Human-Specific Suppression of Hepatic Fatty Acid Catabolism by RNA-Binding Protein HuR [0.03%]
RNA结合蛋白HuR特异性抑制人肝脏脂肪酸分解代谢作用
Shohei Takaoka,Marcos E Jaso-Vera,Xiangbo Ruan
Shohei Takaoka
RNA-binding proteins (RBPs) play essential roles in all major steps of RNA processing. Genetic studies in human and mouse models support that many RBPs are crucial for maintaining homeostasis in key tissues/organs, but to what extent the fu...
Navigating the Landscape of Exosomal microRNAs: Charting Their Pivotal Role as Biomarkers in Hematological Malignancies [0.03%]
外泌体微小RNA的研究现状及其在血液系统恶性肿瘤生物标志物中的作用展望
Manlio Fazio,Fabio Stagno,Giuseppa Penna et al.
Manlio Fazio et al.
Under physiological and pathological conditions, all cells release extracellular vesicles named exosomes, which act as transporters of lipidic, protein, and genetic material from parent to recipient cells. Neoplastic cells can secrete highe...
Same Fragments, Different Diseases: Analysis of Identical tRNA Fragments Across Diseases Utilizing Functional and Abundance-Based Databases [0.03%]
相同的片段，不同的疾病——利用功能和丰度数据库跨疾病分析相同的tRNA片段
Adesupo Adetowubo,Sathyanarayanan Vaidhyanathan,Andrey Grigoriev
Adesupo Adetowubo
Background/Objectives: Transfer RNA-derived fragments (tRFs) are small non-coding RNAs increasingly implicated in gene regulation and disease, yet their target specificity and disease relevance remain poorly understood. This is an explorato...
Correction: Garmaa et al. A Systematic Review and Meta-Analysis of microRNA Profiling Studies in Chronic Kidney Diseases. Non-Coding RNA 2024, 10, 30 [0.03%]
关于Garmaa等人的系统回顾和荟萃分析：慢性肾脏疾病中微小核糖核酸谱研究的纠正，非编码rna 2024, 10, 30
Gantsetseg Garmaa,Stefania Bunduc,Tamás Kói et al.
Gantsetseg Garmaa et al.
Text Correction [...].
Published Erratum
Non-coding RNA. 2025 Jul 30;11(4):57. DOI:10.3390/ncrna11040057 2025
Partners in Silencing: Decoding the Mammalian Argonaute Interactome [0.03%]
沉默的伙伴：解码哺乳动物Argonaute互作组蛋白质组学研究
Srinaath Narasimhan,Stefan J Erkeland
Srinaath Narasimhan
MicroRNAs (miRNAs) are key post-transcriptional regulators controlling gene expression across several cellular processes, including development, proliferation, and apoptosis. Their biogenesis involves a multi-step pathway, including the pro...
The Role of Non-Coding RNAs in the Regulation of Oncogenic Pathways in Breast and Gynaecological Cancers [0.03%]
非编码RNA在乳腺和妇科肿瘤致癌通路调控中的作用
Ammar Ansari,Aleksandra Szczesnowska,Natalia Haddad et al.
Ammar Ansari et al.
Female cancers such as breast and gynaecological cancers contribute to a significant global health burden and are a leading cause of fatality among women. With current treatment options often limited by resistance to cytotoxic drugs, side e...
Andrea Corsi,Tonia De Simone,Angela Valentino et al.
Andrea Corsi et al.
Background/Objectives: Non-coding microRNA-34a (miR-34a) regulates the expression of key factors involved in several cellular processes, such as differentiation, apoptosis, proliferation, cell cycle, and senescence. Deregulation of the expr...
DEAD-Box Helicase 3 Modulates the Non-Coding RNA Pool in Ribonucleoprotein Condensates During Stress Granule Formation [0.03%]
DEAD盒解旋酶3在应激颗粒形成过程中调节核糖核蛋白凝聚体中的非编码RNA池大小
Elizaveta Korunova,B Celia Cui,Hao Ji et al.
Elizaveta Korunova et al.
Stress granule formation is a type of liquid-liquid phase separation in the cytoplasm, leading to RNA-protein condensates that are associated with various cellular stress responses and implicated in numerous pathologies, including cancer, n...
The Good, the Bad, or Both? Unveiling the Molecular Functions of LINC01133 in Tumors [0.03%]
好坏兼备？揭开长链非编码RNA LINC01133在肿瘤中的分子功能之谜
Leandro Teodoro Júnior,Mari Cleide Sogayar
Leandro Teodoro Júnior
Background/Objectives: Increasing evidence suggests that lncRNAs are core regulators in the field of tumor progression, with context-specific functions in oncogenic tumorigenesis. LINC01133, a lncRNA that has been identified as both an onco...
circRNA/miRNA Networks Regulate KLF4 in Tumor Development [0.03%]
circRNA/miRNA网络在肿瘤发生发展中调控KLF4基因的作用机制研究
Raffaele Frazzi,Enrico Farnetti,Davide Nicoli
Raffaele Frazzi
Background/Objectives: Krüppel-like factor 4 (KLF4) emerged as an epigenetically regulated gene in a variety of settings, including cell reprogramming and malignant cell proliferation. The aim of the present manuscript is to explore the re...