Inflammatory Cell Interactions in the Rotator Cuff Microenvironment: Insights From Single-Cell Sequencing [0.03%]
肩袖微环境中炎症细胞互作的单细胞测序解析
Wencai Liu,Xinyu Wang,Yuhao Yu et al.
Wencai Liu et al.
Rotator cuff injuries are a common cause of shoulder pain and dysfunction, with chronic inflammation complicating recovery. Recent advances in single-cell RNA sequencing (scRNA-seq) have provided new insights into the immune cell interactio...
In Vitro Culture of Aegle marmelos Against Media Composition Stress: Molecular Identification, Media, and Enzyme Optimization for Higher Growth Yields [0.03%]
木果楝离体培养及其培养基和酶优化研究
Magdy I Bahnasy,Ashraf B Abdel Razik,Mohamed F Ahmed et al.
Magdy I Bahnasy et al.
Aegle marmelos, known for its spiky appearance, is a versatile tree found worldwide. In the Indian medical tradition, this therapeutic tree is utilized to treat various ailments. It is commonly propagated through seeds, although they have a...
SMPD3 as a Potential Biomarker and Therapeutic Target in Hepatocellular Carcinoma [0.03%]
SMPD3作为肝细胞癌潜在的生物标志物和治疗靶点
Dan Zhu,Lei Cao
Dan Zhu
Background and Aims: Hepatocellular carcinoma (HCC) is a prevalent and aggressive liver cancer with high mortality rates. Sphingomyelin phosphodiesterase 3 (SMPD3) has recently been suggested to play an antitumor role in several cancers. Th...
Frequency of Genetic Testing Among Patients With Epithelial Ovarian, Fallopian Tube, and Peritoneal Cancers: A Strategy to Improve Compliance [0.03%]
上皮性卵巢癌、输卵管癌和腹膜癌患者的基因检测频率：提高依从性的策略
Jude Nawlo,Kevin Espino,Deanna Gerber et al.
Jude Nawlo et al.
Purpose: In 2014, the Society of Gynecologic Oncology (SGO) recommended universal germline testing for all patients with epithelial ovarian cancer (EOC), fallopian tube cancer (FTC), or peritoneal cancer (PC). Despite this position statemen...
Construction and Validation of a T Cell Exhaustion-Related Prognostic Signature in Cholangiocarcinoma [0.03%]
肝癌相关T细胞耗竭预后标志物的构建与验证
Changshi Qian,Yuqiao Sun,Yihuai Yue
Changshi Qian
Objective: T cell exhaustion (TEX) is a critical determinant of immune resistance. This study was performed to investigate the key genes linked to TEX in cholangiocarcinoma (CCA) and construct a TEX-associated gene signature to forecast the...
Analysis of Gene Regulatory Networks of Taro (Colocasia esculenta (L.) Schott.) Soluble Starch Synthase Based on DeGN and KASP Marker Development [0.03%]
基于DeGN和KASP标记开发的食用蕉可溶性淀粉合成酶基因调控网络分析
Lu Jiang,Jianmei Yin,Li Wang et al.
Lu Jiang et al.
Taro (Colocasia esculenta (L.) Schott.) is an important edible and economically valuable crop that is also a source of high-quality starch. Its quality is determined by the content and proportion of amylopectin. Based on transcriptome seque...
Naveed Ul Mushtaq,Seerat Saleem,Aadil Rasool et al.
Naveed Ul Mushtaq et al.
In environments with high levels of stress conditions, plants accumulate various metabolic products under stress conditions. Among these products, amino acids have a cardinal role in supporting and maintaining plant developmental processes....
Establishing a Prognostic Model Correlates to Inflammatory Response Pathways for Prostate Cancer via Multiomic Analysis of Lactylation-Related Genes [0.03%]
通过乳酰化相关基因的多组学分析建立与前列腺癌预后模型相关的炎症反应通路
Qinglong Du,CuiYu Meng,Wenchao Zhang et al.
Qinglong Du et al.
Prostate cancer (PCa) continues to pose substantial clinical challenges, with molecular heterogeneity significantly impacting therapeutic decision-making and disease trajectories. Emerging evidence implicates protein lactylation-a novel epi...
Machine Learning and Weighted Gene Coexpression Network-Based Identification of Biomarkers Predicting Immune Profiling and Drug Resistance in Lung Adenocarcinoma [0.03%]
基于机器学习和加权基因共表达网络的生物标志物识别，预测肺腺癌的免疫特征和药物抗性
Tian Zhang,Han Zhou
Tian Zhang
Background: The prognosis for lung adenocarcinoma (LUAD) is poor, and the recurrence rate is high. Thus, to evaluate patients' prognoses and direct therapy choices, new prognostic markers are desperately needed. Methods: First, gene modules...
Unraveling the PANoptosis Landscape in Osteosarcoma: A Single-Cell Sequencing and Machine Learning Approach to Prognostic Modeling and Tumor Microenvironment Analysis [0.03%]
解开骨肉瘤中的PANoptosis景观：单细胞测序和机器学习在预后建模和肿瘤微环境分析中的应用
Xue-Yang Gui,Jun-Fei Wang,Yi Zhang et al.
Xue-Yang Gui et al.
Background: Osteosarcoma (OS) is a highly aggressive bone malignancy prevalent in children and adolescents, characterized by poor prognosis and limited therapeutic options. The tumor microenvironment (TME) and cell death mechanisms such as ...