Correlation Analysis of Pyroptosis-Related Genes CASP1, NLRP3, AIM2, and NLRP1 With Lung Adenocarcinoma [0.03%]
焦亡相关基因CASP1、NLRP3、AIM2和NLRP1与肺腺癌的相关性分析
Lingling Zhu,Yongqian Zhang,Xiaojing Chen et al.
Lingling Zhu et al.
Purpose: This study is aimed at exploring the role of pyroptosis-related genes in the development, immune infiltration, and clinical features of lung adenocarcinoma. Method: Pyroptosis-related genes were searched using online databases, inc...
PANoptosis-Related Optimal Model (PROM): A Novel Prognostic Tool Unveiling Immune Dynamics in Lung Adenocarcinoma [0.03%]
PANoptosis相关最优模型(PROM):一种揭示肺腺癌免疫动力学的新预后工具
Jianming Peng,Leijie Tong,Rui Liang et al.
Jianming Peng et al.
Background: PANoptosis, a recently characterized inflammatory programmed cell death modality orchestrated by the PANoptosome complex, integrates molecular mechanisms of pyroptosis, apoptosis, and necroptosis. Although this pathway potential...
Establishment of a Lactylation-Related Gene Signature for Hepatocellular Carcinoma Applying Bulk and Single-Cell RNA Sequencing Analysis [0.03%]
利用批量和单细胞RNA序列分析建立乳酰化相关基因特征用于肝细胞癌的研究
Lianghe Yu,Yan Shi,Zhenyu Zhi et al.
Lianghe Yu et al.
Background: Lactylation is closely involved in cancer progression, but its role in hepatocellular carcinoma (HCC) is unclear. The present work set out to develop a lactylation-related gene (LRG) signature for HCC. Methods: The lactylation s...
A Prognostic Riskscore Model Related to Helicobacter pylori Infection in Stomach Adenocarcinoma [0.03%]
胃腺癌根除幽门螺杆菌后的预后风险模型
Jing Peng,Qi Yan,Wennan Pei et al.
Jing Peng et al.
Background: Helicobacter pylori (HP) is associated with the development of various stomach diseases, one of the major risk factors for stomach adenocarcinoma (STAD). Methods: The HP infection score between tumor and normal groups was compar...
Multiomics Analysis of Exportin Family Reveals XPO1 as a Novel Target for Clear Cell Renal Cell Carcinoma [0.03%]
出口蛋白家族的多组学分析揭示XPO1是透明细胞肾细胞癌的一个新靶点
Yanhong Hao,Hongchun Lv,Xu Yan et al.
Yanhong Hao et al.
Background: Recently, exportin gene family members have been demonstrated to play essential roles in tumor progression. However, research on the clinical significance of exportin gene family members is limited in clear cell renal cell carci...
The High-Quality Genome Sequencing and Analysis of Red Raspberry (Rubus idaeus L.) [0.03%]
高质量的红树莓(Rubus idaeus L.)基因组测序和分析
Haopeng Zhang,Weihua Li,Guodong Li et al.
Haopeng Zhang et al.
Red raspberry (Rubus idaeus L.), which is an important nutritional source for human health, belongs to fruit crops of the Rosaceae family. Here, we used Pacific Biosciences single-molecule real-time (SMRT) sequencing and high-throughput chr...
Identification of the hsa_circ_0001314-Related ceRNA Network in Breast Cancer With Bioinformatics Analysis [0.03%]
基于生物信息学分析的circRNA-cancer数据库中hsa_circ_0001314相关ceRNA网络在乳腺癌中的识别
Yuge Ma,Bing Zhang,Liping Wang et al.
Yuge Ma et al.
Circular RNA (circRNA) serves as a competitive endogenous RNA (ceRNA) that plays a pivotal role in the initiation and progression of breast cancer (BC). However, compared to other noncoding RNAs (ncRNAs), research on circRNA in BC is still ...
Genome-Wide Association Study for Test-Day Milk Yield, Proteins, and Composition Traits of Crossbred Dairy Cattle in Ethiopia [0.03%]
用于交叉杂交乳用母牛在埃塞俄比亚的测试日鲜奶产量、蛋白质和构成性状的全基因组关联分析研究
B Rekik,T Mestawet,A Girma et al.
B Rekik et al.
Identifying genetic regions and candidate genes that influence milk production traits is critical for understanding genetic inheritance and improving both the quality and quantity of milk in dairy cattle. Crossbred dairy cattle significantl...
EIF2S1 Silencing Impedes Neuroblastoma Development Through GPX4 Inactivation and Ferroptosis Induction [0.03%]
EIF2S1沉默通过GPX4失活和诱导铁死亡抑制神经母细胞瘤的发生发展
Zhen Li,Yunhui Wang,Shubin Liang et al.
Zhen Li et al.
Background: Neuroblastoma (NB) is one of the most devastating malignancies in children, accounting for a high mortality rate due to limited treatment options. This study is aimed at elucidating the role of the ferroptosis-related EIF2S1 gen...
M6A Modification and Transcription Analysis of LncRNA in Cerebral Ischemia/Reperfusion Injury [0.03%]
M6A修饰及长链非编码RNA在脑缺血再灌注损伤中的表达与功能分析
Jierong Mo,Zhiquan Li,Zhengfei Yang et al.
Jierong Mo et al.
LncRNA is a major factor in the occurrence and development of many diseases. However, its mechanism in cerebral ischemia/reperfusion injury (CIRI) is yet unknown. In this study, the transcriptional level and methylation modification level o...