Cleft Palate Induced by Mycophenolate Mofetil Is Associated with miR-4680-3p and let-7c-5p in Human Palate Cells [0.03%]
霉酚酸酯诱导的腭裂与人腭细胞中的miR-4680-3p和let-7c-5p有关
Hiroki Yoshioka,Hanane Horita,Yosuke Tsukiboshi et al.
Hiroki Yoshioka et al.
Background/Objectives: Cleft palate is a birth defect associated with environmental and genetic factors. Disturbance of microRNAs (miRNAs) and exposure to medicinal agents during pregnancy can cause cleft palate. Although an association bet...
miRNA Library Preparation Optimisation for Low-Concentration and Low-Volume Paediatric Plasma Samples [0.03%]
用于低浓度和低体积儿科血浆样本的miRNA文库准备优化
Oenone Rodgers,Chris Watson,Thomas Waterfield
Oenone Rodgers
Background: Analysing circulating miRNAs in paediatric plasma is challenging due to typically low sample volumes. The QIAseq miRNA UDI Library Kit (Qiagen, Hilden, Germany) was selected as it has a proven track record with a specific protoc...
Differential Expression of miRNAs Between Young-Onset and Late-Onset Indian Colorectal Carcinoma Patients [0.03%]
年轻型和老年型印度结直肠癌患者的miRNA差异表达分析
Sumaiya Moiz,Barsha Saha,Varsha Mondal et al.
Sumaiya Moiz et al.
Reports indicate a worldwide increase in the incidence of Early-Onset Colorectal Carcinoma (EOCRC) (
Long Intergenic Non-Coding RNAs and BRCA1 in Breast Cancer Pathogenesis: Neighboring Companions or Nemeses? [0.03%]
长的非编码RNA和BRCA1在乳腺癌发生中的作用：毗邻伴侣还是敌人？
Olalekan Olatunde Fadebi,Thabiso Victor Miya,Richard Khanyile et al.
Olalekan Olatunde Fadebi et al.
Breast cancer is one of the leading causes of mortality among women, primarily due to its complex molecular landscape and heterogeneous nature. The tendency of breast cancer patients to develop metastases poses significant challenges in cli...
Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells [0.03%]
氟喹啉恩诺沙星的抗HIV-1效果及对CEM-SS细胞中促病毒hsa-miR-132加工的调控作用
Verena Schlösser,Helen Louise Lightfoot,Christine Leemann et al.
Verena Schlösser et al.
Background: Despite tremendous advances in antiretroviral therapy (ART) against HIV-1 infections, no cure or vaccination is available. Therefore, discovering novel therapeutic strategies remains an urgent need. In that se...
Kajetan Kiełbowski,Anna Jędrasiak,Estera Bakinowska et al.
Kajetan Kiełbowski et al.
Psoriasis is a chronic immune-mediated disease with complex pathogenesis. The altered proliferation and differentiation of keratinocytes, together with the activity of dendritic cells and T cells, are crucial drivers of psoriasis progressio...
In Silico Prediction of Maize microRNA as a Xanthine Oxidase Inhibitor: A New Approach to Treating Hyperuricemia Patients [0.03%]
基于计算预测的玉米microRNA作为黄嘌呤氧化酶抑制剂及治疗高尿酸血症患者的新型策略研究
Manas Joshi,Mohd Mabood Khan
Manas Joshi
Introduction: Hyperuricemia is characterized by increased uric acid (UA) in the body. The ability to block xanthine oxidase (XO) is a useful way to check how different bioactive molecules affect hyperuricemia. Previous re...
Plasma Humanin and Non-Coding RNAs as Biomarkers of Endothelial Dysfunction in Rheumatoid Arthritis: A Pilot Study [0.03%]
血浆人因素和非编码RNA作为类风湿关节炎血管内皮功能障碍生物标志物的初步研究
Donatella Coradduzza,Sara Cruciani,Biagio Di Lorenzo et al.
Donatella Coradduzza et al.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disorder associated with an increased risk of cardiovascular disease (CVD), largely driven by peripheral endothelial dysfunction (ED). Humanin, a mitochondrial-derived peptide, h...
Integrative Analysis of Whole-Genome and Transcriptomic Data Reveals Novel Variants in Differentially Expressed Long Noncoding RNAs Associated with Asthenozoospermia [0.03%]
整合全基因组和转录组数据分析发现与弱精症相关的差异表达长链非编码RNA的新变异
Maria-Anna Kyrgiafini,Maria Katsigianni,Themistoklis Giannoulis et al.
Maria-Anna Kyrgiafini et al.
Background/Objectives: Asthenozoospermia, characterized by reduced sperm motility, is a common cause of male infertility. Emerging evidence suggests that noncoding RNAs, particularly long noncoding RNAs (lncRNAs), play a critical role in th...
Alessia Finotti,Roberto Gambari
Alessia Finotti
The discovery of the involvement of microRNAs (miRNAs) in cystic fibrosis (CF) has generated increasing interest in the past years, due to their possible employment as a novel class of drugs to be studied in pre-clinical settings of therape...