Assessment of isomiR Discrimination Using Commercial qPCR Methods [0.03%]
商业qPCR方法中异构体miRNA（isomiR）区分能力的评估
Rogan Magee,Aristeidis G Telonis,Tess Cherlin et al.
Rogan Magee et al.
We sought to determine whether commercial quantitative polymerase chain reaction (qPCR) methods are capable of distinguishing isomiRs: variants of mature microRNAs (miRNAs) with sequence endpoint differences. We used two commercially availa...
Repression of RNA Polymerase II Transcription by B2 RNA Depends on a Specific Pattern of Structural Regions in the RNA [0.03%]
B2 RNA通过RNA的特定结构区域模式抑制RNA聚合酶II转录
Steven L Ponicsan,Jennifer F Kugel,James A Goodrich
Steven L Ponicsan
B2 RNA is a mouse non-coding RNA that binds directly to RNA polymerase II (Pol II) and represses transcription by disrupting critical interactions between the polymerase and promoter DNA. How the structural regions within B2 RNA work togeth...
Expression of miRNAs in the Relationship Between Periodontitis and Cardiovascular Diseases: A Systematic Review [0.03%]
牙周病和心血管疾病关系中的miRNA表达：一项系统评价
Objectives: Periodontitis is a chronic inflammatory disease that could influence the pathophysiology of cardiovascular diseases through immunoinflammatory and epigenetic mechanisms. MicroRNAs (miRNAs) could be key mediato...