastasis is a major adverse prognostic factors of colon cancer. Aspirin chemoprophylaxis may improve outcomes for metastatic colon cancer patients. This study aimed to determine the impact of metastasis-rela...
CLDN22 Serves as a Novel Prognostic Biomarker and Immunotherapy Response Predictor in Gliomas: A Comprehensive Multiomics Analysis [0.03%]
CLDN22作为胶质瘤新型预后生物标志物和免疫治疗反应预测因子的综合多组学分析
Hui Zheng,Jingsong Cheng,Jialin Liu et al.
Hui Zheng et al.
Background: The claudin gene family plays crucial roles in cancer biology, yet their comprehensive molecular characteristics and clinical implications in gliomas remain unclear. ...
MicroRNA Binding Site Polymorphisms in Hepatocellular Carcinoma: Implications for Pathogenesis, Prognosis, and Therapeutic Response [0.03%]
肝细胞癌中的微小核糖核酸结合位点多态性：对发病机制、预后和治疗反应的意义
Sara Rezapour,Farin Khodam Mohammadi,Mahmoud Darweesh et al.
Sara Rezapour et al.
Hepatocellular carcinoma (HCC) is a major global health challenge, characterized by complex molecular mechanisms. This review focuses on the crucial roles of microRNAs (miRNAs) in HCC development, progression, and therapeutic response. The ...
Data-Driven Investigation of Traditional Chinese Medicine Approaches for Optimizing Multiple Clinical Parameters in Esophageal Cancer Treatment [0.03%]
基于数据的中医优化治疗改善食管癌患者多项临床指标的研究探索
Ying Fang,Jifang Peng,Dandan Yang et al.
Ying Fang et al.
Background: The purpose of the study is to evaluate the comparative effects of conventional perioperative care and conventional care plus Traditional Chinese Medicine (TCM) appropriate technology on blood glucose fluctuat...
Genome Wide Identification and Characterization of LIM Domain Associated Gene Superfamily in Common Bean (Phaseolus vulgaris L.) [0.03%]
常见豆(Legenes vulgars)中LIM结构域相关基因超家族的全基因组鉴定与特征分析
Raiyyan Abdur Rahim,Maria Chowdhory,Mahmuda Akhter Hasi et al.
Raiyyan Abdur Rahim et al.
LIM genes are essential for cytoskeletal organization and cellular stress responses in plants. This study conducted a comprehensive genome-wide investigation of LIM domain-associated genes in Phaseolus vulgaris. This study expands LIM gene ...
A Multi-Faceted Approach to Explore the Role of Inflammatory CAFs, Providing Prognostic Value and Therapeutic Implications in Lung Adenocarcinoma [0.03%]
多管齐下探究炎症性CAFs在肺腺癌中的作用及预后和治疗意义
Xiaoyue Zhou,Cong Fu,Ying Fu et al.
Xiaoyue Zhou et al.
Background: Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer, where its complex tumor microenvironment (TME) significantly influences disease progression and treatment response. Inflammatory cancer-ass...
CLEC4G Reverses Lenvatinib Resistance in Hepatocellular Carcinoma by Suppressing PD-1 Expression via the Wnt/ β-Catenin Pathway [0.03%]
Claudin 4 阻碍肝细胞癌免疫逃逸并逆转仑伐替尼耐药性：通过Wnt/β-catenin信号通路抑制PD-1表达
Kemin Xiao,Jin Yan,Guangxi He et al.
Kemin Xiao et al.
Objective: The objective was to analyze the effect of C-type lectin domain family 4 member G (CLEC4G) on hepatocellular carcinoma (HCC) and investigate its impact on lenvatinib (Lenva) resistance as well as the underlying...
Machine Learning and Mendelian Randomization Identify Allergic Rhinitis as Nasopharyngeal Carcinoma Risk Factor With Validated Potential Candidate Biomarkers [0.03%]
机器学习和孟德尔随机化识别出过敏性鼻炎是具有潜在候选生物标志物的鼻咽癌风险因素
Minqi Chen,Bo Yang,Changming Gong et al.
Minqi Chen et al.
Background: Despite extensive research, nasopharyngeal carcinoma (NPC) remains a complex malignancy with poorly understood cellular dynamics and risk factors. The relationship between allergic rhinitis and NPC development...
Transcriptomic Analysis of Gingival Tissues: Insights Into Gene Expression Profiles [0.03%]
牙龈组织转录组分析：基因表达谱的见解
Saravanan Sampoornam Pape Reddy,Yash Dhiman,Delfin Lovelina Francis et al.
Saravanan Sampoornam Pape Reddy et al.
Objectives: The aim of this study was to understand the transcriptome and molecular pathways that drive unique functional characteristics of human gingiva. ...