Senescence intensifies bleomycin-induced injury in idiopathic pulmonary fibrosis lung epithelial cells [0.03%]
衰老加重了博莱霉素诱导的特发性肺纤维化上皮细胞损伤
Jane Read,Andrew T Reid,Claire Thomson et al.
Jane Read et al.
Introduction: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease involving injury and a dysregulated repair response of an ageing epithelium. Here we investigate the contribution of senescence and telomere short...
Absolute and relative intensity of physical activity after lung cancer surgery [0.03%]
肺癌手术后体力活动的绝对强度和相对强度
Eva Arents,Sarah Haesevoets,Francesca Van Hulle et al.
Eva Arents et al.
After NSCLC surgery, patients spend the most time at a very low relative intensity of PA. Absolute and relative measures align at group level but individual agreement is limited. Capacity-anchored metrics are needed for personalised PA asse...
The association between dysphagia and the risk of acute exacerbation of COPD: a systematic review and meta-analysis [0.03%]
吞咽困难与慢性阻塞性肺疾病急性加重风险相关性系统评价和 meta 分析
Xinqi Ma,Yue Zhu,Qing Zhao et al.
Xinqi Ma et al.
Background: Acute exacerbations of COPD (AECOPD) significantly impair patients' quality of life and contribute to higher healthcare burdens and mortality. Recent evidence suggests a potential link between dysphagia and AE...
Relationship between cognitive failures, sleepiness and road traffic incidents in patients with untreated obstructive sleep apnoea and controls [0.03%]
未经治疗的阻塞性睡眠呼吸暂停患者与对照组的道路交通事件的认知障碍、嗜睡关系研究
Akshay Dwarakanath,Dipansu Ghosh,Vinod Palissery et al.
Akshay Dwarakanath et al.
Introduction: Current guidelines emphasise assessing "excessive sleepiness" and severity of sleep disordered breathing (SDB) when advising patients with obstructive sleep apnoea about driving. However, accidents can occur...
Enhancing lung health in children with structural damage and malformations: trial protocol for a randomised controlled trial of azithromycin for airway infection prevention [0.03%]
结构异常和畸形儿童预防呼吸道感染减少肺损伤的临床研究方案：阿奇霉素随机对照试验
Marika Nathalie Rønne,Frederik Fouirnaies Buchvald,Elisabeth Søgaard Christiansen et al.
Marika Nathalie Rønne et al.
Background: Children with early-onset structural lung damage or lung and airway malformations - congenital or acquired - are highly susceptible to recurrent respiratory tract infections, leading to frequent hospitalisatio...
Acute and 14-day effects of tiotropium/olodaterol on cardiopulmonary function in COPD [0.03%]
噻托溴铵/奥达特罗对慢性阻塞性肺疾病心肺功能的急性及2周效应
Thomas Kayser,Nadja Struß,René Pflock et al.
Thomas Kayser et al.
Background: Lung hyperinflation in COPD adversely affects cardiac function and may influence autonomic nervous system activity. The onset of cardiac improvement with dual bronchodilator therapy remains uncertain. ...
Transitions to and reversion from a persistent frequent-exacerbator state in COPD [0.03%]
慢性阻塞性肺疾病急性加重频发状态的转变及逆转特征分析
Delphine Vauterin,Frauke Van Vaerenbergh,Lowie E G W Vanfleteren et al.
Delphine Vauterin et al.
Background: Preventing acute exacerbations in COPD (AECOPDs) is key in striving for disease stability. To investigate the differential impact of risk factors across AECOPD phenotypes, we identified baseline health determi...
Measuring the effect of azithromycin in chronic respiratory disease using continuous cough monitoring: an open-label exploratory trial [0.03%]
采用连续监测咳嗽的方法评估阿奇霉素对慢性呼吸道疾病的疗效：开放标签探索性试验
Dominic L Sykes,Kayleigh Brindle,Syed Kazmi et al.
Dominic L Sykes et al.
Background: Azithromycin is beneficial in a multitude of respiratory diseases; however, its effects on both subjective and objective measures of cough have been less extensively studied. Traditional 24-h cough counting as...
Integrating remote patient monitoring into pulmonary rehabilitation: a feasibility randomised controlled trial [0.03%]
远程患者监测融入肺康复的可行性随机对照试验
Evelyn Etruw,Virginia Huynh,Heather Sharpe et al.
Evelyn Etruw et al.
Background: Digital remote patient monitoring (DRPM) may enhance pulmonary rehabilitation (PR) by supporting continuous symptom tracking and early intervention, key features of effective disease management. This study exa...
Immunotherapy-related interstitial lung disease: a call to improve risk stratification and diagnostic consistency [0.03%]
免疫治疗相关性间质性肺疾病：提高风险分层和诊断一致性的呼吁
Laura Fabbri,Katerina Antoniou,Torsten Gerriet Blum et al.
Laura Fabbri et al.
A standardised risk assessment before initiating ICI treatment may improve early detection and management of IR-ILD. Multidisciplinary collaboration is crucial for enhancing patient safety, improving treatment outcomes and advancing researc...